PhosphoNET

           
Protein Info 
   
Short Name:  PSMB4
Full Name:  Proteasome subunit beta type-4
Alias:  HN3; HSN3; Macropain beta chain; Multicatalytic endopeptidase complex beta; PROS26; Proteasome (prosome, macropain) subunit, beta type, 4; Proteasome beta chain; Proteasome chain 3; Proteasome component N3; Proteasome subunit beta type 4; PSB4
Type:  Protease; EC 3.4.25.1; Proteasome complex
Mass (Da):  29204
Number AA:  264
UniProt ID:  P28070
International Prot ID:  IPI00555956
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005813  GO:0005634  GO:0005839 Uniprot OncoNet
Molecular Function:  GO:0004298     PhosphoSite+ KinaseNET
Biological Process:  GO:0031145  GO:0051436  GO:0051437 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9EAFLGSRSGLWAGGP
Site 2Y22GPAPGQFYRIPSTPD
Site 3S26GQFYRIPSTPDSFMD
Site 4T27QFYRIPSTPDSFMDP
Site 5S30RIPSTPDSFMDPASA
Site 6S36DSFMDPASALYRGPI
Site 7Y39MDPASALYRGPITRT
Site 8T44ALYRGPITRTQNPMV
Site 9T46YRGPITRTQNPMVTG
Site 10T54QNPMVTGTSVLGVKF
Site 11S55NPMVTGTSVLGVKFE
Site 12Y75AADMLGSYGSLARFR
Site 13S77DMLGSYGSLARFRNI
Site 14S85LARFRNISRIMRVNN
Site 15T94IMRVNNSTMLGASGD
Site 16Y102MLGASGDYADFQYLK
Site 17Y107GDYADFQYLKQVLGQ
Site 18S127ELLGDGHSYSPRAIH
Site 19Y128LLGDGHSYSPRAIHS
Site 20S129LGDGHSYSPRAIHSW
Site 21T138RAIHSWLTRAMYSRR
Site 22Y142SWLTRAMYSRRSKMN
Site 23S165GGYADGESFLGYVDM
Site 24Y186APSLATGYGAYLAQP
Site 25Y189LATGYGAYLAQPLLR
Site 26S206LEKQPVLSQTEARDL
Site 27T208KQPVLSQTEARDLVE
Site 28Y222ERCMRVLYYRDARSY
Site 29Y223RCMRVLYYRDARSYN
Site 30Y229YYRDARSYNRFQIAT
Site 31T236YNRFQIATVTEKGVE
Site 32S249VEIEGPLSTETNWDI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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