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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AOAH
Full Name:
Acyloxyacyl hydrolase
Alias:
Type:
Mass (Da):
65105
Number AA:
575
UniProt ID:
P28039
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
L
L
L
S
L
Q
S
S
A
S
P
A
N
D
D
Site 2
S24
L
S
L
Q
S
S
A
S
P
A
N
D
D
Q
S
Site 3
S31
S
P
A
N
D
D
Q
S
R
P
S
L
S
N
G
Site 4
S34
N
D
D
Q
S
R
P
S
L
S
N
G
H
T
C
Site 5
S36
D
Q
S
R
P
S
L
S
N
G
H
T
C
V
G
Site 6
T61
L
A
Q
V
H
N
S
T
V
Q
A
S
M
E
R
Site 7
S71
A
S
M
E
R
L
C
S
Y
L
P
E
K
L
F
Site 8
Y126
G
Q
P
L
C
H
L
Y
P
L
P
K
E
T
W
Site 9
T132
L
Y
P
L
P
K
E
T
W
K
F
T
L
Q
K
Site 10
S147
A
R
Q
I
V
K
K
S
P
I
L
K
Y
S
R
Site 11
Y152
K
K
S
P
I
L
K
Y
S
R
S
G
S
D
I
Site 12
S153
K
S
P
I
L
K
Y
S
R
S
G
S
D
I
C
Site 13
S155
P
I
L
K
Y
S
R
S
G
S
D
I
C
S
L
Site 14
S157
L
K
Y
S
R
S
G
S
D
I
C
S
L
P
V
Site 15
S179
I
K
L
A
M
E
Q
S
V
P
F
K
D
V
D
Site 16
S187
V
P
F
K
D
V
D
S
D
K
Y
S
V
F
P
Site 17
Y190
K
D
V
D
S
D
K
Y
S
V
F
P
T
L
R
Site 18
S191
D
V
D
S
D
K
Y
S
V
F
P
T
L
R
G
Site 19
Y199
V
F
P
T
L
R
G
Y
H
W
R
G
R
D
C
Site 20
S209
R
G
R
D
C
N
D
S
D
E
S
V
Y
P
G
Site 21
S212
D
C
N
D
S
D
E
S
V
Y
P
G
R
R
P
Site 22
Y214
N
D
S
D
E
S
V
Y
P
G
R
R
P
N
N
Site 23
Y244
D
P
K
D
G
V
P
Y
E
K
K
F
C
E
G
Site 24
S252
E
K
K
F
C
E
G
S
Q
P
R
G
I
I
L
Site 25
S271
A
G
A
H
F
H
I
S
P
E
W
I
T
A
S
Site 26
S278
S
P
E
W
I
T
A
S
Q
M
S
L
N
S
F
Site 27
S302
E
L
D
W
P
Q
L
S
G
A
T
G
F
L
D
Site 28
S310
G
A
T
G
F
L
D
S
T
V
G
I
K
E
K
Site 29
T311
A
T
G
F
L
D
S
T
V
G
I
K
E
K
S
Site 30
S318
T
V
G
I
K
E
K
S
I
Y
L
R
L
W
K
Site 31
Y320
G
I
K
E
K
S
I
Y
L
R
L
W
K
R
N
Site 32
Y334
N
H
C
N
H
R
D
Y
Q
N
I
S
R
N
G
Site 33
S338
H
R
D
Y
Q
N
I
S
R
N
G
A
S
S
R
Site 34
S343
N
I
S
R
N
G
A
S
S
R
N
L
K
K
F
Site 35
S344
I
S
R
N
G
A
S
S
R
N
L
K
K
F
I
Site 36
S353
N
L
K
K
F
I
E
S
L
S
R
N
K
V
L
Site 37
S355
K
K
F
I
E
S
L
S
R
N
K
V
L
D
Y
Site 38
S377
M
I
G
N
D
V
C
S
G
K
S
D
P
V
P
Site 39
S380
N
D
V
C
S
G
K
S
D
P
V
P
A
M
T
Site 40
T387
S
D
P
V
P
A
M
T
T
P
E
K
L
Y
S
Site 41
T388
D
P
V
P
A
M
T
T
P
E
K
L
Y
S
N
Site 42
S394
T
T
P
E
K
L
Y
S
N
V
M
Q
T
L
K
Site 43
S405
Q
T
L
K
H
L
N
S
H
L
P
N
G
S
H
Site 44
S411
N
S
H
L
P
N
G
S
H
V
I
L
Y
G
L
Site 45
T443
G
Q
L
N
K
D
M
T
Y
A
Q
L
Y
S
F
Site 46
Y444
Q
L
N
K
D
M
T
Y
A
Q
L
Y
S
F
L
Site 47
T468
G
W
M
S
S
N
K
T
L
R
T
L
T
S
E
Site 48
T473
N
K
T
L
R
T
L
T
S
E
R
A
E
Q
L
Site 49
S474
K
T
L
R
T
L
T
S
E
R
A
E
Q
L
S
Site 50
S481
S
E
R
A
E
Q
L
S
N
T
L
K
K
I
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation