KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HOXA5
Full Name:
Homeobox protein Hox-A5
Alias:
Homeobox A5; HOX1; HOX1.3; HOX1C; Hox-1C; HXA5
Type:
Mass (Da):
29350
Number AA:
270
UniProt ID:
P20719
International Prot ID:
IPI00302291
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
V
N
S
F
C
G
R
Y
P
N
G
P
D
Y
Q
Site 2
Y19
R
Y
P
N
G
P
D
Y
Q
L
H
N
Y
G
D
Site 3
Y24
P
D
Y
Q
L
H
N
Y
G
D
H
S
S
V
S
Site 4
S28
L
H
N
Y
G
D
H
S
S
V
S
E
Q
F
R
Site 5
S29
H
N
Y
G
D
H
S
S
V
S
E
Q
F
R
D
Site 6
S31
Y
G
D
H
S
S
V
S
E
Q
F
R
D
S
A
Site 7
S37
V
S
E
Q
F
R
D
S
A
S
M
H
S
G
R
Site 8
S39
E
Q
F
R
D
S
A
S
M
H
S
G
R
Y
G
Site 9
S42
R
D
S
A
S
M
H
S
G
R
Y
G
Y
G
Y
Site 10
Y45
A
S
M
H
S
G
R
Y
G
Y
G
Y
N
G
M
Site 11
Y47
M
H
S
G
R
Y
G
Y
G
Y
N
G
M
D
L
Site 12
Y49
S
G
R
Y
G
Y
G
Y
N
G
M
D
L
S
V
Site 13
S55
G
Y
N
G
M
D
L
S
V
G
R
S
G
S
G
Site 14
S59
M
D
L
S
V
G
R
S
G
S
G
H
F
G
S
Site 15
S61
L
S
V
G
R
S
G
S
G
H
F
G
S
G
E
Site 16
S66
S
G
S
G
H
F
G
S
G
E
R
A
R
S
Y
Site 17
S72
G
S
G
E
R
A
R
S
Y
A
A
S
A
S
A
Site 18
Y73
S
G
E
R
A
R
S
Y
A
A
S
A
S
A
A
Site 19
S76
R
A
R
S
Y
A
A
S
A
S
A
A
P
A
E
Site 20
Y86
A
A
P
A
E
P
R
Y
S
Q
P
A
T
S
T
Site 21
S87
A
P
A
E
P
R
Y
S
Q
P
A
T
S
T
H
Site 22
T91
P
R
Y
S
Q
P
A
T
S
T
H
S
P
Q
P
Site 23
S92
R
Y
S
Q
P
A
T
S
T
H
S
P
Q
P
D
Site 24
T93
Y
S
Q
P
A
T
S
T
H
S
P
Q
P
D
P
Site 25
S95
Q
P
A
T
S
T
H
S
P
Q
P
D
P
L
P
Site 26
S104
Q
P
D
P
L
P
C
S
A
V
A
P
S
P
G
Site 27
S109
P
C
S
A
V
A
P
S
P
G
S
D
S
H
H
Site 28
S112
A
V
A
P
S
P
G
S
D
S
H
H
G
G
K
Site 29
S114
A
P
S
P
G
S
D
S
H
H
G
G
K
N
S
Site 30
S121
S
H
H
G
G
K
N
S
L
S
N
S
S
G
A
Site 31
S123
H
G
G
K
N
S
L
S
N
S
S
G
A
S
A
Site 32
S125
G
K
N
S
L
S
N
S
S
G
A
S
A
D
A
Site 33
S129
L
S
N
S
S
G
A
S
A
D
A
G
S
T
H
Site 34
S134
G
A
S
A
D
A
G
S
T
H
I
S
S
R
E
Site 35
S138
D
A
G
S
T
H
I
S
S
R
E
G
V
G
T
Site 36
S139
A
G
S
T
H
I
S
S
R
E
G
V
G
T
A
Site 37
T145
S
S
R
E
G
V
G
T
A
S
G
A
E
E
D
Site 38
S147
R
E
G
V
G
T
A
S
G
A
E
E
D
A
P
Site 39
S156
A
E
E
D
A
P
A
S
S
E
Q
A
S
A
Q
Site 40
S157
E
E
D
A
P
A
S
S
E
Q
A
S
A
Q
S
Site 41
S161
P
A
S
S
E
Q
A
S
A
Q
S
E
P
S
P
Site 42
S167
A
S
A
Q
S
E
P
S
P
A
P
P
A
Q
P
Site 43
Y177
P
P
A
Q
P
Q
I
Y
P
W
M
R
K
L
H
Site 44
T200
P
E
G
K
R
A
R
T
A
Y
T
R
Y
Q
T
Site 45
Y202
G
K
R
A
R
T
A
Y
T
R
Y
Q
T
L
E
Site 46
T203
K
R
A
R
T
A
Y
T
R
Y
Q
T
L
E
L
Site 47
T207
T
A
Y
T
R
Y
Q
T
L
E
L
E
K
E
F
Site 48
Y219
K
E
F
H
F
N
R
Y
L
T
R
R
R
R
I
Site 49
T221
F
H
F
N
R
Y
L
T
R
R
R
R
I
E
I
Site 50
S258
K
K
D
N
K
L
K
S
M
S
M
A
A
A
G
Site 51
S260
D
N
K
L
K
S
M
S
M
A
A
A
G
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation