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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAOA
Full Name:
Amine oxidase [flavin-containing] A
Alias:
AOFA; MAO-A; Monoamine oxidase A; Monoamine oxidase type A
Type:
EC 1.4.3.4; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - histidine; Oxidoreductase; Amino Acid Metabolism - arginine and proline; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tyrosine
Mass (Da):
59680
Number AA:
UniProt ID:
P21397
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005741
Uniprot
OncoNet
Molecular Function:
GO:0008131
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007610
GO:0042135
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T52
R
D
R
V
G
G
R
T
Y
T
I
R
N
E
H
Site 2
Y53
D
R
V
G
G
R
T
Y
T
I
R
N
E
H
V
Site 3
T54
R
V
G
G
R
T
Y
T
I
R
N
E
H
V
D
Site 4
Y62
I
R
N
E
H
V
D
Y
V
D
V
G
G
A
Y
Site 5
Y69
Y
V
D
V
G
G
A
Y
V
G
P
T
Q
N
R
Site 6
T73
G
G
A
Y
V
G
P
T
Q
N
R
I
L
R
L
Site 7
S81
Q
N
R
I
L
R
L
S
K
E
L
G
I
E
T
Site 8
Y89
K
E
L
G
I
E
T
Y
K
V
N
V
S
E
R
Site 9
S94
E
T
Y
K
V
N
V
S
E
R
L
V
Q
Y
V
Site 10
Y100
V
S
E
R
L
V
Q
Y
V
K
G
K
T
Y
P
Site 11
T105
V
Q
Y
V
K
G
K
T
Y
P
F
R
G
A
F
Site 12
Y106
Q
Y
V
K
G
K
T
Y
P
F
R
G
A
F
P
Site 13
Y124
N
P
I
A
Y
L
D
Y
N
N
L
W
R
T
I
Site 14
T140
N
M
G
K
E
I
P
T
D
A
P
W
E
A
Q
Site 15
S209
G
G
T
T
R
I
F
S
V
T
N
G
G
Q
E
Site 16
T211
T
T
R
I
F
S
V
T
N
G
G
Q
E
R
K
Site 17
T245
V
K
L
N
H
P
V
T
H
V
D
Q
S
S
D
Site 18
S251
V
T
H
V
D
Q
S
S
D
N
I
I
I
E
T
Site 19
T258
S
D
N
I
I
I
E
T
L
N
H
E
H
Y
E
Site 20
Y264
E
T
L
N
H
E
H
Y
E
C
K
Y
V
I
N
Site 21
Y268
H
E
H
Y
E
C
K
Y
V
I
N
A
I
P
P
Site 22
S334
E
D
E
D
A
P
I
S
I
T
L
D
D
T
K
Site 23
T340
I
S
I
T
L
D
D
T
K
P
D
G
S
L
P
Site 24
S345
D
D
T
K
P
D
G
S
L
P
A
I
M
G
F
Site 25
Y377
K
K
K
I
C
E
L
Y
A
K
V
L
G
S
Q
Site 26
S383
L
Y
A
K
V
L
G
S
Q
E
A
L
H
P
V
Site 27
Y392
E
A
L
H
P
V
H
Y
E
E
K
N
W
C
E
Site 28
Y407
E
Q
Y
S
G
G
C
Y
T
A
Y
F
P
P
G
Site 29
Y419
P
P
G
I
M
T
Q
Y
G
R
V
I
R
Q
P
Site 30
T489
P
A
V
E
I
T
H
T
F
W
E
R
N
L
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation