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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NTF3
Full Name:
Neurotrophin-3
Alias:
HDNF; Nerve growth factor 2; Neurotrophic factor; NGF2; NGF-2; NT3; NT-3
Type:
Extracellular region, Plasma membrane, Cytoplasmic membrane-bound vesicle protein
Mass (Da):
29355
Number AA:
257
UniProt ID:
P20783
International Prot ID:
IPI00025474
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0008083
GO:0005165
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
G
N
N
M
D
Q
R
S
L
P
E
D
S
L
N
Site 2
S30
Q
R
S
L
P
E
D
S
L
N
S
L
I
I
K
Site 3
S49
D
I
L
K
N
K
L
S
K
Q
M
V
D
V
K
Site 4
Y59
M
V
D
V
K
E
N
Y
Q
S
T
L
P
K
A
Site 5
S61
D
V
K
E
N
Y
Q
S
T
L
P
K
A
E
A
Site 6
S80
E
R
G
G
P
A
K
S
A
F
Q
P
V
I
A
Site 7
Y99
L
L
R
Q
Q
R
R
Y
N
S
P
R
V
L
L
Site 8
S101
R
Q
Q
R
R
Y
N
S
P
R
V
L
L
S
D
Site 9
S107
N
S
P
R
V
L
L
S
D
S
T
P
L
E
P
Site 10
S109
P
R
V
L
L
S
D
S
T
P
L
E
P
P
P
Site 11
T110
R
V
L
L
S
D
S
T
P
L
E
P
P
P
L
Site 12
Y118
P
L
E
P
P
P
L
Y
L
M
E
D
Y
V
G
Site 13
Y123
P
L
Y
L
M
E
D
Y
V
G
S
P
V
V
A
Site 14
S126
L
M
E
D
Y
V
G
S
P
V
V
A
N
R
T
Site 15
T133
S
P
V
V
A
N
R
T
S
R
R
K
R
Y
A
Site 16
S134
P
V
V
A
N
R
T
S
R
R
K
R
Y
A
E
Site 17
Y139
R
T
S
R
R
K
R
Y
A
E
H
K
S
H
R
Site 18
S144
K
R
Y
A
E
H
K
S
H
R
G
E
Y
S
V
Site 19
Y149
H
K
S
H
R
G
E
Y
S
V
C
D
S
E
S
Site 20
S150
K
S
H
R
G
E
Y
S
V
C
D
S
E
S
L
Site 21
S154
G
E
Y
S
V
C
D
S
E
S
L
W
V
T
D
Site 22
S156
Y
S
V
C
D
S
E
S
L
W
V
T
D
K
S
Site 23
T160
D
S
E
S
L
W
V
T
D
K
S
S
A
I
D
Site 24
S163
S
L
W
V
T
D
K
S
S
A
I
D
I
R
G
Site 25
T174
D
I
R
G
H
Q
V
T
V
L
G
E
I
K
T
Site 26
S184
G
E
I
K
T
G
N
S
P
V
K
Q
Y
F
Y
Site 27
Y189
G
N
S
P
V
K
Q
Y
F
Y
E
T
R
C
K
Site 28
Y191
S
P
V
K
Q
Y
F
Y
E
T
R
C
K
E
A
Site 29
T222
S
Q
C
K
T
S
Q
T
Y
V
R
A
L
T
S
Site 30
Y223
Q
C
K
T
S
Q
T
Y
V
R
A
L
T
S
E
Site 31
T228
Q
T
Y
V
R
A
L
T
S
E
N
N
K
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation