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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CD22
Full Name:
B-cell receptor CD22
Alias:
B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 molecule; Leu-14; SIGLEC2; Siglec-2
Type:
Cell surface
Mass (Da):
95348
Number AA:
847
UniProt ID:
P20273
International Prot ID:
IPI00218390
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005529
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S654
E
P
V
K
V
Q
H
S
G
A
Y
W
C
Q
G
Site 2
Y657
K
V
Q
H
S
G
A
Y
W
C
Q
G
T
N
S
Site 3
T715
L
Q
R
R
W
K
R
T
Q
S
Q
Q
G
L
Q
Site 4
S717
R
R
W
K
R
T
Q
S
Q
Q
G
L
Q
E
N
Site 5
S725
Q
Q
G
L
Q
E
N
S
S
G
Q
S
F
F
V
Site 6
S726
Q
G
L
Q
E
N
S
S
G
Q
S
F
F
V
R
Site 7
S729
Q
E
N
S
S
G
Q
S
F
F
V
R
N
K
K
Site 8
S743
K
V
R
R
A
P
L
S
E
G
P
H
S
L
G
Site 9
S748
P
L
S
E
G
P
H
S
L
G
C
Y
N
P
M
Site 10
Y752
G
P
H
S
L
G
C
Y
N
P
M
M
E
D
G
Site 11
S761
P
M
M
E
D
G
I
S
Y
T
T
L
R
F
P
Site 12
Y762
M
M
E
D
G
I
S
Y
T
T
L
R
F
P
E
Site 13
T763
M
E
D
G
I
S
Y
T
T
L
R
F
P
E
M
Site 14
T764
E
D
G
I
S
Y
T
T
L
R
F
P
E
M
N
Site 15
T775
P
E
M
N
I
P
R
T
G
D
A
E
S
S
E
Site 16
S780
P
R
T
G
D
A
E
S
S
E
M
Q
R
P
P
Site 17
T793
P
P
P
D
C
D
D
T
V
T
Y
S
A
L
H
Site 18
T795
P
D
C
D
D
T
V
T
Y
S
A
L
H
K
R
Site 19
Y796
D
C
D
D
T
V
T
Y
S
A
L
H
K
R
Q
Site 20
Y807
H
K
R
Q
V
G
D
Y
E
N
V
I
P
D
F
Site 21
Y822
P
E
D
E
G
I
H
Y
S
E
L
I
Q
F
G
Site 22
S823
E
D
E
G
I
H
Y
S
E
L
I
Q
F
G
V
Site 23
Y842
Q
A
Q
E
N
V
D
Y
V
I
L
K
H
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation