PhosphoNET

           
Protein Info 
   
Short Name:  Pax6
Full Name:  Paired box protein Pax-6
Alias:  AN2; Aniridia type II protein; Oculorhombin
Type:  Transcription protein
Mass (Da):  46683
Number AA:  422
UniProt ID:  P26367
International Prot ID:  IPI00218800
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0043565  GO:0003700 PhosphoSite+ KinaseNET
Biological Process:  GO:0007417  GO:0001654  GO:0048663 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S24NGRPLPDSTRQKIVE
Site 2T25GRPLPDSTRQKIVEL
Site 3S35KIVELAHSGARPCDI
Site 4S43GARPCDISRILQVSN
Site 5Y60VSKILGRYYETGSIR
Site 6Y61SKILGRYYETGSIRP
Site 7S65GRYYETGSIRPRAIG
Site 8S74RPRAIGGSKPRVATP
Site 9T80GSKPRVATPEVVSKI
Site 10Y90VVSKIAQYKRECPSI
Site 11S108EIRDRLLSEGVCTND
Site 12S119CTNDNIPSVSSINRV
Site 13S132RVLRNLASEKQQMGA
Site 14Y143QMGADGMYDKLRMLN
Site 15Y163WGTRPGWYPGTSVPG
Site 16T166RPGWYPGTSVPGQPT
Site 17S167PGWYPGTSVPGQPTQ
Site 18T187QEGGGENTNSISSNG
Site 19S189GGGENTNSISSNGED
Site 20S191GENTNSISSNGEDSD
Site 21S197ISSNGEDSDEAQMRL
Site 22T215RKLQRNRTSFTQEQI
Site 23S216KLQRNRTSFTQEQIE
Site 24T232LEKEFERTHYPDVFA
Site 25Y234KEFERTHYPDVFARE
Site 26S279RNQRRQASNTPSHIP
Site 27T281QRRQASNTPSHIPIS
Site 28S283RQASNTPSHIPISSS
Site 29S288TPSHIPISSSFSTSV
Site 30S289PSHIPISSSFSTSVY
Site 31S290SHIPISSSFSTSVYQ
Site 32T293PISSSFSTSVYQPIP
Site 33S294ISSSFSTSVYQPIPQ
Site 34Y296SSFSTSVYQPIPQPT
Site 35T303YQPIPQPTTPVSSFT
Site 36T304QPIPQPTTPVSSFTS
Site 37S307PQPTTPVSSFTSGSM
Site 38S308QPTTPVSSFTSGSML
Site 39S311TPVSSFTSGSMLGRT
Site 40S313VSSFTSGSMLGRTDT
Site 41T318SGSMLGRTDTALTNT
Site 42T320SMLGRTDTALTNTYS
Site 43T323GRTDTALTNTYSALP
Site 44S327TALTNTYSALPPMPS
Site 45S349PMQPPVPSQTSSYSC
Site 46T351QPPVPSQTSSYSCML
Site 47S352PPVPSQTSSYSCMLP
Site 48S353PVPSQTSSYSCMLPT
Site 49S355PSQTSSYSCMLPTSP
Site 50S361YSCMLPTSPSVNGRS
Site 51S363CMLPTSPSVNGRSYD
Site 52S368SPSVNGRSYDTYTPP
Site 53Y369PSVNGRSYDTYTPPH
Site 54T371VNGRSYDTYTPPHMQ
Site 55Y372NGRSYDTYTPPHMQT
Site 56T373GRSYDTYTPPHMQTH
Site 57S389NSQPMGTSGTTSTGL
Site 58S393MGTSGTTSTGLISPG
Site 59S410VPVQVPGSEPDMSQY
Site 60S415PGSEPDMSQYWPRLQ
Site 61Y417SEPDMSQYWPRLQ__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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