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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MX1
Full Name:
Interferon-induced GTP-binding protein Mx1
Alias:
IFI-78K; Interferon-induced protein p78; Interferon-regulated resistance GTP-binding protein MxA; MxA; Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78; Myxovirus resistance protein 1
Type:
G protein; G protein, monomeric (non-Rab)
Mass (Da):
75520
Number AA:
662
UniProt ID:
P20591
International Prot ID:
IPI00167949
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006952
GO:0006917
GO:0009615
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
K
A
D
P
A
A
A
S
H
P
L
L
L
N
G
Site 2
T27
L
L
L
N
G
D
A
T
V
A
Q
K
N
P
G
Site 3
S35
V
A
Q
K
N
P
G
S
V
A
E
N
N
L
C
Site 4
S43
V
A
E
N
N
L
C
S
Q
Y
E
E
K
V
R
Site 5
Y45
E
N
N
L
C
S
Q
Y
E
E
K
V
R
P
C
Site 6
S81
A
V
I
G
D
Q
S
S
G
K
S
S
V
L
E
Site 7
S84
G
D
Q
S
S
G
K
S
S
V
L
E
A
L
S
Site 8
S85
D
Q
S
S
G
K
S
S
V
L
E
A
L
S
G
Site 9
Y126
K
W
R
G
K
V
S
Y
Q
D
Y
E
I
E
I
Site 10
Y129
G
K
V
S
Y
Q
D
Y
E
I
E
I
S
D
A
Site 11
S134
Q
D
Y
E
I
E
I
S
D
A
S
E
V
E
K
Site 12
S137
E
I
E
I
S
D
A
S
E
V
E
K
E
I
N
Site 13
T163
G
I
S
H
E
L
I
T
L
E
I
S
S
R
D
Site 14
T183
L
I
D
L
P
G
I
T
R
V
A
V
G
N
Q
Site 15
Y196
N
Q
P
A
D
I
G
Y
K
I
K
T
L
I
K
Site 16
T200
D
I
G
Y
K
I
K
T
L
I
K
K
Y
I
Q
Site 17
Y205
I
K
T
L
I
K
K
Y
I
Q
R
Q
E
T
I
Site 18
T242
V
D
P
E
G
D
R
T
I
G
I
L
T
K
P
Site 19
T256
P
D
L
V
D
K
G
T
E
D
K
V
V
D
V
Site 20
S291
Q
E
I
Q
D
Q
L
S
L
S
E
A
L
Q
R
Site 21
S293
I
Q
D
Q
L
S
L
S
E
A
L
Q
R
E
K
Site 22
Y308
I
F
F
E
N
H
P
Y
F
R
D
L
L
E
E
Site 23
T354
K
E
T
H
Q
R
I
T
E
E
L
Q
K
Y
G
Site 24
Y360
I
T
E
E
L
Q
K
Y
G
V
D
I
P
E
D
Site 25
T387
N
A
F
N
Q
D
I
T
A
L
M
Q
G
E
E
Site 26
T405
E
E
D
I
R
L
F
T
R
L
R
H
E
F
H
Site 27
Y451
E
L
P
G
F
V
N
Y
R
T
F
E
T
I
V
Site 28
T453
P
G
F
V
N
Y
R
T
F
E
T
I
V
K
Q
Site 29
S488
R
L
A
F
T
D
V
S
I
K
N
F
E
E
F
Site 30
Y538
V
Y
C
Q
D
Q
V
Y
R
G
A
L
Q
K
V
Site 31
S558
E
E
E
K
K
K
K
S
W
D
F
G
A
F
Q
Site 32
S566
W
D
F
G
A
F
Q
S
S
S
A
T
D
S
S
Site 33
S567
D
F
G
A
F
Q
S
S
S
A
T
D
S
S
M
Site 34
S568
F
G
A
F
Q
S
S
S
A
T
D
S
S
M
E
Site 35
T570
A
F
Q
S
S
S
A
T
D
S
S
M
E
E
I
Site 36
S572
Q
S
S
S
A
T
D
S
S
M
E
E
I
F
Q
Site 37
S573
S
S
S
A
T
D
S
S
M
E
E
I
F
Q
H
Site 38
S589
M
A
Y
H
Q
E
A
S
K
R
I
S
S
H
I
Site 39
S593
Q
E
A
S
K
R
I
S
S
H
I
P
L
I
I
Site 40
S594
E
A
S
K
R
I
S
S
H
I
P
L
I
I
Q
Site 41
T625
Q
L
L
Q
D
K
D
T
Y
S
W
L
L
K
E
Site 42
Y626
L
L
Q
D
K
D
T
Y
S
W
L
L
K
E
R
Site 43
S627
L
Q
D
K
D
T
Y
S
W
L
L
K
E
R
S
Site 44
S634
S
W
L
L
K
E
R
S
D
T
S
D
K
R
K
Site 45
T636
L
L
K
E
R
S
D
T
S
D
K
R
K
F
L
Site 46
S637
L
K
E
R
S
D
T
S
D
K
R
K
F
L
K
Site 47
T651
K
E
R
L
A
R
L
T
Q
A
R
R
R
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation