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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMARCA1
Full Name:
Probable global transcription activator SNF2L1
Alias:
ATP-dependent helicase SMARCA1; EC 3.6.1.-; ISWI; Nucleosome remodeling factor subunit SNF2L; Nucleosome-remodeling factor subunit SNF2L; NURF140; SMCA1
Type:
Chromatin remodeling complex, Cytoplasm, Nucleus protein
Mass (Da):
122605
Number AA:
1054
UniProt ID:
P28370
International Prot ID:
IPI00216046
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0016585
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006325
GO:0006338
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
E
Q
P
G
P
S
T
S
Q
E
E
G
A
A
A
Site 2
S63
K
K
E
K
N
V
S
S
F
Q
L
K
L
A
A
Site 3
S75
L
A
A
K
A
P
K
S
E
K
E
M
D
P
E
Site 4
Y83
E
K
E
M
D
P
E
Y
E
E
K
M
K
A
D
Site 5
T102
F
E
F
L
L
K
Q
T
E
L
F
A
H
F
I
Site 6
S112
F
A
H
F
I
Q
P
S
A
Q
K
S
P
T
S
Site 7
S116
I
Q
P
S
A
Q
K
S
P
T
S
P
L
N
M
Site 8
T118
P
S
A
Q
K
S
P
T
S
P
L
N
M
K
L
Site 9
S119
S
A
Q
K
S
P
T
S
P
L
N
M
K
L
G
Site 10
S137
I
K
K
D
E
K
Q
S
L
I
S
A
G
D
Y
Site 11
S140
D
E
K
Q
S
L
I
S
A
G
D
Y
R
H
R
Site 12
Y144
S
L
I
S
A
G
D
Y
R
H
R
R
T
E
Q
Site 13
T149
G
D
Y
R
H
R
R
T
E
Q
E
E
D
E
E
Site 14
S159
E
E
D
E
E
L
L
S
E
S
R
K
T
S
N
Site 15
T164
L
L
S
E
S
R
K
T
S
N
V
C
I
R
F
Site 16
S165
L
S
E
S
R
K
T
S
N
V
C
I
R
F
E
Site 17
S176
I
R
F
E
V
S
P
S
Y
V
K
G
G
P
L
Site 18
Y177
R
F
E
V
S
P
S
Y
V
K
G
G
P
L
R
Site 19
Y186
K
G
G
P
L
R
D
Y
Q
I
R
G
L
N
W
Site 20
S196
R
G
L
N
W
L
I
S
L
Y
E
N
G
V
N
Site 21
Y228
L
L
G
Y
L
K
H
Y
R
N
I
P
G
P
H
Site 22
Y290
W
D
V
C
V
T
S
Y
E
M
V
I
K
E
K
Site 23
Y307
F
K
K
F
H
W
R
Y
L
V
I
D
E
A
H
Site 24
S321
H
R
I
K
N
E
K
S
K
L
S
E
I
V
R
Site 25
S324
K
N
E
K
S
K
L
S
E
I
V
R
E
F
K
Site 26
S332
E
I
V
R
E
F
K
S
T
N
R
L
L
L
T
Site 27
T333
I
V
R
E
F
K
S
T
N
R
L
L
L
T
G
Site 28
T339
S
T
N
R
L
L
L
T
G
T
P
L
Q
N
N
Site 29
T341
N
R
L
L
L
T
G
T
P
L
Q
N
N
L
H
Site 30
S364
L
L
P
D
V
F
N
S
A
D
D
F
D
S
W
Site 31
T401
F
L
L
R
R
I
K
T
D
V
E
K
S
L
P
Site 32
S406
I
K
T
D
V
E
K
S
L
P
P
K
K
E
I
Site 33
Y416
P
K
K
E
I
K
I
Y
L
G
L
S
K
M
Q
Site 34
S420
I
K
I
Y
L
G
L
S
K
M
Q
R
E
W
Y
Site 35
Y427
S
K
M
Q
R
E
W
Y
T
K
I
L
M
K
D
Site 36
Y464
R
K
C
C
N
H
P
Y
L
F
D
G
A
E
P
Site 37
Y475
G
A
E
P
G
P
P
Y
T
T
D
E
H
I
V
Site 38
S483
T
T
D
E
H
I
V
S
N
S
G
K
M
V
V
Site 39
S503
A
K
L
K
E
Q
G
S
R
V
L
I
F
S
Q
Site 40
S509
G
S
R
V
L
I
F
S
Q
M
T
R
L
L
D
Site 41
Y521
L
L
D
I
L
E
D
Y
C
M
W
R
G
Y
E
Site 42
T536
Y
C
R
L
D
G
Q
T
P
H
E
E
R
E
D
Site 43
Y592
S
A
D
V
V
I
L
Y
D
S
D
W
N
P
Q
Site 44
T624
V
R
V
F
R
L
I
T
D
N
T
V
E
E
R
Site 45
T627
F
R
L
I
T
D
N
T
V
E
E
R
I
V
E
Site 46
S644
E
I
K
L
R
L
D
S
I
V
I
Q
Q
G
R
Site 47
S657
G
R
L
I
D
Q
Q
S
N
K
L
A
K
E
E
Site 48
S679
G
A
T
H
V
F
A
S
K
E
S
E
L
T
D
Site 49
T685
A
S
K
E
S
E
L
T
D
E
D
I
T
T
I
Site 50
T691
L
T
D
E
D
I
T
T
I
L
E
R
G
E
K
Site 51
T700
L
E
R
G
E
K
K
T
A
E
M
N
E
R
L
Site 52
S713
R
L
Q
K
M
G
E
S
S
L
R
N
F
R
M
Site 53
S714
L
Q
K
M
G
E
S
S
L
R
N
F
R
M
D
Site 54
S725
F
R
M
D
I
E
Q
S
L
Y
K
F
E
G
E
Site 55
Y727
M
D
I
E
Q
S
L
Y
K
F
E
G
E
D
Y
Site 56
Y734
Y
K
F
E
G
E
D
Y
R
E
K
Q
K
L
G
Site 57
Y762
A
N
Y
A
V
D
A
Y
F
R
E
A
L
R
V
Site 58
S770
F
R
E
A
L
R
V
S
E
P
K
I
P
K
A
Site 59
Y806
L
L
E
K
E
I
L
Y
Y
R
K
T
I
G
Y
Site 60
Y807
L
E
K
E
I
L
Y
Y
R
K
T
I
G
Y
K
Site 61
T810
E
I
L
Y
Y
R
K
T
I
G
Y
K
V
P
R
Site 62
Y813
Y
Y
R
K
T
I
G
Y
K
V
P
R
N
P
D
Site 63
T842
I
D
G
A
E
P
L
T
P
E
E
T
E
E
K
Site 64
T854
E
E
K
E
K
L
L
T
Q
G
F
T
N
W
T
Site 65
Y875
F
I
K
A
N
E
K
Y
G
R
D
D
I
D
N
Site 66
S891
A
R
E
V
E
G
K
S
P
E
E
V
M
E
Y
Site 67
Y898
S
P
E
E
V
M
E
Y
S
A
V
F
W
E
R
Site 68
S931
A
R
I
Q
R
R
I
S
I
K
K
A
L
D
A
Site 69
Y943
L
D
A
K
I
A
R
Y
K
A
P
F
H
Q
L
Site 70
Y954
F
H
Q
L
R
I
Q
Y
G
T
S
K
G
K
N
Site 71
T956
Q
L
R
I
Q
Y
G
T
S
K
G
K
N
Y
T
Site 72
Y985
G
F
D
R
E
N
V
Y
E
E
L
R
Q
C
V
Site 73
T1018
E
F
Q
R
R
C
N
T
L
I
S
L
I
E
K
Site 74
S1021
R
R
C
N
T
L
I
S
L
I
E
K
E
N
M
Site 75
T1043
A
E
K
K
K
R
A
T
K
T
P
M
V
K
F
Site 76
T1045
K
K
K
R
A
T
K
T
P
M
V
K
F
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation