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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBLN1
Full Name:
Fibulin-1
Alias:
FBLN; fibulin 1; Fibulin-1
Type:
Extracellular matrix
Mass (Da):
77261
Number AA:
703
UniProt ID:
P23142
International Prot ID:
IPI00333852
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0005578
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005201
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0044419
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
R
A
A
P
S
R
R
V
P
L
P
L
Site 2
T45
A
D
G
H
R
M
A
T
H
Q
K
D
C
S
L
Site 3
S51
A
T
H
Q
K
D
C
S
L
P
Y
A
T
E
S
Site 4
T56
D
C
S
L
P
Y
A
T
E
S
K
E
C
R
M
Site 5
T93
N
E
Q
D
R
C
A
T
P
H
G
D
N
A
S
Site 6
S100
T
P
H
G
D
N
A
S
L
E
A
T
F
V
K
Site 7
T104
D
N
A
S
L
E
A
T
F
V
K
R
C
C
H
Site 8
S125
A
A
Q
A
Q
G
Q
S
C
E
Y
S
L
M
V
Site 9
Y128
A
Q
G
Q
S
C
E
Y
S
L
M
V
G
Y
Q
Site 10
Y134
E
Y
S
L
M
V
G
Y
Q
C
G
Q
V
F
Q
Site 11
S147
F
Q
A
C
C
V
K
S
Q
E
T
G
D
L
D
Site 12
Y175
E
E
E
Q
E
D
P
Y
L
N
D
R
C
R
G
Site 13
T193
C
K
Q
Q
C
R
D
T
G
D
E
V
V
C
S
Site 14
S213
Q
L
L
S
D
G
V
S
C
E
D
V
N
E
C
Site 15
T222
E
D
V
N
E
C
I
T
G
S
H
S
C
R
L
Site 16
S224
V
N
E
C
I
T
G
S
H
S
C
R
L
G
E
Site 17
S226
E
C
I
T
G
S
H
S
C
R
L
G
E
S
C
Site 18
S232
H
S
C
R
L
G
E
S
C
I
N
T
V
G
S
Site 19
S239
S
C
I
N
T
V
G
S
F
R
C
Q
R
D
S
Site 20
S246
S
F
R
C
Q
R
D
S
S
C
G
T
G
Y
E
Site 21
S247
F
R
C
Q
R
D
S
S
C
G
T
G
Y
E
L
Site 22
T250
Q
R
D
S
S
C
G
T
G
Y
E
L
T
E
D
Site 23
Y252
D
S
S
C
G
T
G
Y
E
L
T
E
D
N
S
Site 24
T255
C
G
T
G
Y
E
L
T
E
D
N
S
C
K
D
Site 25
S285
I
C
Q
N
T
L
G
S
F
R
C
R
P
K
L
Site 26
S296
R
P
K
L
Q
C
K
S
G
F
I
Q
D
A
L
Site 27
T333
I
N
T
E
G
S
Y
T
C
Q
K
N
V
P
N
Site 28
Y345
V
P
N
C
G
R
G
Y
H
L
N
E
E
G
T
Site 29
S376
K
G
H
R
C
V
N
S
P
G
S
F
R
C
E
Site 30
S379
R
C
V
N
S
P
G
S
F
R
C
E
C
K
T
Site 31
Y388
R
C
E
C
K
T
G
Y
Y
F
D
G
I
S
R
Site 32
Y389
C
E
C
K
T
G
Y
Y
F
D
G
I
S
R
M
Site 33
Y406
D
V
N
E
C
Q
R
Y
P
G
R
L
C
G
H
Site 34
T418
C
G
H
K
C
E
N
T
L
G
S
Y
L
C
S
Site 35
S433
C
S
V
G
F
R
L
S
V
D
G
R
S
C
E
Site 36
S438
R
L
S
V
D
G
R
S
C
E
D
I
N
E
C
Site 37
S446
C
E
D
I
N
E
C
S
S
S
P
C
S
Q
E
Site 38
S447
E
D
I
N
E
C
S
S
S
P
C
S
Q
E
C
Site 39
S448
D
I
N
E
C
S
S
S
P
C
S
Q
E
C
A
Site 40
S451
E
C
S
S
S
P
C
S
Q
E
C
A
N
V
Y
Site 41
Y458
S
Q
E
C
A
N
V
Y
G
S
Y
Q
C
Y
C
Site 42
Y464
V
Y
G
S
Y
Q
C
Y
C
R
R
G
Y
Q
L
Site 43
Y469
Q
C
Y
C
R
R
G
Y
Q
L
S
D
V
D
G
Site 44
S472
C
R
R
G
Y
Q
L
S
D
V
D
G
V
T
C
Site 45
T478
L
S
D
V
D
G
V
T
C
E
D
I
D
E
C
Site 46
S508
I
P
G
S
F
Q
C
S
C
P
S
S
G
Y
R
Site 47
S511
S
F
Q
C
S
C
P
S
S
G
Y
R
L
A
P
Site 48
S512
F
Q
C
S
C
P
S
S
G
Y
R
L
A
P
N
Site 49
S563
C
P
E
N
Y
R
R
S
A
A
T
L
Q
Q
E
Site 50
T566
N
Y
R
R
S
A
A
T
L
Q
Q
E
K
T
D
Site 51
T572
A
T
L
Q
Q
E
K
T
D
T
V
R
C
I
K
Site 52
T574
L
Q
Q
E
K
T
D
T
V
R
C
I
K
S
C
Site 53
T605
H
T
V
I
S
L
P
T
F
R
E
F
T
R
P
Site 54
T610
L
P
T
F
R
E
F
T
R
P
E
E
I
I
F
Site 55
S628
I
T
P
P
H
P
A
S
Q
A
N
I
I
F
D
Site 56
T637
A
N
I
I
F
D
I
T
E
G
N
L
R
D
S
Site 57
S644
T
E
G
N
L
R
D
S
F
D
I
I
K
R
Y
Site 58
Y651
S
F
D
I
I
K
R
Y
M
D
G
M
T
V
G
Site 59
T656
K
R
Y
M
D
G
M
T
V
G
V
V
R
Q
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation