PhosphoNET

           
Protein Info 
   
Short Name:  BRD2
Full Name:  Bromodomain-containing protein 2
Alias:  KIAA9001; O27.1.1; Protein RING3; RING3
Type:  Protein kinase, Ser/Thr (non-receptor); ATYPICAL group; BRD family
Mass (Da):  88061
Number AA:  801
UniProt ID:  P25440
International Prot ID:  IPI00014414
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0004674     PhosphoSite+ KinaseNET
Biological Process:  GO:0007283     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T6__MLQNVTPHNKLPG
Site 2S37GKRIRKPSLLYEGFE
Site 3Y40IRKPSLLYEGFESPT
Site 4S45LLYEGFESPTMASVP
Site 5T47YEGFESPTMASVPAL
Site 6S50FESPTMASVPALQLT
Site 7T57SVPALQLTPANPPPP
Site 8S67NPPPPEVSNPKKPGR
Site 9T76PKKPGRVTNQLQYLH
Site 10Y81RVTNQLQYLHKVVMK
Site 11Y113VKLGLPDYHKIIKQP
Site 12T125KQPMDMGTIKRRLEN
Site 13Y134KRRLENNYYWAASEC
Site 14Y135RRLENNYYWAASECM
Site 15S179IFLQKVASMPQEEQE
Site 16T190EEQELVVTIPKNSHK
Site 17T224AVSSVSHTALYTPPP
Site 18Y227SVSHTALYTPPPEIP
Site 19T228VSHTALYTPPPEIPT
Site 20T236PPPEIPTTVLNIPHP
Site 21S248PHPSVISSPLLKSLH
Site 22S253ISSPLLKSLHSAGPP
Site 23T285GVKRKADTTTPTPTA
Site 24T286VKRKADTTTPTPTAI
Site 25T287KRKADTTTPTPTAIL
Site 26T289KADTTTPTPTAILAP
Site 27T291DTTTPTPTAILAPGS
Site 28S298TAILAPGSPASPPGS
Site 29S301LAPGSPASPPGSLEP
Site 30S305SPASPPGSLEPKAAR
Site 31S320LPPMRRESGRPIKPP
Site 32S334PRKDLPDSQQQHQSS
Site 33S340DSQQQHQSSKKGKLS
Site 34S341SQQQHQSSKKGKLSE
Site 35S347SSKKGKLSEQLKHCN
Site 36S362GILKELLSKKHAAYA
Site 37Y368LSKKHAAYAWPFYKP
Site 38Y373AAYAWPFYKPVDASA
Site 39Y386SALGLHDYHDIIKHP
Site 40S397IKHPMDLSTVKRKME
Site 41T398KHPMDLSTVKRKMEN
Site 42Y408RKMENRDYRDAQEFA
Site 43Y426RLMFSNCYKYNPPDH
Site 44Y450QDVFEFRYAKMPDEP
Site 45S476MPPGLAKSSSESSSE
Site 46S477PPGLAKSSSESSSEE
Site 47S478PGLAKSSSESSSEES
Site 48S480LAKSSSESSSEESSS
Site 49S481AKSSSESSSEESSSE
Site 50S482KSSSESSSEESSSES
Site 51S485SESSSEESSSESSSE
Site 52S486ESSSEESSSESSSEE
Site 53S487SSSEESSSESSSEEE
Site 54S489SEESSSESSSEEEEE
Site 55S490EESSSESSSEEEEEE
Site 56S491ESSSESSSEEEEEED
Site 57S507EDEEEEESESSDSEE
Site 58S509EEEEESESSDSEEER
Site 59S510EEEESESSDSEEERA
Site 60S512EESESSDSEEERAHR
Site 61S538HEQLAALSQGPISKP
Site 62S543ALSQGPISKPKRKRE
Site 63S587RPPQPKKSKKASGSG
Site 64S591PKKSKKASGSGGGSA
Site 65S593KSKKASGSGGGSAAL
Site 66S597ASGSGGGSAALGPSG
Site 67S603GSAALGPSGFGPSGG
Site 68S608GPSGFGPSGGSGTKL
Site 69S611GFGPSGGSGTKLPKK
Site 70T613GPSGGSGTKLPKKAT
Site 71T622LPKKATKTAPPALPT
Site 72S633ALPTGYDSEEEEESR
Site 73S639DSEEEEESRPMSYDE
Site 74S643EEESRPMSYDEKRQL
Site 75S651YDEKRQLSLDINKLP
Site 76S675IIQAREPSLRDSNPE
Site 77S679REPSLRDSNPEEIEI
Site 78T690EIEIDFETLKPSTLR
Site 79S694DFETLKPSTLRELER
Site 80T695FETLKPSTLRELERY
Site 81Y702TLRELERYVLSCLRK
Site 82S705ELERYVLSCLRKKPR
Site 83Y715RKKPRKPYTIKKPVG
Site 84T716KKPRKPYTIKKPVGK
Site 85T724IKKPVGKTKEELALE
Site 86S744EKRLQDVSGQLNSTK
Site 87S749DVSGQLNSTKKPPKK
Site 88T750VSGQLNSTKKPPKKA
Site 89T761PKKANEKTESSSAQQ
Site 90S763KANEKTESSSAQQVA
Site 91S772SAQQVAVSRLSASSS
Site 92S775QVAVSRLSASSSSSD
Site 93S777AVSRLSASSSSSDSS
Site 94S778VSRLSASSSSSDSSS
Site 95S779SRLSASSSSSDSSSS
Site 96S780RLSASSSSSDSSSSS
Site 97S781LSASSSSSDSSSSSS
Site 98S783ASSSSSDSSSSSSSS
Site 99S784SSSSSDSSSSSSSSS
Site 100S785SSSSDSSSSSSSSSS
Site 101S786SSSDSSSSSSSSSSS
Site 102S787SSDSSSSSSSSSSSD
Site 103S788SDSSSSSSSSSSSDT
Site 104S789DSSSSSSSSSSSDTS
Site 105S790SSSSSSSSSSSDTSD
Site 106S791SSSSSSSSSSDTSDS
Site 107S792SSSSSSSSSDTSDSD
Site 108S793SSSSSSSSDTSDSDS
Site 109T795SSSSSSDTSDSDSG_
Site 110S796SSSSSDTSDSDSG__
Site 111S798SSSDTSDSDSG____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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