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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADRA1D
Full Name:
Alpha-1D adrenergic receptor
Alias:
Alpha-1A adrenergic receptor;Alpha-1D adrenoreceptor;Alpha-adrenergic receptor 1a
Type:
Mass (Da):
60463
Number AA:
572
UniProt ID:
P25100
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
T
F
R
D
L
L
S
V
S
F
E
G
P
R
Site 2
S10
F
R
D
L
L
S
V
S
F
E
G
P
R
P
D
Site 3
S18
F
E
G
P
R
P
D
S
S
A
G
G
S
S
A
Site 4
S19
E
G
P
R
P
D
S
S
A
G
G
S
S
A
G
Site 5
S23
P
D
S
S
A
G
G
S
S
A
G
G
G
G
G
Site 6
S24
D
S
S
A
G
G
S
S
A
G
G
G
G
G
S
Site 7
S38
S
A
G
G
A
A
P
S
E
G
P
A
V
G
G
Site 8
S61
G
G
V
V
G
A
G
S
G
E
D
N
R
S
S
Site 9
S67
G
S
G
E
D
N
R
S
S
A
G
E
P
G
S
Site 10
S68
S
G
E
D
N
R
S
S
A
G
E
P
G
S
A
Site 11
S74
S
S
A
G
E
P
G
S
A
G
A
G
G
D
V
Site 12
S201
R
Y
V
G
V
R
H
S
L
K
Y
P
A
I
M
Site 13
Y204
G
V
R
H
S
L
K
Y
P
A
I
M
T
E
R
Site 14
T249
D
E
R
F
C
G
I
T
E
E
A
G
Y
A
V
Site 15
S283
R
V
Y
V
V
A
R
S
T
T
R
S
L
E
A
Site 16
S287
V
A
R
S
T
T
R
S
L
E
A
G
V
K
R
Site 17
S323
D
G
A
H
G
M
R
S
A
K
G
H
T
F
R
Site 18
T328
M
R
S
A
K
G
H
T
F
R
S
S
L
S
V
Site 19
S332
K
G
H
T
F
R
S
S
L
S
V
R
L
L
K
Site 20
S334
H
T
F
R
S
S
L
S
V
R
L
L
K
F
S
Site 21
S341
S
V
R
L
L
K
F
S
R
E
K
K
A
A
K
Site 22
Y402
S
C
V
N
P
L
I
Y
P
C
S
S
R
E
F
Site 23
S405
N
P
L
I
Y
P
C
S
S
R
E
F
K
R
A
Site 24
Y434
R
R
P
L
W
R
V
Y
G
H
H
W
R
A
S
Site 25
S441
Y
G
H
H
W
R
A
S
T
S
G
L
R
Q
D
Site 26
T442
G
H
H
W
R
A
S
T
S
G
L
R
Q
D
C
Site 27
S452
L
R
Q
D
C
A
P
S
S
G
D
A
P
P
G
Site 28
S453
R
Q
D
C
A
P
S
S
G
D
A
P
P
G
A
Site 29
T477
P
D
P
E
P
P
G
T
P
E
M
Q
A
P
V
Site 30
S486
E
M
Q
A
P
V
A
S
R
R
K
P
P
S
A
Site 31
S492
A
S
R
R
K
P
P
S
A
F
R
E
W
R
L
Site 32
T507
L
G
P
F
R
R
P
T
T
Q
L
R
A
K
V
Site 33
T508
G
P
F
R
R
P
T
T
Q
L
R
A
K
V
S
Site 34
S515
T
Q
L
R
A
K
V
S
S
L
S
H
K
I
R
Site 35
S516
Q
L
R
A
K
V
S
S
L
S
H
K
I
R
A
Site 36
S518
R
A
K
V
S
S
L
S
H
K
I
R
A
G
G
Site 37
S543
R
S
E
V
E
A
V
S
L
G
V
P
H
E
V
Site 38
Y559
E
G
A
T
C
Q
A
Y
E
L
A
D
Y
S
N
Site 39
Y564
Q
A
Y
E
L
A
D
Y
S
N
L
R
E
T
D
Site 40
S565
A
Y
E
L
A
D
Y
S
N
L
R
E
T
D
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation