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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RFC2
Full Name:
Replication factor C subunit 2
Alias:
A1; A1 40 kDa; Activator 1 40 kDa; Activator 1 subunit 2; Replication factor C (activator 1) 2; Replication factor C 40 kDa; RF-C 40 kDa; RFC40
Type:
DNA replication
Mass (Da):
39157
Number AA:
354
UniProt ID:
P35250
International Prot ID:
IPI00017412
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005663
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003689
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0006297
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
G
E
V
E
A
Q
D
S
D
P
A
P
A
F
S
Site 2
S25
S
D
P
A
P
A
F
S
K
A
P
G
S
A
G
Site 3
S30
A
F
S
K
A
P
G
S
A
G
H
Y
E
L
P
Site 4
Y34
A
P
G
S
A
G
H
Y
E
L
P
W
V
E
K
Site 5
Y42
E
L
P
W
V
E
K
Y
R
P
V
K
L
N
E
Site 6
T56
E
I
V
G
N
E
D
T
V
S
R
L
E
V
F
Site 7
S58
V
G
N
E
D
T
V
S
R
L
E
V
F
A
R
Site 8
S108
A
M
L
E
L
N
A
S
N
D
R
G
I
D
V
Site 9
S145
I
I
L
D
E
A
D
S
M
T
D
G
A
Q
Q
Site 10
T157
A
Q
Q
A
L
R
R
T
M
E
I
Y
S
K
T
Site 11
Y161
L
R
R
T
M
E
I
Y
S
K
T
T
R
F
A
Site 12
S162
R
R
T
M
E
I
Y
S
K
T
T
R
F
A
L
Site 13
T164
T
M
E
I
Y
S
K
T
T
R
F
A
L
A
C
Site 14
T165
M
E
I
Y
S
K
T
T
R
F
A
L
A
C
N
Site 15
Y190
S
R
C
A
V
L
R
Y
T
K
L
T
D
A
Q
Site 16
T191
R
C
A
V
L
R
Y
T
K
L
T
D
A
Q
I
Site 17
T194
V
L
R
Y
T
K
L
T
D
A
Q
I
L
T
R
Site 18
T200
L
T
D
A
Q
I
L
T
R
L
M
N
V
I
E
Site 19
Y213
I
E
K
E
R
V
P
Y
T
D
D
G
L
E
A
Site 20
T214
E
K
E
R
V
P
Y
T
D
D
G
L
E
A
I
Site 21
S238
Q
A
L
N
N
L
Q
S
T
F
S
G
F
G
F
Site 22
S241
N
N
L
Q
S
T
F
S
G
F
G
F
I
N
S
Site 23
Y279
N
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Site 24
Y311
K
T
F
Q
M
A
E
Y
L
K
L
E
F
I
K
Site 25
T323
F
I
K
E
I
G
Y
T
H
M
K
I
A
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation