KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CTNNA2
Full Name:
Catenin alpha-2
Alias:
Alpha N-catenin; Alpha-2 catenin; Alpha-catenin-related protein; Cadherin-associated protein, related; CAPR; CAP-R; Catenin, alpha 2; CTN2; CTNA2
Type:
Cytoskeletal protein
Mass (Da):
105313
Number AA:
953
UniProt ID:
P26232
International Prot ID:
IPI00385055
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0030424
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0045296
GO:0005200
PhosphoSite+
KinaseNET
Biological Process:
GO:0007409
GO:0048854
GO:0016337
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
T
S
A
T
S
P
I
I
L
K
W
Site 2
S6
_
_
M
T
S
A
T
S
P
I
I
L
K
W
D
Site 3
S16
I
L
K
W
D
P
K
S
L
E
I
R
T
L
T
Site 4
T23
S
L
E
I
R
T
L
T
V
E
R
L
L
E
P
Site 5
T102
D
V
R
K
Q
G
E
T
M
R
I
A
S
S
E
Site 6
S107
G
E
T
M
R
I
A
S
S
E
F
A
D
D
P
Site 7
S116
E
F
A
D
D
P
C
S
S
V
K
R
G
T
M
Site 8
S117
F
A
D
D
P
C
S
S
V
K
R
G
T
M
V
Site 9
T122
C
S
S
V
K
R
G
T
M
V
R
A
A
R
A
Site 10
S132
R
A
A
R
A
L
L
S
A
V
T
R
L
L
I
Site 11
T135
R
A
L
L
S
A
V
T
R
L
L
I
L
A
D
Site 12
S151
A
D
V
M
R
L
L
S
H
L
K
I
V
E
E
Site 13
Y188
K
E
M
V
K
L
N
Y
V
A
A
R
R
Q
Q
Site 14
Y221
K
K
N
A
T
M
L
Y
T
A
S
Q
A
F
L
Site 15
S224
A
T
M
L
Y
T
A
S
Q
A
F
L
R
H
P
Site 16
Y242
A
T
R
A
N
R
D
Y
V
F
K
Q
V
Q
E
Site 17
T261
I
S
N
A
A
Q
A
T
S
P
T
D
E
A
K
Site 18
S262
S
N
A
A
Q
A
T
S
P
T
D
E
A
K
G
Site 19
T293
K
I
I
L
D
P
M
T
F
S
E
A
R
F
R
Site 20
S295
I
L
D
P
M
T
F
S
E
A
R
F
R
P
S
Site 21
S302
S
E
A
R
F
R
P
S
L
E
E
R
L
E
S
Site 22
S321
A
A
L
M
A
D
S
S
C
T
R
D
D
R
R
Site 23
S347
Q
A
L
Q
D
L
L
S
E
Y
M
N
N
T
G
Site 24
Y349
L
Q
D
L
L
S
E
Y
M
N
N
T
G
R
K
Site 25
S389
K
A
V
M
D
H
I
S
D
S
F
L
E
T
N
Site 26
S391
V
M
D
H
I
S
D
S
F
L
E
T
N
V
P
Site 27
S408
V
L
I
E
A
A
K
S
G
N
E
K
E
V
K
Site 28
Y417
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Site 29
S439
A
N
L
A
C
S
I
S
N
N
E
E
G
V
K
Site 30
S475
T
L
A
A
R
P
Q
S
K
V
A
Q
D
N
M
Site 31
T497
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Site 32
T504
T
E
A
V
D
D
I
T
S
V
D
D
F
L
S
Site 33
S513
V
D
D
F
L
S
V
S
E
N
H
I
L
E
D
Site 34
T535
L
Q
E
G
D
V
D
T
L
D
R
T
A
G
A
Site 35
T539
D
V
D
T
L
D
R
T
A
G
A
I
R
G
R
Site 36
Y561
I
N
A
E
M
E
N
Y
E
A
G
V
Y
T
E
Site 37
Y566
E
N
Y
E
A
G
V
Y
T
E
K
V
L
E
A
Site 38
T580
A
T
K
L
L
S
E
T
V
M
P
R
F
A
E
Site 39
Y617
I
D
A
S
R
L
V
Y
D
G
V
R
D
I
R
Site 40
T632
K
A
V
L
M
I
R
T
P
E
E
L
E
D
D
Site 41
S640
P
E
E
L
E
D
D
S
D
F
E
Q
E
D
Y
Site 42
Y647
S
D
F
E
Q
E
D
Y
D
V
R
S
R
T
S
Site 43
S651
Q
E
D
Y
D
V
R
S
R
T
S
V
Q
T
E
Site 44
T653
D
Y
D
V
R
S
R
T
S
V
Q
T
E
D
D
Site 45
S654
Y
D
V
R
S
R
T
S
V
Q
T
E
D
D
Q
Site 46
T657
R
S
R
T
S
V
Q
T
E
D
D
Q
L
I
A
Site 47
S667
D
Q
L
I
A
G
Q
S
A
R
A
I
M
A
Q
Site 48
S707
E
V
A
K
W
D
D
S
G
N
D
I
I
V
L
Site 49
T729
M
M
E
M
T
D
F
T
R
G
K
G
P
L
K
Site 50
S753
K
K
I
A
E
A
G
S
R
M
D
K
L
A
R
Site 51
S769
V
A
D
Q
C
P
D
S
A
C
K
Q
D
L
L
Site 52
Y778
C
K
Q
D
L
L
A
Y
L
Q
R
I
A
L
Y
Site 53
T816
S
G
T
G
V
Q
S
T
F
T
T
F
Y
E
V
Site 54
S834
V
I
D
G
G
R
A
S
Q
L
S
T
H
L
P
Site 55
S837
G
G
R
A
S
Q
L
S
T
H
L
P
T
C
A
Site 56
T838
G
R
A
S
Q
L
S
T
H
L
P
T
C
A
E
Site 57
S851
A
E
G
A
P
I
G
S
G
S
S
D
S
S
M
Site 58
S853
G
A
P
I
G
S
G
S
S
D
S
S
M
L
D
Site 59
S854
A
P
I
G
S
G
S
S
D
S
S
M
L
D
S
Site 60
S856
I
G
S
G
S
S
D
S
S
M
L
D
S
A
T
Site 61
S857
G
S
G
S
S
D
S
S
M
L
D
S
A
T
S
Site 62
S861
S
D
S
S
M
L
D
S
A
T
S
L
I
Q
A
Site 63
S864
S
M
L
D
S
A
T
S
L
I
Q
A
A
K
N
Site 64
S887
V
K
A
S
Y
V
A
S
T
K
Y
Q
K
V
Y
Site 65
Y890
S
Y
V
A
S
T
K
Y
Q
K
V
Y
G
T
A
Site 66
Y894
S
T
K
Y
Q
K
V
Y
G
T
A
A
V
N
S
Site 67
T896
K
Y
Q
K
V
Y
G
T
A
A
V
N
S
P
V
Site 68
S901
Y
G
T
A
A
V
N
S
P
V
V
S
W
K
M
Site 69
S905
A
V
N
S
P
V
V
S
W
K
M
K
A
P
E
Site 70
T927
E
K
P
E
E
F
Q
T
R
V
R
R
G
S
Q
Site 71
S933
Q
T
R
V
R
R
G
S
Q
K
K
H
I
S
P
Site 72
S939
G
S
Q
K
K
H
I
S
P
V
Q
A
L
S
E
Site 73
S945
I
S
P
V
Q
A
L
S
E
F
K
A
M
D
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation