KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TCN1
Full Name:
Transcobalamin-1
Alias:
Transcobalamin I
Type:
Mass (Da):
48207
Number AA:
433
UniProt ID:
P20061
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
C
E
V
S
E
E
N
Y
I
R
L
K
P
L
L
Site 2
T42
R
L
K
P
L
L
N
T
M
I
Q
S
N
Y
N
Site 3
S46
L
L
N
T
M
I
Q
S
N
Y
N
R
G
T
S
Site 4
Y48
N
T
M
I
Q
S
N
Y
N
R
G
T
S
A
V
Site 5
T52
Q
S
N
Y
N
R
G
T
S
A
V
N
V
V
L
Site 6
S53
S
N
Y
N
R
G
T
S
A
V
N
V
V
L
S
Site 7
Y81
K
M
I
Q
Q
I
K
Y
N
V
K
S
R
L
S
Site 8
S85
Q
I
K
Y
N
V
K
S
R
L
S
D
V
S
S
Site 9
S88
Y
N
V
K
S
R
L
S
D
V
S
S
G
E
L
Site 10
S91
K
S
R
L
S
D
V
S
S
G
E
L
A
L
I
Site 11
Y114
N
A
E
E
N
L
I
Y
D
Y
H
L
I
D
K
Site 12
Y116
E
E
N
L
I
Y
D
Y
H
L
I
D
K
L
E
Site 13
T139
N
M
E
A
H
N
G
T
P
L
T
N
Y
Y
Q
Site 14
T142
A
H
N
G
T
P
L
T
N
Y
Y
Q
L
S
L
Site 15
Y144
N
G
T
P
L
T
N
Y
Y
Q
L
S
L
D
V
Site 16
T171
A
E
V
V
N
H
F
T
P
E
N
K
N
Y
Y
Site 17
Y177
F
T
P
E
N
K
N
Y
Y
F
G
S
Q
F
S
Site 18
Y178
T
P
E
N
K
N
Y
Y
F
G
S
Q
F
S
V
Site 19
S181
N
K
N
Y
Y
F
G
S
Q
F
S
V
D
T
G
Site 20
S213
Q
I
K
A
D
E
G
S
L
K
N
I
S
I
Y
Site 21
S218
E
G
S
L
K
N
I
S
I
Y
T
K
S
L
V
Site 22
Y220
S
L
K
N
I
S
I
Y
T
K
S
L
V
E
K
Site 23
S230
S
L
V
E
K
I
L
S
E
K
K
E
N
G
L
Site 24
T241
E
N
G
L
I
G
N
T
F
S
T
G
E
A
M
Site 25
Y257
A
L
F
V
S
S
D
Y
Y
N
E
N
D
W
N
Site 26
Y258
L
F
V
S
S
D
Y
Y
N
E
N
D
W
N
C
Site 27
S277
N
T
V
L
T
E
I
S
Q
G
A
F
S
N
P
Site 28
S306
F
L
D
I
N
K
D
S
S
C
V
S
A
S
G
Site 29
S307
L
D
I
N
K
D
S
S
C
V
S
A
S
G
N
Site 30
S310
N
K
D
S
S
C
V
S
A
S
G
N
F
N
I
Site 31
S312
D
S
S
C
V
S
A
S
G
N
F
N
I
S
A
Site 32
S318
A
S
G
N
F
N
I
S
A
D
E
P
I
T
V
Site 33
T324
I
S
A
D
E
P
I
T
V
T
P
P
D
S
Q
Site 34
T326
A
D
E
P
I
T
V
T
P
P
D
S
Q
S
Y
Site 35
S330
I
T
V
T
P
P
D
S
Q
S
Y
I
S
V
N
Site 36
S332
V
T
P
P
D
S
Q
S
Y
I
S
V
N
Y
S
Site 37
Y333
T
P
P
D
S
Q
S
Y
I
S
V
N
Y
S
V
Site 38
S335
P
D
S
Q
S
Y
I
S
V
N
Y
S
V
R
I
Site 39
S339
S
Y
I
S
V
N
Y
S
V
R
I
N
E
T
Y
Site 40
T348
R
I
N
E
T
Y
F
T
N
V
T
V
L
N
G
Site 41
Y385
E
E
R
S
W
G
P
Y
I
T
C
I
Q
G
L
Site 42
Y401
A
N
N
N
D
R
T
Y
W
E
L
L
S
G
G
Site 43
S406
R
T
Y
W
E
L
L
S
G
G
E
P
L
S
Q
Site 44
S412
L
S
G
G
E
P
L
S
Q
G
A
G
S
Y
V
Site 45
S417
P
L
S
Q
G
A
G
S
Y
V
V
R
N
G
E
Site 46
Y418
L
S
Q
G
A
G
S
Y
V
V
R
N
G
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation