KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LHR
Full Name:
Lutropin-choriogonadotropic hormone receptor
Alias:
LCGR; LGR2; LH/CG-R; LHCGR; LHRHR; LSHR; LSH-R; Luteinizing hormone receptor; Luteinizing hormone/choriogonadotropin receptor; Lutropin-choriogonadotropic hormone receptor
Type:
Receptor, G protein-coupled
Mass (Da):
78616
Number AA:
699
UniProt ID:
P22888
International Prot ID:
IPI00299615
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005768
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004964
PhosphoSite+
KinaseNET
Biological Process:
GO:0030539
GO:0008584
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S81
E
V
I
K
I
E
I
S
Q
I
D
S
L
E
R
Site 2
S85
I
E
I
S
Q
I
D
S
L
E
R
I
E
A
N
Site 3
Y113
Q
N
T
K
N
L
R
Y
I
E
P
G
A
F
I
Site 4
T133
K
Y
L
S
I
C
N
T
G
I
R
K
F
P
D
Site 5
T142
I
R
K
F
P
D
V
T
K
V
F
S
S
E
S
Site 6
S176
F
Q
G
M
N
N
E
S
V
T
L
K
L
Y
G
Site 7
Y182
E
S
V
T
L
K
L
Y
G
N
G
F
E
E
V
Site 8
S191
N
G
F
E
E
V
Q
S
H
A
F
N
G
T
T
Site 9
T222
N
G
A
F
R
G
A
T
G
P
K
T
L
D
I
Site 10
T226
R
G
A
T
G
P
K
T
L
D
I
S
S
T
K
Site 11
S231
P
K
T
L
D
I
S
S
T
K
L
Q
A
L
P
Site 12
S239
T
K
L
Q
A
L
P
S
Y
G
L
E
S
I
Q
Site 13
Y240
K
L
Q
A
L
P
S
Y
G
L
E
S
I
Q
R
Site 14
T251
S
I
Q
R
L
I
A
T
S
S
Y
S
L
K
K
Site 15
S252
I
Q
R
L
I
A
T
S
S
Y
S
L
K
K
L
Site 16
S253
Q
R
L
I
A
T
S
S
Y
S
L
K
K
L
P
Site 17
S255
L
I
A
T
S
S
Y
S
L
K
K
L
P
S
R
Site 18
S261
Y
S
L
K
K
L
P
S
R
E
T
F
V
N
L
Site 19
T264
K
K
L
P
S
R
E
T
F
V
N
L
L
E
A
Site 20
S293
P
T
K
E
Q
N
F
S
H
S
I
S
E
N
F
Site 21
S295
K
E
Q
N
F
S
H
S
I
S
E
N
F
S
K
Site 22
S297
Q
N
F
S
H
S
I
S
E
N
F
S
K
Q
C
Site 23
S301
H
S
I
S
E
N
F
S
K
Q
C
E
S
T
V
Site 24
S306
N
F
S
K
Q
C
E
S
T
V
R
K
V
S
N
Site 25
T307
F
S
K
Q
C
E
S
T
V
R
K
V
S
N
K
Site 26
S312
E
S
T
V
R
K
V
S
N
K
T
L
Y
S
S
Site 27
T315
V
R
K
V
S
N
K
T
L
Y
S
S
M
L
A
Site 28
Y317
K
V
S
N
K
T
L
Y
S
S
M
L
A
E
S
Site 29
S319
S
N
K
T
L
Y
S
S
M
L
A
E
S
E
L
Site 30
S324
Y
S
S
M
L
A
E
S
E
L
S
G
W
D
Y
Site 31
S327
M
L
A
E
S
E
L
S
G
W
D
Y
E
Y
G
Site 32
Y331
S
E
L
S
G
W
D
Y
E
Y
G
F
C
L
P
Site 33
Y333
L
S
G
W
D
Y
E
Y
G
F
C
L
P
K
T
Site 34
T340
Y
G
F
C
L
P
K
T
P
R
C
A
P
E
P
Site 35
S420
L
L
I
A
S
V
D
S
Q
T
K
G
Q
Y
Y
Site 36
Y427
S
Q
T
K
G
Q
Y
Y
N
H
A
I
D
W
Q
Site 37
T435
N
H
A
I
D
W
Q
T
G
S
G
C
S
T
A
Site 38
S437
A
I
D
W
Q
T
G
S
G
C
S
T
A
G
F
Site 39
T467
I
T
L
E
R
W
H
T
I
T
Y
A
I
H
L
Site 40
T469
L
E
R
W
H
T
I
T
Y
A
I
H
L
D
Q
Site 41
Y550
C
A
C
Y
I
K
I
Y
F
A
V
R
N
P
E
Site 42
T561
R
N
P
E
L
M
A
T
N
K
D
T
K
I
A
Site 43
Y651
C
K
R
R
A
E
L
Y
R
R
K
D
F
S
A
Site 44
S657
L
Y
R
R
K
D
F
S
A
Y
T
S
N
C
K
Site 45
Y659
R
R
K
D
F
S
A
Y
T
S
N
C
K
N
G
Site 46
S661
K
D
F
S
A
Y
T
S
N
C
K
N
G
F
T
Site 47
T668
S
N
C
K
N
G
F
T
G
S
N
K
P
S
Q
Site 48
S670
C
K
N
G
F
T
G
S
N
K
P
S
Q
S
T
Site 49
S674
F
T
G
S
N
K
P
S
Q
S
T
L
K
L
S
Site 50
S676
G
S
N
K
P
S
Q
S
T
L
K
L
S
T
L
Site 51
T677
S
N
K
P
S
Q
S
T
L
K
L
S
T
L
H
Site 52
S681
S
Q
S
T
L
K
L
S
T
L
H
C
Q
G
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation