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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GIF
Full Name:
Gastric intrinsic factor
Alias:
Intrinsic factor
Type:
Mass (Da):
45416
Number AA:
417
UniProt ID:
P27352
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
W
A
T
A
G
T
S
T
Q
T
Q
S
S
C
S
Site 2
S24
G
T
S
T
Q
T
Q
S
S
C
S
V
P
S
A
Site 3
S25
T
S
T
Q
T
Q
S
S
C
S
V
P
S
A
Q
Site 4
S27
T
Q
T
Q
S
S
C
S
V
P
S
A
Q
E
P
Site 5
T48
V
L
M
E
N
S
V
T
S
S
A
Y
P
N
P
Site 6
S50
M
E
N
S
V
T
S
S
A
Y
P
N
P
S
I
Site 7
Y52
N
S
V
T
S
S
A
Y
P
N
P
S
I
L
I
Site 8
T76
L
K
A
Q
K
L
L
T
Y
Q
L
M
S
S
D
Site 9
Y77
K
A
Q
K
L
L
T
Y
Q
L
M
S
S
D
N
Site 10
S82
L
T
Y
Q
L
M
S
S
D
N
N
D
L
T
I
Site 11
T88
S
S
D
N
N
D
L
T
I
G
Q
L
G
L
T
Site 12
S101
L
T
I
M
A
L
T
S
S
C
R
D
P
G
D
Site 13
S102
T
I
M
A
L
T
S
S
C
R
D
P
G
D
K
Site 14
S111
R
D
P
G
D
K
V
S
I
L
Q
R
Q
M
E
Site 15
S124
M
E
N
W
A
P
S
S
P
N
A
E
A
S
A
Site 16
S130
S
S
P
N
A
E
A
S
A
F
Y
G
P
S
L
Site 17
S166
K
T
L
L
A
N
S
S
P
F
N
V
D
T
G
Site 18
Y195
P
V
G
S
E
E
G
Y
R
S
L
F
G
Q
V
Site 19
S197
G
S
E
E
G
Y
R
S
L
F
G
Q
V
L
K
Site 20
S234
G
L
A
M
Q
A
L
S
V
T
P
E
P
S
K
Site 21
T236
A
M
Q
A
L
S
V
T
P
E
P
S
K
K
E
Site 22
S267
G
K
F
H
N
P
M
S
I
A
Q
I
L
P
S
Site 23
Y280
P
S
L
K
G
K
T
Y
L
D
V
P
Q
V
T
Site 24
T287
Y
L
D
V
P
Q
V
T
C
S
P
D
H
E
V
Site 25
S289
D
V
P
Q
V
T
C
S
P
D
H
E
V
Q
P
Site 26
T297
P
D
H
E
V
Q
P
T
L
P
S
N
P
G
P
Site 27
S300
E
V
Q
P
T
L
P
S
N
P
G
P
G
P
T
Site 28
S308
N
P
G
P
G
P
T
S
A
S
N
I
T
V
I
Site 29
T317
S
N
I
T
V
I
Y
T
I
N
N
Q
L
R
G
Site 30
Y385
E
N
V
N
H
K
T
Y
W
Q
F
L
S
G
V
Site 31
S390
K
T
Y
W
Q
F
L
S
G
V
T
P
L
N
E
Site 32
Y402
L
N
E
G
V
A
D
Y
I
P
F
N
H
E
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation