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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GTF2E2
Full Name:
Transcription initiation factor IIE subunit beta
Alias:
FE; General transcription factor IIE subunit 2; General transcription factor IIE, polypeptide 2, beta 34kDa; T2EB; TF2E2; TFIIE-B; Transcription initiation factor IIE beta subunit
Type:
Mass (Da):
33044
Number AA:
291
UniProt ID:
P29084
International Prot ID:
IPI00019981
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005673
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003702
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006368
GO:0045449
GO:0006367
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
L
F
K
K
R
A
L
S
T
P
V
V
E
K
R
Site 2
T19
F
K
K
R
A
L
S
T
P
V
V
E
K
R
S
Site 3
S26
T
P
V
V
E
K
R
S
A
S
S
E
S
S
S
Site 4
S28
V
V
E
K
R
S
A
S
S
E
S
S
S
S
S
Site 5
S29
V
E
K
R
S
A
S
S
E
S
S
S
S
S
S
Site 6
S31
K
R
S
A
S
S
E
S
S
S
S
S
S
K
K
Site 7
S32
R
S
A
S
S
E
S
S
S
S
S
S
K
K
K
Site 8
S33
S
A
S
S
E
S
S
S
S
S
S
K
K
K
K
Site 9
S34
A
S
S
E
S
S
S
S
S
S
K
K
K
K
T
Site 10
S35
S
S
E
S
S
S
S
S
S
K
K
K
K
T
K
Site 11
S36
S
E
S
S
S
S
S
S
K
K
K
K
T
K
V
Site 12
T41
S
S
S
K
K
K
K
T
K
V
E
H
G
G
S
Site 13
S48
T
K
V
E
H
G
G
S
S
G
S
K
Q
N
S
Site 14
S49
K
V
E
H
G
G
S
S
G
S
K
Q
N
S
D
Site 15
S51
E
H
G
G
S
S
G
S
K
Q
N
S
D
H
S
Site 16
S55
S
S
G
S
K
Q
N
S
D
H
S
N
G
S
F
Site 17
S58
S
K
Q
N
S
D
H
S
N
G
S
F
N
L
K
Site 18
S61
N
S
D
H
S
N
G
S
F
N
L
K
A
L
S
Site 19
S68
S
F
N
L
K
A
L
S
G
S
S
G
Y
K
F
Site 20
T87
K
I
V
N
Y
M
K
T
R
H
Q
R
G
D
T
Site 21
T94
T
R
H
Q
R
G
D
T
H
P
L
T
L
D
E
Site 22
T98
R
G
D
T
H
P
L
T
L
D
E
I
L
D
E
Site 23
T106
L
D
E
I
L
D
E
T
Q
H
L
D
I
G
L
Site 24
T121
K
Q
K
Q
W
L
M
T
E
A
L
V
N
N
P
Site 25
Y137
I
E
V
I
D
G
K
Y
A
F
K
P
K
Y
N
Site 26
Y143
K
Y
A
F
K
P
K
Y
N
V
R
D
K
K
A
Site 27
S178
I
E
E
A
L
P
N
S
Q
K
A
V
K
A
L
Site 28
S211
N
D
K
S
C
Q
F
S
V
D
E
E
F
Q
K
Site 29
S222
E
F
Q
K
L
W
R
S
V
T
V
D
S
M
D
Site 30
T224
Q
K
L
W
R
S
V
T
V
D
S
M
D
E
E
Site 31
S227
W
R
S
V
T
V
D
S
M
D
E
E
K
I
E
Site 32
Y236
D
E
E
K
I
E
E
Y
L
K
R
Q
G
I
S
Site 33
S244
L
K
R
Q
G
I
S
S
M
Q
E
S
G
P
K
Site 34
S248
G
I
S
S
M
Q
E
S
G
P
K
K
V
A
P
Site 35
S264
Q
R
R
K
K
P
A
S
Q
K
K
R
R
F
K
Site 36
T272
Q
K
K
R
R
F
K
T
H
N
E
H
L
A
G
Site 37
Y284
L
A
G
V
L
K
D
Y
S
D
I
T
S
S
K
Site 38
S285
A
G
V
L
K
D
Y
S
D
I
T
S
S
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation