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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABP1
Full Name:
Amiloride-sensitive amine oxidase [copper-containing]
Alias:
Amiloride-binding protein;Histaminase;Kidney amine oxidase
Type:
Mass (Da):
85378
Number AA:
751
UniProt ID:
P19801
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
Q
T
A
M
A
E
P
S
P
G
T
L
P
R
K
Site 2
T25
M
A
E
P
S
P
G
T
L
P
R
K
A
G
V
Site 3
S46
Q
E
L
K
A
V
H
S
F
L
W
S
K
K
E
Site 4
S50
A
V
H
S
F
L
W
S
K
K
E
L
R
L
Q
Site 5
S59
K
E
L
R
L
Q
P
S
S
T
T
T
M
A
K
Site 6
S60
E
L
R
L
Q
P
S
S
T
T
T
M
A
K
N
Site 7
T61
L
R
L
Q
P
S
S
T
T
T
M
A
K
N
T
Site 8
T62
R
L
Q
P
S
S
T
T
T
M
A
K
N
T
V
Site 9
T63
L
Q
P
S
S
T
T
T
M
A
K
N
T
V
F
Site 10
Y80
E
M
L
L
P
K
K
Y
H
V
L
R
F
L
D
Site 11
Y124
G
P
L
P
G
P
C
Y
M
R
A
L
S
P
R
Site 12
S129
P
C
Y
M
R
A
L
S
P
R
P
G
Y
Q
S
Site 13
Y134
A
L
S
P
R
P
G
Y
Q
S
S
W
A
S
R
Site 14
S136
S
P
R
P
G
Y
Q
S
S
W
A
S
R
P
I
Site 15
S137
P
R
P
G
Y
Q
S
S
W
A
S
R
P
I
S
Site 16
S140
G
Y
Q
S
S
W
A
S
R
P
I
S
T
A
E
Site 17
S144
S
W
A
S
R
P
I
S
T
A
E
Y
A
L
L
Site 18
Y152
T
A
E
Y
A
L
L
Y
H
T
L
Q
E
A
T
Site 19
T185
H
D
R
C
L
A
F
T
D
V
A
P
R
G
V
Site 20
S194
V
A
P
R
G
V
A
S
G
Q
R
R
S
W
L
Site 21
S199
V
A
S
G
Q
R
R
S
W
L
I
I
Q
R
Y
Site 22
Y210
I
Q
R
Y
V
E
G
Y
F
L
H
P
T
G
L
Site 23
S225
E
L
L
V
D
H
G
S
T
D
A
G
H
W
A
Site 24
Y243
V
W
Y
N
G
K
F
Y
G
S
P
E
E
L
A
Site 25
S245
Y
N
G
K
F
Y
G
S
P
E
E
L
A
R
K
Site 26
Y253
P
E
E
L
A
R
K
Y
A
D
G
E
V
D
V
Site 27
S275
P
G
G
K
G
H
D
S
T
E
E
P
P
L
F
Site 28
T276
G
G
K
G
H
D
S
T
E
E
P
P
L
F
S
Site 29
S284
E
E
P
P
L
F
S
S
H
K
P
R
G
D
F
Site 30
S293
K
P
R
G
D
F
P
S
P
I
H
V
S
G
P
Site 31
S298
F
P
S
P
I
H
V
S
G
P
R
L
V
Q
P
Site 32
Y348
F
G
G
E
R
I
A
Y
E
V
S
V
Q
E
A
Site 33
T363
V
A
L
Y
G
G
H
T
P
A
G
M
Q
T
K
Site 34
Y371
P
A
G
M
Q
T
K
Y
L
D
V
G
W
G
L
Site 35
Y403
T
F
L
D
T
F
H
Y
Y
D
A
D
D
P
V
Site 36
Y404
F
L
D
T
F
H
Y
Y
D
A
D
D
P
V
H
Site 37
Y412
D
A
D
D
P
V
H
Y
P
R
A
L
C
L
F
Site 38
S433
P
L
R
R
H
F
N
S
N
F
K
G
G
F
N
Site 39
Y442
F
K
G
G
F
N
F
Y
A
G
L
K
G
Q
V
Site 40
T455
Q
V
L
V
L
R
T
T
S
T
V
Y
N
Y
D
Site 41
Y484
A
K
M
H
A
T
G
Y
V
H
A
T
F
Y
T
Site 42
Y490
G
Y
V
H
A
T
F
Y
T
P
E
G
L
R
H
Site 43
T491
Y
V
H
A
T
F
Y
T
P
E
G
L
R
H
G
Site 44
T499
P
E
G
L
R
H
G
T
R
L
H
T
H
L
I
Site 45
T503
R
H
G
T
R
L
H
T
H
L
I
G
N
I
H
Site 46
S528
D
V
A
G
T
K
N
S
F
Q
T
L
Q
M
K
Site 47
S544
E
N
I
T
N
P
W
S
P
R
H
R
V
V
Q
Site 48
T553
R
H
R
V
V
Q
P
T
L
E
Q
T
Q
Y
S
Site 49
Y559
P
T
L
E
Q
T
Q
Y
S
W
E
R
Q
A
A
Site 50
S560
T
L
E
Q
T
Q
Y
S
W
E
R
Q
A
A
F
Site 51
Y576
F
K
R
K
L
P
K
Y
L
L
F
T
S
P
Q
Site 52
S581
P
K
Y
L
L
F
T
S
P
Q
E
N
P
W
G
Site 53
S599
T
Y
R
L
Q
I
H
S
M
A
D
Q
V
L
P
Site 54
Y620
Q
A
I
T
W
A
R
Y
P
L
A
V
T
K
Y
Site 55
Y627
Y
P
L
A
V
T
K
Y
R
E
S
E
L
C
S
Site 56
S630
A
V
T
K
Y
R
E
S
E
L
C
S
S
S
I
Site 57
S634
Y
R
E
S
E
L
C
S
S
S
I
Y
H
Q
N
Site 58
S635
R
E
S
E
L
C
S
S
S
I
Y
H
Q
N
D
Site 59
S636
E
S
E
L
C
S
S
S
I
Y
H
Q
N
D
P
Site 60
Y638
E
L
C
S
S
S
I
Y
H
Q
N
D
P
W
H
Site 61
S679
G
F
L
H
I
P
H
S
E
D
I
P
N
T
A
Site 62
T685
H
S
E
D
I
P
N
T
A
T
P
G
N
S
V
Site 63
T687
E
D
I
P
N
T
A
T
P
G
N
S
V
G
F
Site 64
S707
N
F
F
P
E
D
P
S
L
A
S
R
D
T
V
Site 65
T713
P
S
L
A
S
R
D
T
V
I
V
W
P
R
D
Site 66
Y725
P
R
D
N
G
P
N
Y
V
Q
R
W
I
P
E
Site 67
S737
I
P
E
D
R
D
C
S
M
P
P
P
F
S
Y
Site 68
S743
C
S
M
P
P
P
F
S
Y
N
G
T
Y
R
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation