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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UQCRC2
Full Name:
Cytochrome b-c1 complex subunit 2, mitochondrial
Alias:
Complex III subunit II; EC 1.10.2.2; QCR2; Ubiquinol-cytochrome c reductase core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial; UQCR2
Type:
Enzyme - Oxidoreductase, Energy Metabolism group, Oxidative phosphorylation family
Mass (Da):
48443
Number AA:
453
UniProt ID:
P22695
International Prot ID:
IPI00305383
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0070469
Uniprot
OncoNet
Molecular Function:
GO:0004222
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0009060
GO:0022900
GO:0006119
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
K
L
L
T
R
A
G
S
F
S
R
F
Y
S
L
Site 2
S11
L
T
R
A
G
S
F
S
R
F
Y
S
L
K
V
Site 3
Y14
A
G
S
F
S
R
F
Y
S
L
K
V
A
P
K
Site 4
S15
G
S
F
S
R
F
Y
S
L
K
V
A
P
K
V
Site 5
Y55
V
I
A
S
L
E
N
Y
S
P
V
S
R
I
G
Site 6
Y71
F
I
K
A
G
S
R
Y
E
D
F
S
N
L
G
Site 7
S75
G
S
R
Y
E
D
F
S
N
L
G
T
T
H
L
Site 8
T79
E
D
F
S
N
L
G
T
T
H
L
L
R
L
T
Site 9
T86
T
T
H
L
L
R
L
T
S
S
L
T
T
K
G
Site 10
S87
T
H
L
L
R
L
T
S
S
L
T
T
K
G
A
Site 11
S88
H
L
L
R
L
T
S
S
L
T
T
K
G
A
S
Site 12
T90
L
R
L
T
S
S
L
T
T
K
G
A
S
S
F
Site 13
T91
R
L
T
S
S
L
T
T
K
G
A
S
S
F
K
Site 14
S96
L
T
T
K
G
A
S
S
F
K
I
T
R
G
I
Site 15
T100
G
A
S
S
F
K
I
T
R
G
I
E
A
V
G
Site 16
S111
E
A
V
G
G
K
L
S
V
T
A
T
R
E
N
Site 17
T113
V
G
G
K
L
S
V
T
A
T
R
E
N
M
A
Site 18
T115
G
K
L
S
V
T
A
T
R
E
N
M
A
Y
T
Site 19
Y121
A
T
R
E
N
M
A
Y
T
V
E
C
L
R
G
Site 20
T122
T
R
E
N
M
A
Y
T
V
E
C
L
R
G
D
Site 21
T171
V
A
F
Q
N
P
Q
T
H
V
I
E
N
L
H
Site 22
Y191
N
A
L
A
N
P
L
Y
C
P
D
Y
R
I
G
Site 23
Y195
N
P
L
Y
C
P
D
Y
R
I
G
K
V
T
S
Site 24
T201
D
Y
R
I
G
K
V
T
S
E
E
L
H
Y
F
Site 25
S202
Y
R
I
G
K
V
T
S
E
E
L
H
Y
F
V
Site 26
Y207
V
T
S
E
E
L
H
Y
F
V
Q
N
H
F
T
Site 27
S226
A
L
I
G
L
G
V
S
H
P
V
L
K
Q
V
Site 28
S247
M
R
G
G
L
G
L
S
G
A
K
A
N
Y
R
Site 29
S303
G
P
H
V
K
R
G
S
N
T
T
S
H
L
H
Site 30
S307
K
R
G
S
N
T
T
S
H
L
H
Q
A
V
A
Site 31
S324
T
Q
Q
P
F
D
V
S
A
F
N
A
S
Y
S
Site 32
S329
D
V
S
A
F
N
A
S
Y
S
D
S
G
L
F
Site 33
S333
F
N
A
S
Y
S
D
S
G
L
F
G
I
Y
T
Site 34
S367
T
I
A
Q
G
N
L
S
N
T
D
V
Q
A
A
Site 35
Y382
K
N
K
L
K
A
G
Y
L
M
S
V
E
S
S
Site 36
S388
G
Y
L
M
S
V
E
S
S
E
C
F
L
E
E
Site 37
S410
A
G
S
Y
M
P
P
S
T
V
L
Q
Q
I
D
Site 38
T411
G
S
Y
M
P
P
S
T
V
L
Q
Q
I
D
S
Site 39
S433
N
A
A
K
K
F
V
S
G
Q
K
S
M
A
A
Site 40
S437
K
F
V
S
G
Q
K
S
M
A
A
S
G
N
L
Site 41
S441
G
Q
K
S
M
A
A
S
G
N
L
G
H
T
P
Site 42
T447
A
S
G
N
L
G
H
T
P
F
V
D
E
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation