PhosphoNET

           
Protein Info 
   
Short Name:  KRT4
Full Name:  Keratin, type II cytoskeletal 4
Alias:  CK4; CK-4; CYK4; Cytokeratin 4; Cytokeratin-4; K2C4; Keratin 4; Keratin-4
Type:  Cytoskeletal protein
Mass (Da):  57285
Number AA:  534
UniProt ID:  P19013
International Prot ID:  IPI00290078
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0045095     Uniprot OncoNet
Molecular Function:  GO:0005198     PhosphoSite+ KinaseNET
Biological Process:  GO:0007010  GO:0030855  GO:0050680 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16RGGPRGFSCGSAIVG
Site 2S19PRGFSCGSAIVGGGK
Site 3S31GGKRGAFSSVSMSGG
Site 4S32GKRGAFSSVSMSGGA
Site 5S34RGAFSSVSMSGGAGR
Site 6S43SGGAGRCSSGGFGSR
Site 7S44GGAGRCSSGGFGSRS
Site 8S49CSSGGFGSRSLYNLR
Site 9S51SGGFGSRSLYNLRGN
Site 10Y53GFGSRSLYNLRGNKS
Site 11S60YNLRGNKSISMSVAG
Site 12S62LRGNKSISMSVAGSR
Site 13S64GNKSISMSVAGSRQG
Site 14S106FGGGFGGSFSGKGGP
Site 15S108GGFGGSFSGKGGPGF
Site 16S164LLNNKFASFIDKVQF
Site 17T190WNLLQQQTTTTSSKN
Site 18T191NLLQQQTTTTSSKNL
Site 19S195QQTTTTSSKNLEPLF
Site 20Y205LEPLFETYLSVLRKQ
Site 21S207PLFETYLSVLRKQLD
Site 22T215VLRKQLDTLGNDKGR
Site 23S225NDKGRLQSELKTMQD
Site 24T229RLQSELKTMQDSVED
Site 25S233ELKTMQDSVEDFKTK
Site 26T239DSVEDFKTKYEEEIN
Site 27Y241VEDFKTKYEEEINKR
Site 28Y266KKDVDAAYLNKVELE
Site 29S278ELEAKVDSLNDEINF
Site 30S295VLYDAELSQMQTHVS
Site 31T299AELSQMQTHVSDTSV
Site 32S302SQMQTHVSDTSVVLS
Site 33T304MQTHVSDTSVVLSMD
Site 34S305QTHVSDTSVVLSMDN
Site 35S309SDTSVVLSMDNNRNL
Site 36S320NRNLDLDSIIAEVRA
Site 37Y329IAEVRAQYEEIAQRS
Site 38Y344KAEAEALYQTKVQQL
Site 39T346EAEALYQTKVQQLQI
Site 40S367DNLKNTKSEIAELNR
Site 41T392NIKKQCQTLQVSVAD
Site 42S396QCQTLQVSVADAEQR
Site 43S413NALKDAHSKRVELEA
Site 44Y436LARMLREYQELMSVK
Site 45S441REYQELMSVKLALDI
Site 46Y453LDIEIATYRKLLEGE
Site 47Y462KLLEGEEYRMSGECQ
Site 48S465EGEEYRMSGECQSAV
Site 49S487STSTGGISGGLGSGS
Site 50S494SGGLGSGSGFGLSSG
Site 51S499SGSGFGLSSGFGSGS
Site 52S500GSGFGLSSGFGSGSG
Site 53S504GLSSGFGSGSGSGFG
Site 54S506SSGFGSGSGSGFGFG
Site 55S508GFGSGSGSGFGFGGS
Site 56S515SGFGFGGSVSGSSSS
Site 57S517FGFGGSVSGSSSSKI
Site 58S519FGGSVSGSSSSKIIS
Site 59S520GGSVSGSSSSKIIST
Site 60S521GSVSGSSSSKIISTT
Site 61S522SVSGSSSSKIISTTT
Site 62S526SSSSKIISTTTLNKR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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