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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LPO
Full Name:
Lactoperoxidase
Alias:
Lactoperoxidase; PERL; Salivary peroxidase; SAPX; SPO
Type:
EC 1.11.1.7; Oxidoreductase
Mass (Da):
80269
Number AA:
712
UniProt ID:
P22079
International Prot ID:
IPI00025023
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0020037
GO:0004601
PhosphoSite+
KinaseNET
Biological Process:
GO:0042744
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
H
L
P
A
L
L
A
S
L
I
L
L
Q
A
A
Site 2
T28
A
S
T
T
R
A
Q
T
T
R
T
S
A
I
S
Site 3
S32
R
A
Q
T
T
R
T
S
A
I
S
D
T
V
S
Site 4
S35
T
T
R
T
S
A
I
S
D
T
V
S
Q
A
K
Site 5
T37
R
T
S
A
I
S
D
T
V
S
Q
A
K
V
Q
Site 6
S39
S
A
I
S
D
T
V
S
Q
A
K
V
Q
V
N
Site 7
T58
D
S
R
T
R
L
K
T
A
M
S
S
E
T
P
Site 8
S61
T
R
L
K
T
A
M
S
S
E
T
P
T
S
R
Site 9
S62
R
L
K
T
A
M
S
S
E
T
P
T
S
R
Q
Site 10
T64
K
T
A
M
S
S
E
T
P
T
S
R
Q
L
S
Site 11
T66
A
M
S
S
E
T
P
T
S
R
Q
L
S
E
Y
Site 12
S67
M
S
S
E
T
P
T
S
R
Q
L
S
E
Y
L
Site 13
S71
T
P
T
S
R
Q
L
S
E
Y
L
K
H
A
K
Site 14
Y73
T
S
R
Q
L
S
E
Y
L
K
H
A
K
G
R
Site 15
T83
H
A
K
G
R
T
R
T
A
I
R
N
G
Q
V
Site 16
S94
N
G
Q
V
W
E
E
S
L
K
R
L
R
Q
K
Site 17
S103
K
R
L
R
Q
K
A
S
L
T
N
V
T
D
P
Site 18
T105
L
R
Q
K
A
S
L
T
N
V
T
D
P
S
L
Site 19
S111
L
T
N
V
T
D
P
S
L
D
L
T
S
L
S
Site 20
S136
V
V
R
C
D
P
C
S
P
Y
R
T
I
T
G
Site 21
Y138
R
C
D
P
C
S
P
Y
R
T
I
T
G
D
C
Site 22
T142
C
S
P
Y
R
T
I
T
G
D
C
N
N
R
R
Site 23
S173
A
E
Y
E
D
G
L
S
L
P
F
G
W
T
P
Site 24
T179
L
S
L
P
F
G
W
T
P
G
K
T
R
N
G
Site 25
T183
F
G
W
T
P
G
K
T
R
N
G
F
P
L
P
Site 26
S214
G
V
L
D
Q
N
R
S
L
L
F
M
Q
W
G
Site 27
T234
D
L
D
F
A
P
D
T
E
L
G
S
S
E
Y
Site 28
S238
A
P
D
T
E
L
G
S
S
E
Y
S
K
A
Q
Site 29
S239
P
D
T
E
L
G
S
S
E
Y
S
K
A
Q
C
Site 30
S242
E
L
G
S
S
E
Y
S
K
A
Q
C
D
E
Y
Site 31
Y249
S
K
A
Q
C
D
E
Y
C
I
Q
G
D
N
C
Site 32
T286
R
A
G
F
V
C
P
T
P
P
Y
K
S
L
A
Site 33
Y289
F
V
C
P
T
P
P
Y
K
S
L
A
R
E
Q
Site 34
S291
C
P
T
P
P
Y
K
S
L
A
R
E
Q
I
N
Site 35
S311
L
D
A
S
F
V
Y
S
S
E
P
S
L
A
S
Site 36
S312
D
A
S
F
V
Y
S
S
E
P
S
L
A
S
R
Site 37
S315
F
V
Y
S
S
E
P
S
L
A
S
R
L
R
N
Site 38
S318
S
S
E
P
S
L
A
S
R
L
R
N
L
S
S
Site 39
S337
M
A
V
N
Q
E
V
S
D
H
G
L
P
Y
L
Site 40
Y343
V
S
D
H
G
L
P
Y
L
P
Y
D
S
K
K
Site 41
Y346
H
G
L
P
Y
L
P
Y
D
S
K
K
P
S
P
Site 42
S348
L
P
Y
L
P
Y
D
S
K
K
P
S
P
C
E
Site 43
S352
P
Y
D
S
K
K
P
S
P
C
E
F
I
N
T
Site 44
Y410
Q
W
D
G
E
K
L
Y
Q
E
A
R
K
I
L
Site 45
Y445
M
Q
K
W
I
P
P
Y
Q
G
Y
S
E
S
V
Site 46
S449
I
P
P
Y
Q
G
Y
S
E
S
V
D
P
R
I
Site 47
S451
P
Y
Q
G
Y
S
E
S
V
D
P
R
I
S
N
Site 48
S474
G
H
L
E
V
P
S
S
M
F
R
L
D
E
N
Site 49
Y482
M
F
R
L
D
E
N
Y
Q
P
W
G
P
E
P
Site 50
S521
R
G
L
L
A
K
K
S
K
L
M
K
Q
N
K
Site 51
T542
R
N
K
L
F
Q
P
T
H
R
I
H
G
F
D
Site 52
T555
F
D
L
A
A
I
N
T
Q
R
C
R
D
H
G
Site 53
Y566
R
D
H
G
Q
P
G
Y
N
S
W
R
A
F
C
Site 54
S576
W
R
A
F
C
D
L
S
Q
P
Q
T
L
E
E
Site 55
T580
C
D
L
S
Q
P
Q
T
L
E
E
L
N
T
V
Site 56
T586
Q
T
L
E
E
L
N
T
V
L
K
S
K
M
L
Site 57
Y601
A
K
K
L
L
G
L
Y
G
T
P
D
N
I
D
Site 58
S660
F
T
N
E
Q
K
D
S
L
Q
K
M
S
F
S
Site 59
S665
K
D
S
L
Q
K
M
S
F
S
R
L
V
C
D
Site 60
T674
S
R
L
V
C
D
N
T
R
I
T
K
V
P
R
Site 61
T677
V
C
D
N
T
R
I
T
K
V
P
R
D
P
F
Site 62
S705
A
I
D
K
L
D
L
S
P
W
A
S
V
K
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation