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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SOX6
Full Name:
Transcription factor SOX-6
Alias:
Type:
Transcription protein
Mass (Da):
91893
Number AA:
828
UniProt ID:
P35712
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006325
GO:0007517
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
S
K
Q
A
T
S
P
F
A
C
A
A
D
Site 2
T21
A
D
G
E
D
A
M
T
Q
D
L
T
S
R
E
Site 3
T25
D
A
M
T
Q
D
L
T
S
R
E
K
E
E
G
Site 4
S26
A
M
T
Q
D
L
T
S
R
E
K
E
E
G
S
Site 5
S33
S
R
E
K
E
E
G
S
D
Q
H
V
A
S
H
Site 6
S39
G
S
D
Q
H
V
A
S
H
L
P
L
H
P
I
Site 7
S53
I
M
H
N
K
P
H
S
E
E
L
P
T
L
V
Site 8
T58
P
H
S
E
E
L
P
T
L
V
S
T
I
Q
Q
Site 9
S71
Q
Q
D
A
D
W
D
S
V
L
S
S
Q
Q
R
Site 10
S75
D
W
D
S
V
L
S
S
Q
Q
R
M
E
S
E
Site 11
S81
S
S
Q
Q
R
M
E
S
E
N
N
K
L
C
S
Site 12
S88
S
E
N
N
K
L
C
S
L
Y
S
F
R
N
T
Site 13
Y90
N
N
K
L
C
S
L
Y
S
F
R
N
T
S
T
Site 14
S91
N
K
L
C
S
L
Y
S
F
R
N
T
S
T
S
Site 15
T95
S
L
Y
S
F
R
N
T
S
T
S
P
H
K
P
Site 16
S96
L
Y
S
F
R
N
T
S
T
S
P
H
K
P
D
Site 17
S98
S
F
R
N
T
S
T
S
P
H
K
P
D
E
G
Site 18
S106
P
H
K
P
D
E
G
S
R
D
R
E
I
M
T
Site 19
S114
R
D
R
E
I
M
T
S
V
T
F
G
T
P
E
Site 20
T116
R
E
I
M
T
S
V
T
F
G
T
P
E
R
R
Site 21
T119
M
T
S
V
T
F
G
T
P
E
R
R
K
G
S
Site 22
S126
T
P
E
R
R
K
G
S
L
A
D
V
V
D
T
Site 23
T133
S
L
A
D
V
V
D
T
L
K
Q
K
K
L
E
Site 24
T145
K
L
E
E
M
T
R
T
E
Q
E
D
S
S
C
Site 25
S150
T
R
T
E
Q
E
D
S
S
C
M
E
K
L
L
Site 26
S151
R
T
E
Q
E
D
S
S
C
M
E
K
L
L
S
Site 27
S158
S
C
M
E
K
L
L
S
K
D
W
K
E
K
M
Site 28
T170
E
K
M
E
R
L
N
T
S
E
L
L
G
E
I
Site 29
T180
L
L
G
E
I
K
G
T
P
E
S
L
A
E
K
Site 30
S183
E
I
K
G
T
P
E
S
L
A
E
K
E
R
Q
Site 31
S192
A
E
K
E
R
Q
L
S
T
M
I
T
Q
L
I
Site 32
T196
R
Q
L
S
T
M
I
T
Q
L
I
S
L
R
E
Site 33
S218
E
Q
K
K
L
A
A
S
Q
I
E
K
Q
R
Q
Site 34
Y303
T
Y
K
P
G
D
N
Y
P
V
Q
F
I
P
S
Site 35
S343
N
Q
R
L
K
G
L
S
D
R
F
G
R
N
L
Site 36
T352
R
F
G
R
N
L
D
T
F
E
H
G
G
G
H
Site 37
Y361
E
H
G
G
G
H
S
Y
N
H
K
Q
I
E
Q
Site 38
Y370
H
K
Q
I
E
Q
L
Y
A
A
Q
L
A
S
M
Site 39
S380
Q
L
A
S
M
Q
V
S
P
G
A
K
M
P
S
Site 40
S387
S
P
G
A
K
M
P
S
T
P
Q
P
P
N
T
Site 41
T388
P
G
A
K
M
P
S
T
P
Q
P
P
N
T
A
Site 42
T394
S
T
P
Q
P
P
N
T
A
G
T
V
S
P
T
Site 43
T397
Q
P
P
N
T
A
G
T
V
S
P
T
G
I
K
Site 44
S399
P
N
T
A
G
T
V
S
P
T
G
I
K
N
E
Site 45
T410
I
K
N
E
K
R
G
T
S
P
V
T
Q
V
K
Site 46
S411
K
N
E
K
R
G
T
S
P
V
T
Q
V
K
D
Site 47
S428
A
A
Q
P
L
N
L
S
S
R
P
K
T
A
E
Site 48
S429
A
Q
P
L
N
L
S
S
R
P
K
T
A
E
P
Site 49
T433
N
L
S
S
R
P
K
T
A
E
P
V
K
S
P
Site 50
S439
K
T
A
E
P
V
K
S
P
T
S
P
T
Q
N
Site 51
S442
E
P
V
K
S
P
T
S
P
T
Q
N
L
F
P
Site 52
T444
V
K
S
P
T
S
P
T
Q
N
L
F
P
A
S
Site 53
S451
T
Q
N
L
F
P
A
S
K
T
S
P
V
N
L
Site 54
T453
N
L
F
P
A
S
K
T
S
P
V
N
L
P
N
Site 55
S454
L
F
P
A
S
K
T
S
P
V
N
L
P
N
K
Site 56
S462
P
V
N
L
P
N
K
S
S
I
P
S
P
I
G
Site 57
S463
V
N
L
P
N
K
S
S
I
P
S
P
I
G
G
Site 58
S466
P
N
K
S
S
I
P
S
P
I
G
G
S
L
G
Site 59
S476
G
G
S
L
G
R
G
S
S
L
D
I
L
S
S
Site 60
S477
G
S
L
G
R
G
S
S
L
D
I
L
S
S
L
Site 61
S486
D
I
L
S
S
L
N
S
P
A
L
F
G
D
Q
Site 62
T495
A
L
F
G
D
Q
D
T
V
M
K
A
I
Q
E
Site 63
S527
H
G
V
D
G
K
L
S
S
I
N
N
M
G
L
Site 64
S528
G
V
D
G
K
L
S
S
I
N
N
M
G
L
N
Site 65
T544
C
R
N
E
K
E
R
T
R
F
E
N
L
G
P
Site 66
S557
G
P
Q
L
T
G
K
S
N
E
D
G
K
L
G
Site 67
T571
G
P
G
V
I
D
L
T
R
P
E
D
A
E
G
Site 68
S585
G
S
K
A
M
N
G
S
A
A
K
L
Q
Q
Y
Site 69
Y592
S
A
A
K
L
Q
Q
Y
Y
C
W
P
T
G
G
Site 70
Y593
A
A
K
L
Q
Q
Y
Y
C
W
P
T
G
G
A
Site 71
Y608
T
V
A
E
A
R
V
Y
R
D
A
R
G
R
A
Site 72
S616
R
D
A
R
G
R
A
S
S
E
P
H
I
K
R
Site 73
S617
D
A
R
G
R
A
S
S
E
P
H
I
K
R
P
Site 74
S649
A
F
P
D
M
H
N
S
N
I
S
K
I
L
G
Site 75
S657
N
I
S
K
I
L
G
S
R
W
K
S
M
S
N
Site 76
S661
I
L
G
S
R
W
K
S
M
S
N
Q
E
K
Q
Site 77
S663
G
S
R
W
K
S
M
S
N
Q
E
K
Q
P
Y
Site 78
Y670
S
N
Q
E
K
Q
P
Y
Y
E
E
Q
A
R
L
Site 79
Y671
N
Q
E
K
Q
P
Y
Y
E
E
Q
A
R
L
S
Site 80
S678
Y
E
E
Q
A
R
L
S
K
I
H
L
E
K
Y
Site 81
Y685
S
K
I
H
L
E
K
Y
P
N
Y
K
Y
K
P
Site 82
Y688
H
L
E
K
Y
P
N
Y
K
Y
K
P
R
P
K
Site 83
Y690
E
K
Y
P
N
Y
K
Y
K
P
R
P
K
R
T
Site 84
S716
E
Y
K
Q
L
M
R
S
R
R
Q
E
M
R
Q
Site 85
T726
Q
E
M
R
Q
F
F
T
V
G
Q
Q
P
Q
I
Site 86
T751
P
G
A
I
T
M
A
T
T
T
P
S
P
Q
M
Site 87
T753
A
I
T
M
A
T
T
T
P
S
P
Q
M
T
S
Site 88
S755
T
M
A
T
T
T
P
S
P
Q
M
T
S
D
C
Site 89
T759
T
T
P
S
P
Q
M
T
S
D
C
S
S
T
S
Site 90
S760
T
P
S
P
Q
M
T
S
D
C
S
S
T
S
A
Site 91
S763
P
Q
M
T
S
D
C
S
S
T
S
A
S
P
E
Site 92
S764
Q
M
T
S
D
C
S
S
T
S
A
S
P
E
P
Site 93
S766
T
S
D
C
S
S
T
S
A
S
P
E
P
S
L
Site 94
S768
D
C
S
S
T
S
A
S
P
E
P
S
L
P
V
Site 95
S772
T
S
A
S
P
E
P
S
L
P
V
I
Q
S
T
Site 96
S778
P
S
L
P
V
I
Q
S
T
Y
G
M
K
T
D
Site 97
T784
Q
S
T
Y
G
M
K
T
D
G
G
S
L
A
G
Site 98
S788
G
M
K
T
D
G
G
S
L
A
G
N
E
M
I
Site 99
Y804
G
E
D
E
M
E
M
Y
D
D
Y
E
D
D
P
Site 100
Y807
E
M
E
M
Y
D
D
Y
E
D
D
P
K
S
D
Site 101
S813
D
Y
E
D
D
P
K
S
D
Y
S
S
E
N
E
Site 102
Y815
E
D
D
P
K
S
D
Y
S
S
E
N
E
A
P
Site 103
S817
D
P
K
S
D
Y
S
S
E
N
E
A
P
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation