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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SDHA
Full Name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Alias:
DHSA; EC 1.3.5.1; Flavoprotein subunit of complex II; Fp; SDH2; SDHF
Type:
Mitochondrial respiratory protein
Mass (Da):
72692
Number AA:
664
UniProt ID:
P31040
International Prot ID:
IPI00305166
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005749
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0009055
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007399
GO:0022904
GO:0006105
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
G
V
R
G
L
S
R
L
L
S
A
R
R
Site 2
T24
A
L
A
K
A
W
P
T
V
L
Q
T
G
T
R
Site 3
T28
A
W
P
T
V
L
Q
T
G
T
R
G
F
H
F
Site 4
T30
P
T
V
L
Q
T
G
T
R
G
F
H
F
T
V
Site 5
T36
G
T
R
G
F
H
F
T
V
D
G
N
K
R
A
Site 6
S44
V
D
G
N
K
R
A
S
A
K
V
S
D
S
I
Site 7
S48
K
R
A
S
A
K
V
S
D
S
I
S
A
Q
Y
Site 8
S50
A
S
A
K
V
S
D
S
I
S
A
Q
Y
P
V
Site 9
S52
A
K
V
S
D
S
I
S
A
Q
Y
P
V
V
D
Site 10
Y55
S
D
S
I
S
A
Q
Y
P
V
V
D
H
E
F
Site 11
S98
T
K
L
F
P
T
R
S
H
T
V
A
A
Q
G
Site 12
T100
L
F
P
T
R
S
H
T
V
A
A
Q
G
G
I
Site 13
Y156
A
V
V
E
L
E
N
Y
G
M
P
F
S
R
T
Site 14
S161
E
N
Y
G
M
P
F
S
R
T
E
D
G
K
I
Site 15
T163
Y
G
M
P
F
S
R
T
E
D
G
K
I
Y
Q
Site 16
Y169
R
T
E
D
G
K
I
Y
Q
R
A
F
G
G
Q
Site 17
S177
Q
R
A
F
G
G
Q
S
L
K
F
G
K
G
G
Site 18
S199
V
A
D
R
T
G
H
S
L
L
H
T
L
Y
G
Site 19
T203
T
G
H
S
L
L
H
T
L
Y
G
R
S
L
R
Site 20
Y205
H
S
L
L
H
T
L
Y
G
R
S
L
R
Y
D
Site 21
S208
L
H
T
L
Y
G
R
S
L
R
Y
D
T
S
Y
Site 22
T213
G
R
S
L
R
Y
D
T
S
Y
F
V
E
Y
F
Site 23
S214
R
S
L
R
Y
D
T
S
Y
F
V
E
Y
F
A
Site 24
Y215
S
L
R
Y
D
T
S
Y
F
V
E
Y
F
A
L
Site 25
S243
A
L
C
I
E
D
G
S
I
H
R
I
R
A
K
Site 26
T252
H
R
I
R
A
K
N
T
V
V
A
T
G
G
Y
Site 27
Y263
T
G
G
Y
G
R
T
Y
F
S
C
T
S
A
H
Site 28
S265
G
Y
G
R
T
Y
F
S
C
T
S
A
H
T
S
Site 29
S268
R
T
Y
F
S
C
T
S
A
H
T
S
T
G
D
Site 30
S272
S
C
T
S
A
H
T
S
T
G
D
G
T
A
M
Site 31
S321
E
G
G
I
L
I
N
S
Q
G
E
R
F
M
E
Site 32
Y330
G
E
R
F
M
E
R
Y
A
P
V
A
K
D
L
Site 33
S339
P
V
A
K
D
L
A
S
R
D
V
V
S
R
S
Site 34
S346
S
R
D
V
V
S
R
S
M
T
L
E
I
R
E
Site 35
T348
D
V
V
S
R
S
M
T
L
E
I
R
E
G
R
Site 36
Y365
G
P
E
K
D
H
V
Y
L
Q
L
H
H
L
P
Site 37
T378
L
P
P
E
Q
L
A
T
R
L
P
G
I
S
E
Site 38
Y417
M
G
G
I
P
T
N
Y
K
G
Q
V
L
R
H
Site 39
Y436
D
Q
I
V
P
G
L
Y
A
C
G
E
A
A
C
Site 40
S456
A
N
R
L
G
A
N
S
L
L
D
L
V
V
F
Site 41
S470
F
G
R
A
C
A
L
S
I
E
E
S
C
R
P
Site 42
S474
C
A
L
S
I
E
E
S
C
R
P
G
D
K
V
Site 43
S492
K
P
N
A
G
E
E
S
V
M
N
L
D
K
L
Site 44
S505
K
L
R
F
A
D
G
S
I
R
T
S
E
L
R
Site 45
S509
A
D
G
S
I
R
T
S
E
L
R
L
S
M
Q
Site 46
S514
R
T
S
E
L
R
L
S
M
Q
K
S
M
Q
N
Site 47
S518
L
R
L
S
M
Q
K
S
M
Q
N
H
A
A
V
Site 48
S530
A
A
V
F
R
V
G
S
V
L
Q
E
G
C
G
Site 49
Y543
C
G
K
I
S
K
L
Y
G
D
L
K
H
L
K
Site 50
T551
G
D
L
K
H
L
K
T
F
D
R
G
M
V
W
Site 51
S588
G
A
E
A
R
K
E
S
R
G
A
H
A
R
E
Site 52
Y597
G
A
H
A
R
E
D
Y
K
V
R
I
D
E
Y
Site 53
Y604
Y
K
V
R
I
D
E
Y
D
Y
S
K
P
I
Q
Site 54
Y606
V
R
I
D
E
Y
D
Y
S
K
P
I
Q
G
Q
Site 55
S607
R
I
D
E
Y
D
Y
S
K
P
I
Q
G
Q
Q
Site 56
T626
E
E
H
W
R
K
H
T
L
S
Y
V
D
V
G
Site 57
Y629
W
R
K
H
T
L
S
Y
V
D
V
G
T
G
K
Site 58
T638
D
V
G
T
G
K
V
T
L
E
Y
R
P
V
I
Site 59
Y641
T
G
K
V
T
L
E
Y
R
P
V
I
D
K
T
Site 60
T648
Y
R
P
V
I
D
K
T
L
N
E
A
D
C
A
Site 61
T656
L
N
E
A
D
C
A
T
V
P
P
A
I
R
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation