KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CHI3L1
Full Name:
Chitinase-3-like protein 1
Alias:
39 kDa synovial protein; Cartilage glycoprotein 39; Cartilage glycoprotein-39; CH3L1; GP39; GP-39; HC-gp39; HCgp-39; HCGP-3P; YKL40; YKL-40
Type:
Adhesion protein
Mass (Da):
42625
Number AA:
383
UniProt ID:
P36222
International Prot ID:
IPI00002147
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0043169
GO:0004568
GO:0005201
PhosphoSite+
KinaseNET
Biological Process:
GO:0006032
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y27
S
A
Y
K
L
V
C
Y
Y
T
S
W
S
Q
Y
Site 2
Y28
A
Y
K
L
V
C
Y
Y
T
S
W
S
Q
Y
R
Site 3
Y34
Y
Y
T
S
W
S
Q
Y
R
E
G
D
G
S
C
Site 4
S40
Q
Y
R
E
G
D
G
S
C
F
P
D
A
L
D
Site 5
Y77
E
W
N
D
V
T
L
Y
G
M
L
N
T
L
K
Site 6
T92
N
R
N
P
N
L
K
T
L
L
S
V
G
G
W
Site 7
S103
V
G
G
W
N
F
G
S
Q
R
F
S
K
I
A
Site 8
S107
N
F
G
S
Q
R
F
S
K
I
A
S
N
T
Q
Site 9
S111
Q
R
F
S
K
I
A
S
N
T
Q
S
R
R
T
Site 10
T113
F
S
K
I
A
S
N
T
Q
S
R
R
T
F
I
Site 11
S115
K
I
A
S
N
T
Q
S
R
R
T
F
I
K
S
Site 12
T118
S
N
T
Q
S
R
R
T
F
I
K
S
V
P
P
Site 13
S122
S
R
R
T
F
I
K
S
V
P
P
F
L
R
T
Site 14
Y141
G
L
D
L
A
W
L
Y
P
G
R
R
D
K
Q
Site 15
S188
G
K
V
T
I
D
S
S
Y
D
I
A
K
I
S
Site 16
Y189
K
V
T
I
D
S
S
Y
D
I
A
K
I
S
Q
Site 17
S195
S
Y
D
I
A
K
I
S
Q
H
L
D
F
I
S
Site 18
T216
H
G
A
W
R
G
T
T
G
H
H
S
P
L
F
Site 19
S220
R
G
T
T
G
H
H
S
P
L
F
R
G
Q
E
Site 20
S230
F
R
G
Q
E
D
A
S
P
D
R
F
S
N
T
Site 21
S235
D
A
S
P
D
R
F
S
N
T
D
Y
A
V
G
Site 22
T237
S
P
D
R
F
S
N
T
D
Y
A
V
G
Y
M
Site 23
Y239
D
R
F
S
N
T
D
Y
A
V
G
Y
M
L
R
Site 24
Y243
N
T
D
Y
A
V
G
Y
M
L
R
L
G
A
P
Site 25
S264
G
I
P
T
F
G
R
S
F
T
L
A
S
S
E
Site 26
T266
P
T
F
G
R
S
F
T
L
A
S
S
E
T
G
Site 27
S269
G
R
S
F
T
L
A
S
S
E
T
G
V
G
A
Site 28
S270
R
S
F
T
L
A
S
S
E
T
G
V
G
A
P
Site 29
T288
P
G
I
P
G
R
F
T
K
E
A
G
T
L
A
Site 30
Y318
I
L
G
Q
Q
V
P
Y
A
T
K
G
N
Q
W
Site 31
Y328
K
G
N
Q
W
V
G
Y
D
D
Q
E
S
V
K
Site 32
S333
V
G
Y
D
D
Q
E
S
V
K
S
K
V
Q
Y
Site 33
S336
D
D
Q
E
S
V
K
S
K
V
Q
Y
L
K
D
Site 34
Y340
S
V
K
S
K
V
Q
Y
L
K
D
R
Q
L
A
Site 35
S362
D
L
D
D
F
Q
G
S
F
C
G
Q
D
L
R
Site 36
T373
Q
D
L
R
F
P
L
T
N
A
I
K
D
A
L
Site 37
T383
I
K
D
A
L
A
A
T
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation