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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MCM7
Full Name:
DNA replication licensing factor MCM7
Alias:
CDABP0042; CDC47; CDC47 homologue; DNA replication licensing factor MCM7; MCM2; P1CDC47; P85MCM
Type:
DNA replication protein
Mass (Da):
81308
Number AA:
719
UniProt ID:
P33993
International Prot ID:
IPI00299904
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042555
GO:0000785
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005515
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006270
GO:0007049
GO:0042325
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
A
L
K
D
Y
A
L
E
K
E
K
V
Site 2
Y21
K
K
F
L
Q
E
F
Y
Q
D
D
E
L
G
K
Site 3
Y33
L
G
K
K
Q
F
K
Y
G
N
Q
L
V
R
L
Site 4
Y49
H
R
E
Q
V
A
L
Y
V
D
L
D
D
V
A
Site 5
S65
D
D
P
E
L
V
D
S
I
C
E
N
A
R
R
Site 6
Y73
I
C
E
N
A
R
R
Y
A
K
L
F
A
D
A
Site 7
Y88
V
Q
E
L
L
P
Q
Y
K
E
R
E
V
V
N
Site 8
Y102
N
K
D
V
L
D
V
Y
I
E
H
R
L
M
M
Site 9
S113
R
L
M
M
E
Q
R
S
R
D
P
G
M
V
R
Site 10
S121
R
D
P
G
M
V
R
S
P
Q
N
Q
Y
P
A
Site 11
Y126
V
R
S
P
Q
N
Q
Y
P
A
E
L
M
R
R
Site 12
Y137
L
M
R
R
F
E
L
Y
F
Q
G
P
S
S
N
Site 13
S143
L
Y
F
Q
G
P
S
S
N
K
P
R
V
I
R
Site 14
S171
R
G
I
V
T
R
V
S
E
V
K
P
K
M
V
Site 15
S197
E
T
Y
Q
P
I
Q
S
P
T
F
M
P
L
I
Site 16
T213
C
P
S
Q
E
C
Q
T
N
R
S
G
G
R
L
Site 17
Y221
N
R
S
G
G
R
L
Y
L
Q
T
R
G
S
R
Site 18
T224
G
G
R
L
Y
L
Q
T
R
G
S
R
F
I
K
Site 19
S227
L
Y
L
Q
T
R
G
S
R
F
I
K
F
Q
E
Site 20
S241
E
M
K
M
Q
E
H
S
D
Q
V
P
V
G
N
Site 21
T254
G
N
I
P
R
S
I
T
V
L
V
E
G
E
N
Site 22
T262
V
L
V
E
G
E
N
T
R
I
A
Q
P
G
D
Site 23
S294
Q
V
V
Q
G
L
L
S
E
T
Y
L
E
A
H
Site 24
Y297
Q
G
L
L
S
E
T
Y
L
E
A
H
R
I
V
Site 25
S309
R
I
V
K
M
N
K
S
E
D
D
E
S
G
A
Site 26
S314
N
K
S
E
D
D
E
S
G
A
G
E
L
T
R
Site 27
Y333
Q
I
A
E
E
D
F
Y
E
K
L
A
A
S
I
Site 28
S365
L
V
G
G
V
D
Q
S
P
R
G
M
K
I
R
Site 29
S388
G
D
P
G
V
A
K
S
Q
L
L
S
Y
I
D
Site 30
S392
V
A
K
S
Q
L
L
S
Y
I
D
R
L
A
P
Site 31
S401
I
D
R
L
A
P
R
S
Q
Y
T
T
G
R
G
Site 32
Y403
R
L
A
P
R
S
Q
Y
T
T
G
R
G
S
S
Site 33
T404
L
A
P
R
S
Q
Y
T
T
G
R
G
S
S
G
Site 34
T405
A
P
R
S
Q
Y
T
T
G
R
G
S
S
G
V
Site 35
S409
Q
Y
T
T
G
R
G
S
S
G
V
G
L
T
A
Site 36
S410
Y
T
T
G
R
G
S
S
G
V
G
L
T
A
A
Site 37
T456
K
M
A
E
A
D
R
T
A
I
H
E
V
M
E
Site 38
S483
T
T
L
N
A
R
C
S
I
L
A
A
A
N
P
Site 39
Y492
L
A
A
A
N
P
A
Y
G
R
Y
N
P
R
R
Site 40
S500
G
R
Y
N
P
R
R
S
L
E
Q
N
I
Q
L
Site 41
Y539
R
L
A
Q
H
I
T
Y
V
H
Q
H
S
R
Q
Site 42
S544
I
T
Y
V
H
Q
H
S
R
Q
P
P
S
Q
F
Site 43
S549
Q
H
S
R
Q
P
P
S
Q
F
E
P
L
D
M
Site 44
Y562
D
M
K
L
M
R
R
Y
I
A
M
C
R
E
K
Site 45
S576
K
Q
P
M
V
P
E
S
L
A
D
Y
I
T
A
Site 46
Y580
V
P
E
S
L
A
D
Y
I
T
A
A
Y
V
E
Site 47
T582
E
S
L
A
D
Y
I
T
A
A
Y
V
E
M
R
Site 48
Y585
A
D
Y
I
T
A
A
Y
V
E
M
R
R
E
A
Site 49
S595
M
R
R
E
A
W
A
S
K
D
A
T
Y
T
S
Site 50
T599
A
W
A
S
K
D
A
T
Y
T
S
A
R
T
L
Site 51
Y600
W
A
S
K
D
A
T
Y
T
S
A
R
T
L
L
Site 52
S602
S
K
D
A
T
Y
T
S
A
R
T
L
L
A
I
Site 53
S640
A
I
R
L
M
E
M
S
K
D
S
L
L
G
D
Site 54
S643
L
M
E
M
S
K
D
S
L
L
G
D
K
G
Q
Site 55
T654
D
K
G
Q
T
A
R
T
Q
R
P
A
D
V
I
Site 56
S670
A
T
V
R
E
L
V
S
G
G
R
S
V
R
F
Site 57
S674
E
L
V
S
G
G
R
S
V
R
F
S
E
A
E
Site 58
S678
G
G
R
S
V
R
F
S
E
A
E
Q
R
C
V
Site 59
S686
E
A
E
Q
R
C
V
S
R
G
F
T
P
A
Q
Site 60
T690
R
C
V
S
R
G
F
T
P
A
Q
F
Q
A
A
Site 61
Y701
F
Q
A
A
L
D
E
Y
E
E
L
N
V
W
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation