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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPC1
Full Name:
Glypican-1
Alias:
Type:
Mass (Da):
61680
Number AA:
558
UniProt ID:
P35052
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
C
A
R
G
D
P
A
S
K
S
R
S
C
G
E
Site 2
S29
R
G
D
P
A
S
K
S
R
S
C
G
E
V
R
Site 3
S31
D
P
A
S
K
S
R
S
C
G
E
V
R
Q
I
Site 4
Y39
C
G
E
V
R
Q
I
Y
G
A
K
G
F
S
L
Site 5
S47
G
A
K
G
F
S
L
S
D
V
P
Q
A
E
I
Site 6
Y66
L
R
I
C
P
Q
G
Y
T
C
C
T
S
E
M
Site 7
S92
L
E
T
A
L
R
D
S
S
R
V
L
Q
A
M
Site 8
S93
E
T
A
L
R
D
S
S
R
V
L
Q
A
M
L
Site 9
S118
F
Q
H
L
L
N
D
S
E
R
T
L
Q
A
T
Site 10
T125
S
E
R
T
L
Q
A
T
F
P
G
A
F
G
E
Site 11
Y134
P
G
A
F
G
E
L
Y
T
Q
N
A
R
A
F
Site 12
Y145
A
R
A
F
R
D
L
Y
S
E
L
R
L
Y
Y
Site 13
S146
R
A
F
R
D
L
Y
S
E
L
R
L
Y
Y
R
Site 14
Y151
L
Y
S
E
L
R
L
Y
Y
R
G
A
N
L
H
Site 15
Y152
Y
S
E
L
R
L
Y
Y
R
G
A
N
L
H
L
Site 16
T162
A
N
L
H
L
E
E
T
L
A
E
F
W
A
R
Site 17
Y188
Q
L
L
L
P
D
D
Y
L
D
C
L
G
K
Q
Site 18
T214
R
E
L
R
L
R
A
T
R
A
F
V
A
A
R
Site 19
Y271
G
A
R
P
C
P
D
Y
C
R
N
V
L
K
G
Site 20
S296
E
W
R
N
L
L
D
S
M
V
L
I
T
D
K
Site 21
S308
T
D
K
F
W
G
T
S
G
V
E
S
V
I
G
Site 22
T334
A
L
Q
D
N
R
D
T
L
T
A
K
V
I
Q
Site 23
T336
Q
D
N
R
D
T
L
T
A
K
V
I
Q
G
C
Site 24
S372
A
P
R
E
R
P
P
S
G
T
L
E
K
L
V
Site 25
T374
R
E
R
P
P
S
G
T
L
E
K
L
V
S
E
Site 26
S380
G
T
L
E
K
L
V
S
E
A
K
A
Q
L
R
Site 27
S408
C
S
E
K
M
A
L
S
T
A
S
D
D
R
C
Site 28
S411
K
M
A
L
S
T
A
S
D
D
R
C
W
N
G
Site 29
Y424
N
G
M
A
R
G
R
Y
L
P
E
V
M
G
D
Site 30
T447
P
E
V
E
V
D
I
T
K
P
D
M
T
I
R
Site 31
T464
I
M
Q
L
K
I
M
T
N
R
L
R
S
A
Y
Site 32
S469
I
M
T
N
R
L
R
S
A
Y
N
G
N
D
V
Site 33
Y471
T
N
R
L
R
S
A
Y
N
G
N
D
V
D
F
Site 34
S482
D
V
D
F
Q
D
A
S
D
D
G
S
G
S
G
Site 35
S486
Q
D
A
S
D
D
G
S
G
S
G
S
G
D
G
Site 36
S488
A
S
D
D
G
S
G
S
G
S
G
D
G
C
L
Site 37
S490
D
D
G
S
G
S
G
S
G
D
G
C
L
D
D
Site 38
S504
D
L
C
G
R
K
V
S
R
K
S
S
S
S
R
Site 39
S507
G
R
K
V
S
R
K
S
S
S
S
R
T
P
L
Site 40
S508
R
K
V
S
R
K
S
S
S
S
R
T
P
L
T
Site 41
S509
K
V
S
R
K
S
S
S
S
R
T
P
L
T
H
Site 42
S510
V
S
R
K
S
S
S
S
R
T
P
L
T
H
A
Site 43
T512
R
K
S
S
S
S
R
T
P
L
T
H
A
L
P
Site 44
T515
S
S
S
R
T
P
L
T
H
A
L
P
G
L
S
Site 45
T529
S
E
Q
E
G
Q
K
T
S
A
A
S
C
P
Q
Site 46
S530
E
Q
E
G
Q
K
T
S
A
A
S
C
P
Q
P
Site 47
S533
G
Q
K
T
S
A
A
S
C
P
Q
P
P
T
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation