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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMA1
Full Name:
Proteasome subunit alpha type-1
Alias:
30 kDa prosomal protein; EC 3.4.25.1; HC2; Macropain subunit nu; Multicatalytic endopeptidase complex subunit C2; NU, PROS30; Proteasome (prosome, macropain) subunit, alpha type, 1; Proteasome alpha 1 subunit; Proteasome component C2; Proteasome nu chain; Proteasome subunit nu; Protein P30-33K; PSA1
Type:
Protease, Proteasome complex
Mass (Da):
29556
Number AA:
263
UniProt ID:
P25786
International Prot ID:
IPI00472442
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005844
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
GO:0004298
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051436
GO:0051437
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
D
N
D
V
T
V
W
S
P
Q
G
R
I
H
Q
Site 2
T35
A
V
K
Q
G
S
A
T
V
G
L
K
S
K
T
Site 3
S40
S
A
T
V
G
L
K
S
K
T
H
A
V
L
V
Site 4
T42
T
V
G
L
K
S
K
T
H
A
V
L
V
A
L
Site 5
S54
V
A
L
K
R
A
Q
S
E
L
A
A
H
Q
K
Site 6
S95
M
R
Q
E
C
L
D
S
R
F
V
F
D
R
P
Site 7
S110
L
P
V
S
R
L
V
S
L
I
G
S
K
T
Q
Site 8
S114
R
L
V
S
L
I
G
S
K
T
Q
I
P
T
Q
Site 9
T116
V
S
L
I
G
S
K
T
Q
I
P
T
Q
R
Y
Site 10
T120
G
S
K
T
Q
I
P
T
Q
R
Y
G
R
R
P
Site 11
Y123
T
Q
I
P
T
Q
R
Y
G
R
R
P
Y
G
V
Site 12
Y128
Q
R
Y
G
R
R
P
Y
G
V
G
L
L
I
A
Site 13
Y137
V
G
L
L
I
A
G
Y
D
D
M
G
P
H
I
Site 14
S150
H
I
F
Q
T
C
P
S
A
N
Y
F
D
C
R
Site 15
Y153
Q
T
C
P
S
A
N
Y
F
D
C
R
A
M
S
Site 16
S160
Y
F
D
C
R
A
M
S
I
G
A
R
S
Q
S
Site 17
S165
A
M
S
I
G
A
R
S
Q
S
A
R
T
Y
L
Site 18
S167
S
I
G
A
R
S
Q
S
A
R
T
Y
L
E
R
Site 19
Y171
R
S
Q
S
A
R
T
Y
L
E
R
H
M
S
E
Site 20
S177
T
Y
L
E
R
H
M
S
E
F
M
E
C
N
L
Site 21
T198
G
L
R
A
L
R
E
T
L
P
A
E
Q
D
L
Site 22
T206
L
P
A
E
Q
D
L
T
T
K
N
V
S
I
G
Site 23
T207
P
A
E
Q
D
L
T
T
K
N
V
S
I
G
I
Site 24
S211
D
L
T
T
K
N
V
S
I
G
I
V
G
K
D
Site 25
Y224
K
D
L
E
F
T
I
Y
D
D
D
D
V
S
P
Site 26
S230
I
Y
D
D
D
D
V
S
P
F
L
E
G
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation