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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Mmp11
Full Name:
Stromelysin-3
Alias:
EC 3.4.24.-; Matrix metallopeptidase 11 (stromelysin 3); Matrix metalloproteinase 11; Sl-3; St3; Stmy3
Type:
Protease
Mass (Da):
54618
Number AA:
488
UniProt ID:
P24347
International Prot ID:
IPI00306778
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0004222
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0030574
GO:0007275
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S58
W
H
A
A
L
P
S
S
P
A
P
A
P
A
T
Site 2
S73
Q
E
A
P
R
P
A
S
S
L
R
P
P
R
C
Site 3
S74
E
A
P
R
P
A
S
S
L
R
P
P
R
C
G
Site 4
S86
R
C
G
V
P
D
P
S
D
G
L
S
A
R
N
Site 5
S90
P
D
P
S
D
G
L
S
A
R
N
R
Q
K
R
Site 6
S101
R
Q
K
R
F
V
L
S
G
G
R
W
E
K
T
Site 7
T108
S
G
G
R
W
E
K
T
D
L
T
Y
R
I
L
Site 8
T111
R
W
E
K
T
D
L
T
Y
R
I
L
R
F
P
Site 9
Y112
W
E
K
T
D
L
T
Y
R
I
L
R
F
P
W
Site 10
T129
V
Q
E
Q
V
R
Q
T
M
A
E
A
L
K
V
Site 11
T144
W
S
D
V
T
P
L
T
F
T
E
V
H
E
G
Site 12
Y162
I
M
I
D
F
A
R
Y
W
H
G
D
D
L
P
Site 13
T185
A
H
A
F
F
P
K
T
H
R
E
G
D
V
H
Site 14
Y195
E
G
D
V
H
F
D
Y
D
E
T
W
T
I
G
Site 15
Y241
S
A
F
Y
T
F
R
Y
P
L
S
L
S
P
D
Site 16
S244
Y
T
F
R
Y
P
L
S
L
S
P
D
D
C
R
Site 17
S246
F
R
Y
P
L
S
L
S
P
D
D
C
R
G
V
Site 18
Y257
C
R
G
V
Q
H
L
Y
G
Q
P
W
P
T
V
Site 19
T263
L
Y
G
Q
P
W
P
T
V
T
S
R
T
P
A
Site 20
T268
W
P
T
V
T
S
R
T
P
A
L
G
P
Q
A
Site 21
T279
G
P
Q
A
G
I
D
T
N
E
I
A
P
L
E
Site 22
Y328
G
G
Q
L
Q
P
G
Y
P
A
L
A
S
R
H
Site 23
S333
P
G
Y
P
A
L
A
S
R
H
W
Q
G
L
P
Site 24
S341
R
H
W
Q
G
L
P
S
P
V
D
A
A
F
E
Site 25
Y365
Q
G
A
Q
Y
W
V
Y
D
G
E
K
P
V
L
Site 26
Y401
G
P
E
K
N
K
I
Y
F
F
R
G
R
D
Y
Site 27
Y408
Y
F
F
R
G
R
D
Y
W
R
F
H
P
S
T
Site 28
S414
D
Y
W
R
F
H
P
S
T
R
R
V
D
S
P
Site 29
T415
Y
W
R
F
H
P
S
T
R
R
V
D
S
P
V
Site 30
S420
P
S
T
R
R
V
D
S
P
V
P
R
R
A
T
Site 31
T427
S
P
V
P
R
R
A
T
D
W
R
G
V
P
S
Site 32
Y446
A
F
Q
D
A
D
G
Y
A
Y
F
L
R
G
R
Site 33
Y448
Q
D
A
D
G
Y
A
Y
F
L
R
G
R
L
Y
Site 34
Y455
Y
F
L
R
G
R
L
Y
W
K
F
D
P
V
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation