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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAX3
Full Name:
Paired box protein Pax-3
Alias:
CDHS; HUP2; Paired box gene 3; Paired box Pax-3; WS1
Type:
Transcription protein
Mass (Da):
52968
Number AA:
479
UniProt ID:
P23760
International Prot ID:
IPI00012896
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0009887
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
T
L
A
G
A
V
P
Site 2
T3
_
_
_
_
_
M
T
T
L
A
G
A
V
P
R
Site 3
Y20
R
P
G
P
G
Q
N
Y
P
R
S
G
F
P
L
Site 4
S23
P
G
Q
N
Y
P
R
S
G
F
P
L
E
V
S
Site 5
S30
S
G
F
P
L
E
V
S
T
P
L
G
Q
G
R
Site 6
S73
G
I
R
P
C
V
I
S
R
Q
L
R
V
S
H
Site 7
S79
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
I
Site 8
Y90
V
S
K
I
L
C
R
Y
Q
E
T
G
S
I
R
Site 9
S95
C
R
Y
Q
E
T
G
S
I
R
P
G
A
I
G
Site 10
T111
S
K
P
K
Q
V
T
T
P
D
V
E
K
K
I
Site 11
Y121
V
E
K
K
I
E
E
Y
K
R
E
N
P
G
M
Site 12
T147
D
A
V
C
D
R
N
T
V
P
S
V
S
S
I
Site 13
S150
C
D
R
N
T
V
P
S
V
S
S
I
S
R
I
Site 14
S152
R
N
T
V
P
S
V
S
S
I
S
R
I
L
R
Site 15
S153
N
T
V
P
S
V
S
S
I
S
R
I
L
R
S
Site 16
S160
S
I
S
R
I
L
R
S
K
F
G
K
G
E
E
Site 17
S180
E
R
K
E
A
E
E
S
E
K
K
A
K
H
S
Site 18
S187
S
E
K
K
A
K
H
S
I
D
G
I
L
S
E
Site 19
S193
H
S
I
D
G
I
L
S
E
R
A
S
A
P
Q
Site 20
S197
G
I
L
S
E
R
A
S
A
P
Q
S
D
E
G
Site 21
S201
E
R
A
S
A
P
Q
S
D
E
G
S
D
I
D
Site 22
S205
A
P
Q
S
D
E
G
S
D
I
D
S
E
P
D
Site 23
S209
D
E
G
S
D
I
D
S
E
P
D
L
P
L
K
Site 24
S222
L
K
R
K
Q
R
R
S
R
T
T
F
T
A
E
Site 25
T224
R
K
Q
R
R
S
R
T
T
F
T
A
E
Q
L
Site 26
T225
K
Q
R
R
S
R
T
T
F
T
A
E
Q
L
E
Site 27
T241
L
E
R
A
F
E
R
T
H
Y
P
D
I
Y
T
Site 28
Y243
R
A
F
E
R
T
H
Y
P
D
I
Y
T
R
E
Site 29
Y247
R
T
H
Y
P
D
I
Y
T
R
E
E
L
A
Q
Site 30
Y305
A
M
P
T
L
P
T
Y
Q
L
S
E
T
S
Y
Site 31
S308
T
L
P
T
Y
Q
L
S
E
T
S
Y
Q
P
T
Site 32
S311
T
Y
Q
L
S
E
T
S
Y
Q
P
T
S
I
P
Site 33
Y312
Y
Q
L
S
E
T
S
Y
Q
P
T
S
I
P
Q
Site 34
T315
S
E
T
S
Y
Q
P
T
S
I
P
Q
A
V
S
Site 35
S316
E
T
S
Y
Q
P
T
S
I
P
Q
A
V
S
D
Site 36
S322
T
S
I
P
Q
A
V
S
D
P
S
S
T
V
H
Site 37
S326
Q
A
V
S
D
P
S
S
T
V
H
R
P
Q
P
Site 38
T327
A
V
S
D
P
S
S
T
V
H
R
P
Q
P
L
Site 39
S337
R
P
Q
P
L
P
P
S
T
V
H
Q
S
T
I
Site 40
T338
P
Q
P
L
P
P
S
T
V
H
Q
S
T
I
P
Site 41
S342
P
P
S
T
V
H
Q
S
T
I
P
S
N
P
D
Site 42
T343
P
S
T
V
H
Q
S
T
I
P
S
N
P
D
S
Site 43
S346
V
H
Q
S
T
I
P
S
N
P
D
S
S
S
A
Site 44
S350
T
I
P
S
N
P
D
S
S
S
A
Y
C
L
P
Site 45
S351
I
P
S
N
P
D
S
S
S
A
Y
C
L
P
S
Site 46
S352
P
S
N
P
D
S
S
S
A
Y
C
L
P
S
T
Site 47
Y354
N
P
D
S
S
S
A
Y
C
L
P
S
T
R
H
Site 48
S358
S
S
A
Y
C
L
P
S
T
R
H
G
F
S
S
Site 49
T359
S
A
Y
C
L
P
S
T
R
H
G
F
S
S
Y
Site 50
S364
P
S
T
R
H
G
F
S
S
Y
T
D
S
F
V
Site 51
S365
S
T
R
H
G
F
S
S
Y
T
D
S
F
V
P
Site 52
Y366
T
R
H
G
F
S
S
Y
T
D
S
F
V
P
P
Site 53
T367
R
H
G
F
S
S
Y
T
D
S
F
V
P
P
S
Site 54
S369
G
F
S
S
Y
T
D
S
F
V
P
P
S
G
P
Site 55
S374
T
D
S
F
V
P
P
S
G
P
S
N
P
M
N
Site 56
S377
F
V
P
P
S
G
P
S
N
P
M
N
P
T
I
Site 57
T383
P
S
N
P
M
N
P
T
I
G
N
G
L
S
P
Site 58
T397
P
Q
V
M
G
L
L
T
N
H
G
G
V
P
H
Site 59
T408
G
V
P
H
Q
P
Q
T
D
Y
A
L
S
P
L
Site 60
Y410
P
H
Q
P
Q
T
D
Y
A
L
S
P
L
T
G
Site 61
S413
P
Q
T
D
Y
A
L
S
P
L
T
G
G
L
E
Site 62
T423
T
G
G
L
E
P
T
T
T
V
S
A
S
C
S
Site 63
T424
G
G
L
E
P
T
T
T
V
S
A
S
C
S
Q
Site 64
S426
L
E
P
T
T
T
V
S
A
S
C
S
Q
R
L
Site 65
S428
P
T
T
T
V
S
A
S
C
S
Q
R
L
D
H
Site 66
S430
T
T
V
S
A
S
C
S
Q
R
L
D
H
M
K
Site 67
S438
Q
R
L
D
H
M
K
S
L
D
S
L
P
T
S
Site 68
S441
D
H
M
K
S
L
D
S
L
P
T
S
Q
S
Y
Site 69
S445
S
L
D
S
L
P
T
S
Q
S
Y
C
P
P
T
Site 70
S447
D
S
L
P
T
S
Q
S
Y
C
P
P
T
Y
S
Site 71
Y448
S
L
P
T
S
Q
S
Y
C
P
P
T
Y
S
T
Site 72
T452
S
Q
S
Y
C
P
P
T
Y
S
T
T
G
Y
S
Site 73
Y453
Q
S
Y
C
P
P
T
Y
S
T
T
G
Y
S
M
Site 74
S454
S
Y
C
P
P
T
Y
S
T
T
G
Y
S
M
D
Site 75
Y458
P
T
Y
S
T
T
G
Y
S
M
D
P
V
T
G
Site 76
S459
T
Y
S
T
T
G
Y
S
M
D
P
V
T
G
Y
Site 77
T464
G
Y
S
M
D
P
V
T
G
Y
Q
Y
G
Q
Y
Site 78
Y466
S
M
D
P
V
T
G
Y
Q
Y
G
Q
Y
G
Q
Site 79
Y468
D
P
V
T
G
Y
Q
Y
G
Q
Y
G
Q
S
K
Site 80
Y471
T
G
Y
Q
Y
G
Q
Y
G
Q
S
K
P
W
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation