PhosphoNET

           
Protein Info 
   
Short Name:  TNFRSF1B
Full Name:  Tumor necrosis factor receptor superfamily member 1B
Alias:  CD120b; Etanercept; Membrane form; P75; P75 TNF receptor; P75TNFR; P80 TNF-alpha receptor; TBP-2; TBPII; TNFBR; TNFR2; TNF-R2; TNF-R75; TNFR80; TNF-R-II; TNR1B; Tumor necrosis factor beta receptor; Tumor necrosis factor binding protein 2; Tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1b; Tumor necrosis factor receptor type II
Type:  Receptor, miscellaneous
Mass (Da):  48291
Number AA:  461
UniProt ID:  P20333
International Prot ID:  Isoform1 - IPI00023501
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005576  GO:0016021  GO:0045121 Uniprot OncoNet
Molecular Function:  GO:0005031     PhosphoSite+ KinaseNET
Biological Process:  GO:0006915     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S221VHLPQPVSTRSQHTQ
Site 2T311PADKARGTQGPEQQH
Site 3T322EQQHLLITAPSSSSS
Site 4S325HLLITAPSSSSSSLE
Site 5S327LITAPSSSSSSLESS
Site 6S328ITAPSSSSSSLESSA
Site 7S329TAPSSSSSSLESSAS
Site 8S330APSSSSSSLESSASA
Site 9S333SSSSSLESSASALDR
Site 10S334SSSSLESSASALDRR
Site 11S336SSLESSASALDRRAP
Site 12T344ALDRRAPTRNQPQAP
Site 13S364GAGEARASTGSSDSS
Site 14T365AGEARASTGSSDSSP
Site 15S367EARASTGSSDSSPGG
Site 16S368ARASTGSSDSSPGGH
Site 17S370ASTGSSDSSPGGHGT
Site 18S371STGSSDSSPGGHGTQ
Site 19T377SSPGGHGTQVNVTCI
Site 20S389TCIVNVCSSSDHSSQ
Site 21S391IVNVCSSSDHSSQCS
Site 22S394VCSSSDHSSQCSSQA
Site 23S395CSSSDHSSQCSSQAS
Site 24S398SDHSSQCSSQASSTM
Site 25S399DHSSQCSSQASSTMG
Site 26S402SQCSSQASSTMGDTD
Site 27S403QCSSQASSTMGDTDS
Site 28T408ASSTMGDTDSSPSES
Site 29S410STMGDTDSSPSESPK
Site 30S411TMGDTDSSPSESPKD
Site 31S413GDTDSSPSESPKDEQ
Site 32S415TDSSPSESPKDEQVP
Site 33S424KDEQVPFSKEECAFR
Site 34S432KEECAFRSQLETPET
Site 35T436AFRSQLETPETLLGS
Site 36T439SQLETPETLLGSTEE
Site 37S443TPETLLGSTEEKPLP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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