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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IGFBP-5
Full Name:
Insulin-like growth factor-binding protein 5
Alias:
IBP- 5; IBP5; IGF-binding protein 5; IGFBP5; insulin-like growth factor binding protein 5; Insulin-like growth factor-binding protein 5 precursor
Type:
Mass (Da):
30570
Number AA:
272
UniProt ID:
P24593
International Prot ID:
IPI00029236
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016942
Uniprot
OncoNet
Molecular Function:
GO:0031994
PhosphoSite+
KinaseNET
Biological Process:
GO:0043569
GO:0014912
GO:0048662
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
G
P
A
Q
S
L
G
S
F
V
H
C
E
P
C
Site 2
S36
P
C
D
E
K
A
L
S
M
C
P
P
S
P
L
Site 3
Y70
E
G
Q
S
C
G
V
Y
T
E
R
C
A
Q
G
Site 4
T71
G
Q
S
C
G
V
Y
T
E
R
C
A
Q
G
L
Site 5
S105
G
V
C
L
N
E
K
S
Y
R
E
Q
V
K
I
Site 6
S116
Q
V
K
I
E
R
D
S
R
E
H
E
E
P
T
Site 7
T124
R
E
H
E
E
P
T
T
S
E
M
A
E
E
T
Site 8
S125
E
H
E
E
P
T
T
S
E
M
A
E
E
T
Y
Site 9
T131
T
S
E
M
A
E
E
T
Y
S
P
K
I
F
R
Site 10
S133
E
M
A
E
E
T
Y
S
P
K
I
F
R
P
K
Site 11
S145
R
P
K
H
T
R
I
S
E
L
K
A
E
A
V
Site 12
T161
K
D
R
R
K
K
L
T
Q
S
K
F
V
G
G
Site 13
S163
R
R
K
K
L
T
Q
S
K
F
V
G
G
A
E
Site 14
S179
T
A
H
P
R
I
I
S
A
P
E
M
R
Q
E
Site 15
S187
A
P
E
M
R
Q
E
S
E
Q
G
P
C
R
R
Site 16
S199
C
R
R
H
M
E
A
S
L
Q
E
L
K
A
S
Site 17
S206
S
L
Q
E
L
K
A
S
P
R
M
V
P
R
A
Site 18
Y215
R
M
V
P
R
A
V
Y
L
P
N
C
D
R
K
Site 19
Y225
N
C
D
R
K
G
F
Y
K
R
K
Q
C
K
P
Site 20
S233
K
R
K
Q
C
K
P
S
R
G
R
K
R
G
I
Site 21
Y256
M
K
L
P
G
M
E
Y
V
D
G
D
F
Q
C
Site 22
T265
D
G
D
F
Q
C
H
T
F
D
S
S
N
V
E
Site 23
S268
F
Q
C
H
T
F
D
S
S
N
V
E
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation