PhosphoNET

           
Protein Info 
   
Short Name:  ZFP36
Full Name:  Tristetraprolin
Alias:  G0/G1 switch regulatory protein 24; G0S24; Growth factor-inducible nuclear protein NUP475; NUP475; RNF162A; TIS11; TIS11A; TIS11A protein; Tristetraprolin; Zfp-36; Zinc finger protein 36 homolog; Zinc finger protein 36, C3H type,
Type:  RNA binding protein; DNA binding protein
Mass (Da):  34003
Number AA:  326
UniProt ID:  P26651
International Prot ID:  IPI00000893
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0003729  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006402     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9DLTAIYESLLSLSPD
Site 2S12AIYESLLSLSPDVPV
Site 3S14YESLLSLSPDVPVPS
Site 4S21SPDVPVPSDHGGTES
Site 5T26VPSDHGGTESSPGWG
Site 6S28SDHGGTESSPGWGSS
Site 7S29DHGGTESSPGWGSSG
Site 8S34ESSPGWGSSGPWSLS
Site 9S35SSPGWGSSGPWSLSP
Site 10S39WGSSGPWSLSPSDSS
Site 11S41SSGPWSLSPSDSSPS
Site 12S43GPWSLSPSDSSPSGV
Site 13S45WSLSPSDSSPSGVTS
Site 14S46SLSPSDSSPSGVTSR
Site 15S48SPSDSSPSGVTSRLP
Site 16S52SSPSGVTSRLPGRST
Site 17S58TSRLPGRSTSLVEGR
Site 18T59SRLPGRSTSLVEGRS
Site 19S60RLPGRSTSLVEGRSC
Site 20S66TSLVEGRSCGWVPPP
Site 21S88PRLGPELSPSPTSPT
Site 22S90LGPELSPSPTSPTAT
Site 23T92PELSPSPTSPTATST
Site 24S93ELSPSPTSPTATSTT
Site 25T95SPSPTSPTATSTTPS
Site 26T97SPTSPTATSTTPSRY
Site 27S98PTSPTATSTTPSRYK
Site 28T100SPTATSTTPSRYKTE
Site 29S102TATSTTPSRYKTELC
Site 30T106TTPSRYKTELCRTFS
Site 31T111YKTELCRTFSESGRC
Site 32S113TELCRTFSESGRCRY
Site 33S115LCRTFSESGRCRYGA
Site 34Y120SESGRCRYGAKCQFA
Site 35Y142QANRHPKYKTELCHK
Site 36T144NRHPKYKTELCHKFY
Site 37Y151TELCHKFYLQGRCPY
Site 38Y158YLQGRCPYGSRCHFI
Site 39S160QGRCPYGSRCHFIHN
Site 40S169CHFIHNPSEDLAAPG
Site 41S184HPPVLRQSISFSGLP
Site 42S186PVLRQSISFSGLPSG
Site 43S188LRQSISFSGLPSGRR
Site 44S192ISFSGLPSGRRTSPP
Site 45T196GLPSGRRTSPPPPGL
Site 46S197LPSGRRTSPPPPGLA
Site 47S207PPGLAGPSLSSSSFS
Site 48S209GLAGPSLSSSSFSPS
Site 49S210LAGPSLSSSSFSPSS
Site 50S211AGPSLSSSSFSPSSS
Site 51S212GPSLSSSSFSPSSSP
Site 52S214SLSSSSFSPSSSPPP
Site 53S216SSSSFSPSSSPPPPG
Site 54S217SSSFSPSSSPPPPGD
Site 55S218SSFSPSSSPPPPGDL
Site 56S228PPGDLPLSPSAFSAA
Site 57S230GDLPLSPSAFSAAPG
Site 58S233PLSPSAFSAAPGTPL
Site 59T238AFSAAPGTPLARRDP
Site 60T246PLARRDPTPVCCPSC
Site 61S252PTPVCCPSCRRATPI
Site 62T257CPSCRRATPISVWGP
Site 63S260CRRATPISVWGPLGG
Site 64T271PLGGLVRTPSVQSLG
Site 65S273GGLVRTPSVQSLGSD
Site 66S276VRTPSVQSLGSDPDE
Site 67S279PSVQSLGSDPDEYAS
Site 68Y284LGSDPDEYASSGSSL
Site 69S286SDPDEYASSGSSLGG
Site 70S287DPDEYASSGSSLGGS
Site 71S290EYASSGSSLGGSDSP
Site 72S294SGSSLGGSDSPVFEA
Site 73S296SSLGGSDSPVFEAGV
Site 74S323LPIFNRISVSE____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation