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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BMI1
Full Name:
Polycomb complex protein BMI-1
Alias:
BMI1 polycomb ring finger oncogene; MGC12685; PCGF4; Polycomb group RING finger 4; RING finger 51; RNF51
Type:
Mass (Da):
36949
Number AA:
326
UniProt ID:
P35226
International Prot ID:
IPI00017299
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0030097
GO:0048146
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y46
C
K
T
C
I
V
R
Y
L
E
T
S
K
Y
C
Site 2
Y52
R
Y
L
E
T
S
K
Y
C
P
I
C
D
V
Q
Site 3
S71
R
P
L
L
N
I
R
S
D
K
T
L
Q
D
I
Site 4
T74
L
N
I
R
S
D
K
T
L
Q
D
I
V
Y
K
Site 5
Y98
M
K
R
R
R
D
F
Y
A
A
H
P
S
A
D
Site 6
S110
S
A
D
A
A
N
G
S
N
E
D
R
G
E
V
Site 7
T126
D
E
D
K
R
I
I
T
D
D
E
I
I
S
L
Site 8
S134
D
D
E
I
I
S
L
S
I
E
F
F
D
Q
N
Site 9
S154
V
N
K
D
K
E
K
S
K
E
E
V
N
D
K
Site 10
Y163
E
E
V
N
D
K
R
Y
L
R
C
P
A
A
M
Site 11
S181
H
L
R
K
F
L
R
S
K
M
D
I
P
N
T
Site 12
Y195
T
F
Q
I
D
V
M
Y
E
E
E
P
L
K
D
Site 13
Y203
E
E
E
P
L
K
D
Y
Y
T
L
M
D
I
A
Site 14
Y204
E
E
P
L
K
D
Y
Y
T
L
M
D
I
A
Y
Site 15
T205
E
P
L
K
D
Y
Y
T
L
M
D
I
A
Y
I
Site 16
Y211
Y
T
L
M
D
I
A
Y
I
Y
T
W
R
R
N
Site 17
Y213
L
M
D
I
A
Y
I
Y
T
W
R
R
N
G
P
Site 18
Y225
N
G
P
L
P
L
K
Y
R
V
R
P
T
C
K
Site 19
T230
L
K
Y
R
V
R
P
T
C
K
R
M
K
I
S
Site 20
T244
S
H
Q
R
D
G
L
T
N
A
G
E
L
E
S
Site 21
S251
T
N
A
G
E
L
E
S
D
S
G
S
D
K
A
Site 22
S253
A
G
E
L
E
S
D
S
G
S
D
K
A
N
S
Site 23
S255
E
L
E
S
D
S
G
S
D
K
A
N
S
P
A
Site 24
S260
S
G
S
D
K
A
N
S
P
A
G
G
I
P
S
Site 25
S267
S
P
A
G
G
I
P
S
T
S
S
C
L
P
S
Site 26
T268
P
A
G
G
I
P
S
T
S
S
C
L
P
S
P
Site 27
S269
A
G
G
I
P
S
T
S
S
C
L
P
S
P
S
Site 28
S270
G
G
I
P
S
T
S
S
C
L
P
S
P
S
T
Site 29
S274
S
T
S
S
C
L
P
S
P
S
T
P
V
Q
S
Site 30
S276
S
S
C
L
P
S
P
S
T
P
V
Q
S
P
H
Site 31
T277
S
C
L
P
S
P
S
T
P
V
Q
S
P
H
P
Site 32
S281
S
P
S
T
P
V
Q
S
P
H
P
Q
F
P
H
Site 33
S290
H
P
Q
F
P
H
I
S
S
T
M
N
G
T
S
Site 34
S291
P
Q
F
P
H
I
S
S
T
M
N
G
T
S
N
Site 35
T292
Q
F
P
H
I
S
S
T
M
N
G
T
S
N
S
Site 36
S297
S
S
T
M
N
G
T
S
N
S
P
S
G
N
H
Site 37
S299
T
M
N
G
T
S
N
S
P
S
G
N
H
Q
S
Site 38
S301
N
G
T
S
N
S
P
S
G
N
H
Q
S
S
F
Site 39
S306
S
P
S
G
N
H
Q
S
S
F
A
N
R
P
R
Site 40
S307
P
S
G
N
H
Q
S
S
F
A
N
R
P
R
K
Site 41
S315
F
A
N
R
P
R
K
S
S
V
N
G
S
S
A
Site 42
S316
A
N
R
P
R
K
S
S
V
N
G
S
S
A
T
Site 43
S320
R
K
S
S
V
N
G
S
S
A
T
S
S
G
_
Site 44
S321
K
S
S
V
N
G
S
S
A
T
S
S
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation