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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GBP1
Full Name:
Interferon-induced guanylate-binding protein 1
Alias:
GBP-1; Guanylate binding protein 1, interferon-inducible, 67kDa; Interferon-gamma inducible protein MAG-1; Interferon-induced guanylate-binding protein 1; MAG-1; MPA1
Type:
G protein; G protein, monomeric (non-Rab)
Mass (Da):
67903
Number AA:
592
UniProt ID:
P32455
International Prot ID:
IPI00028564
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
PhosphoSite+
KinaseNET
Biological Process:
GO:0006955
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
G
L
Y
R
T
G
K
S
Y
L
M
N
K
L
A
Site 2
Y53
L
Y
R
T
G
K
S
Y
L
M
N
K
L
A
G
Site 3
S66
A
G
K
K
K
G
F
S
L
G
S
T
V
Q
S
Site 4
S69
K
K
G
F
S
L
G
S
T
V
Q
S
H
T
K
Site 5
T70
K
G
F
S
L
G
S
T
V
Q
S
H
T
K
G
Site 6
S73
S
L
G
S
T
V
Q
S
H
T
K
G
I
W
M
Site 7
T75
G
S
T
V
Q
S
H
T
K
G
I
W
M
W
C
Site 8
Y143
Q
Q
A
M
D
Q
L
Y
Y
V
T
E
L
T
H
Site 9
Y144
Q
A
M
D
Q
L
Y
Y
V
T
E
L
T
H
R
Site 10
T149
L
Y
Y
V
T
E
L
T
H
R
I
R
S
K
S
Site 11
S154
E
L
T
H
R
I
R
S
K
S
S
P
D
E
N
Site 12
S156
T
H
R
I
R
S
K
S
S
P
D
E
N
E
N
Site 13
S157
H
R
I
R
S
K
S
S
P
D
E
N
E
N
E
Site 14
S168
N
E
N
E
V
E
D
S
A
D
F
V
S
F
F
Site 15
S186
V
W
T
L
R
D
F
S
L
D
L
E
A
D
G
Site 16
T197
E
A
D
G
Q
P
L
T
P
D
E
Y
L
T
Y
Site 17
Y201
Q
P
L
T
P
D
E
Y
L
T
Y
S
L
K
L
Site 18
T203
L
T
P
D
E
Y
L
T
Y
S
L
K
L
K
K
Site 19
Y204
T
P
D
E
Y
L
T
Y
S
L
K
L
K
K
G
Site 20
S205
P
D
E
Y
L
T
Y
S
L
K
L
K
K
G
T
Site 21
S213
L
K
L
K
K
G
T
S
Q
K
D
E
T
F
N
Site 22
T218
G
T
S
Q
K
D
E
T
F
N
L
P
R
L
C
Site 23
S275
D
F
C
S
Y
I
F
S
N
S
K
T
K
T
L
Site 24
S277
C
S
Y
I
F
S
N
S
K
T
K
T
L
S
G
Site 25
T279
Y
I
F
S
N
S
K
T
K
T
L
S
G
G
I
Site 26
T281
F
S
N
S
K
T
K
T
L
S
G
G
I
Q
V
Site 27
Y335
V
Q
K
A
I
A
H
Y
E
Q
Q
M
G
Q
K
Site 28
S349
K
V
Q
L
P
T
E
S
L
Q
E
L
L
D
L
Site 29
S360
L
L
D
L
H
R
D
S
E
R
E
A
I
E
V
Site 30
S371
A
I
E
V
F
I
R
S
S
F
K
D
V
D
H
Site 31
S372
I
E
V
F
I
R
S
S
F
K
D
V
D
H
L
Site 32
S403
C
K
Q
N
Q
E
A
S
S
D
R
C
S
G
L
Site 33
S404
K
Q
N
Q
E
A
S
S
D
R
C
S
G
L
L
Site 34
Y427
E
E
V
K
A
G
I
Y
S
K
P
G
G
Y
R
Site 35
Y447
L
Q
D
L
K
K
K
Y
Y
E
E
P
R
K
G
Site 36
Y448
Q
D
L
K
K
K
Y
Y
E
E
P
R
K
G
I
Site 37
T463
Q
A
E
E
I
L
Q
T
Y
L
K
S
K
E
S
Site 38
Y464
A
E
E
I
L
Q
T
Y
L
K
S
K
E
S
M
Site 39
S467
I
L
Q
T
Y
L
K
S
K
E
S
M
T
D
A
Site 40
T481
A
I
L
Q
T
D
Q
T
L
T
E
K
E
K
E
Site 41
S498
V
E
R
V
K
A
E
S
A
Q
A
S
A
K
M
Site 42
S502
K
A
E
S
A
Q
A
S
A
K
M
L
Q
E
M
Site 43
Y524
M
E
Q
K
E
R
S
Y
Q
E
H
L
K
Q
L
Site 44
T549
L
L
K
E
Q
E
R
T
L
A
L
K
L
Q
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation