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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BDNF
Full Name:
Brain-derived neurotrophic factor
Alias:
Abrineurin
Type:
Vesicle protein; Membrane bound, extracellular region, cytoplasm
Mass (Da):
27818
Number AA:
247
UniProt ID:
P23560
International Prot ID:
IPI00012058
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0008083
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Brain-derived neurotrophic factor pan-specific antibody AB-NN216-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN216-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
R
G
Q
G
G
L
A
Y
P
G
V
R
T
H
G
Site 2
T42
P
G
V
R
T
H
G
T
L
E
S
V
N
G
P
Site 3
S45
R
T
H
G
T
L
E
S
V
N
G
P
K
A
G
Site 4
T57
K
A
G
S
R
G
L
T
S
L
A
D
T
F
E
Site 5
S58
A
G
S
R
G
L
T
S
L
A
D
T
F
E
H
Site 6
T62
G
L
T
S
L
A
D
T
F
E
H
V
I
E
E
Site 7
Y90
N
N
K
D
A
D
L
Y
T
S
R
V
M
L
S
Site 8
T91
N
K
D
A
D
L
Y
T
S
R
V
M
L
S
S
Site 9
S92
K
D
A
D
L
Y
T
S
R
V
M
L
S
S
Q
Site 10
S97
Y
T
S
R
V
M
L
S
S
Q
V
P
L
E
P
Site 11
S98
T
S
R
V
M
L
S
S
Q
V
P
L
E
P
P
Site 12
Y116
L
L
E
E
Y
K
N
Y
L
D
A
A
N
M
S
Site 13
S123
Y
L
D
A
A
N
M
S
M
R
V
R
R
H
S
Site 14
S130
S
M
R
V
R
R
H
S
D
P
A
R
R
G
E
Site 15
S139
P
A
R
R
G
E
L
S
V
C
D
S
I
S
E
Site 16
T149
D
S
I
S
E
W
V
T
A
A
D
K
K
T
A
Site 17
T155
V
T
A
A
D
K
K
T
A
V
D
M
S
G
G
Site 18
S173
V
L
E
K
V
P
V
S
K
G
Q
L
K
Q
Y
Site 19
Y180
S
K
G
Q
L
K
Q
Y
F
Y
E
T
K
C
N
Site 20
Y182
G
Q
L
K
Q
Y
F
Y
E
T
K
C
N
P
M
Site 21
Y191
T
K
C
N
P
M
G
Y
T
K
E
G
C
R
G
Site 22
T211
W
N
S
Q
C
R
T
T
Q
S
Y
V
R
A
L
Site 23
S213
S
Q
C
R
T
T
Q
S
Y
V
R
A
L
T
M
Site 24
Y214
Q
C
R
T
T
Q
S
Y
V
R
A
L
T
M
D
Site 25
T219
Q
S
Y
V
R
A
L
T
M
D
S
K
K
R
I
Site 26
S222
V
R
A
L
T
M
D
S
K
K
R
I
G
W
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation