PhosphoNET

           
Protein Info 
   
Short Name:  BGN
Full Name:  Biglycan
Alias:  Bone/cartilage proteoglycan I;PG-S1
Type: 
Mass (Da):  41654
Number AA:  368
UniProt ID:  P21810
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T46EEASGADTSGVLDPD
Site 2S54SGVLDPDSVTPTYSA
Site 3T58DPDSVTPTYSAMCPF
Site 4Y59PDSVTPTYSAMCPFG
Site 5S77HLRVVQCSDLGLKSV
Site 6S83CSDLGLKSVPKEISP
Site 7S89KSVPKEISPDTTLLD
Site 8T92PKEISPDTTLLDLQN
Site 9T93KEISPDTTLLDLQNN
Site 10S135KIHEKAFSPLRKLQK
Site 11Y144LRKLQKLYISKNHLV
Site 12S180KVPKGVFSGLRNMNC
Site 13S198GGNPLENSGFEPGAF
Site 14Y212FDGLKLNYLRISEAK
Site 15S216KLNYLRISEAKLTGI
Site 16T221RISEAKLTGIPKDLP
Site 17S253LEDLLRYSKLYRLGL
Site 18Y256LLRYSKLYRLGLGHN
Site 19S274MIENGSLSFLPTLRE
Site 20S294NKLARVPSGLPDLKL
Site 21Y332FGVKRAYYNGISLFN
Site 22Y344LFNNPVPYWEVQPAT
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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