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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATF6
Full Name:
Cyclic AMP-dependent transcription factor ATF-6 alpha
Alias:
Activating transcription factor 6; Activating transcription factor 6 alpha; ATF6A; ATF6-alpha
Type:
Transcription factor
Mass (Da):
74580
Number AA:
UniProt ID:
P18850
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005789
GO:0016021
GO:0005635
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0046983
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006990
GO:0006457
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
G
T
M
E
S
P
F
S
P
G
L
F
H
R
L
Site 2
S29
R
L
D
E
D
W
D
S
A
L
F
A
E
L
G
Site 3
T41
E
L
G
Y
F
T
D
T
D
E
L
Q
L
E
A
Site 4
Y53
L
E
A
A
N
E
T
Y
E
N
N
F
D
N
L
Site 5
S94
K
A
E
P
Q
P
L
S
P
A
S
S
S
Y
S
Site 6
S97
P
Q
P
L
S
P
A
S
S
S
Y
S
V
S
S
Site 7
S98
Q
P
L
S
P
A
S
S
S
Y
S
V
S
S
P
Site 8
S99
P
L
S
P
A
S
S
S
Y
S
V
S
S
P
R
Site 9
Y100
L
S
P
A
S
S
S
Y
S
V
S
S
P
R
S
Site 10
S101
S
P
A
S
S
S
Y
S
V
S
S
P
R
S
V
Site 11
S103
A
S
S
S
Y
S
V
S
S
P
R
S
V
D
S
Site 12
S104
S
S
S
Y
S
V
S
S
P
R
S
V
D
S
Y
Site 13
S107
Y
S
V
S
S
P
R
S
V
D
S
Y
S
S
T
Site 14
S110
S
S
P
R
S
V
D
S
Y
S
S
T
Q
H
V
Site 15
Y111
S
P
R
S
V
D
S
Y
S
S
T
Q
H
V
P
Site 16
S112
P
R
S
V
D
S
Y
S
S
T
Q
H
V
P
E
Site 17
T114
S
V
D
S
Y
S
S
T
Q
H
V
P
E
E
L
Site 18
S124
V
P
E
E
L
D
L
S
S
S
S
Q
M
S
P
Site 19
S125
P
E
E
L
D
L
S
S
S
S
Q
M
S
P
L
Site 20
S126
E
E
L
D
L
S
S
S
S
Q
M
S
P
L
S
Site 21
S127
E
L
D
L
S
S
S
S
Q
M
S
P
L
S
L
Site 22
S130
L
S
S
S
S
Q
M
S
P
L
S
L
Y
G
E
Site 23
S133
S
S
Q
M
S
P
L
S
L
Y
G
E
N
S
N
Site 24
Y135
Q
M
S
P
L
S
L
Y
G
E
N
S
N
S
L
Site 25
S139
L
S
L
Y
G
E
N
S
N
S
L
S
S
A
E
Site 26
S141
L
Y
G
E
N
S
N
S
L
S
S
A
E
P
L
Site 27
S143
G
E
N
S
N
S
L
S
S
A
E
P
L
K
E
Site 28
T161
V
T
G
P
R
N
K
T
E
N
G
L
T
P
K
Site 29
T166
N
K
T
E
N
G
L
T
P
K
K
K
I
Q
V
Site 30
S178
I
Q
V
N
S
K
P
S
I
Q
P
K
P
L
L
Site 31
T192
L
L
P
A
A
P
K
T
Q
T
N
S
S
V
P
Site 32
T194
P
A
A
P
K
T
Q
T
N
S
S
V
P
A
K
Site 33
S197
P
K
T
Q
T
N
S
S
V
P
A
K
T
I
I
Site 34
S222
A
K
Q
Q
P
I
I
S
L
Q
P
A
P
T
K
Site 35
T232
P
A
P
T
K
G
Q
T
V
L
L
S
Q
P
T
Site 36
S280
V
P
A
P
S
A
N
S
P
V
N
G
K
L
S
Site 37
S287
S
P
V
N
G
K
L
S
V
T
K
P
V
L
Q
Site 38
T296
T
K
P
V
L
Q
S
T
M
R
N
V
G
S
D
Site 39
S302
S
T
M
R
N
V
G
S
D
I
A
V
L
R
R
Site 40
S319
R
M
I
K
N
R
E
S
A
C
Q
S
R
K
K
Site 41
S323
N
R
E
S
A
C
Q
S
R
K
K
K
K
E
Y
Site 42
Y330
S
R
K
K
K
K
E
Y
M
L
G
L
E
A
R
Site 43
S343
A
R
L
K
A
A
L
S
E
N
E
Q
L
K
K
Site 44
S364
R
Q
L
D
E
V
V
S
E
N
Q
R
L
K
V
Site 45
S373
N
Q
R
L
K
V
P
S
P
K
R
R
V
V
C
Site 46
S396
I
L
N
Y
G
P
M
S
M
L
E
Q
D
S
R
Site 47
S402
M
S
M
L
E
Q
D
S
R
R
M
N
P
S
V
Site 48
S408
D
S
R
R
M
N
P
S
V
S
P
A
N
Q
R
Site 49
S410
R
R
M
N
P
S
V
S
P
A
N
Q
R
R
H
Site 50
T429
S
A
K
E
A
Q
D
T
S
D
G
I
I
Q
K
Site 51
Y439
G
I
I
Q
K
N
S
Y
R
Y
D
H
S
V
S
Site 52
S444
N
S
Y
R
Y
D
H
S
V
S
N
D
K
A
L
Site 53
Y461
L
T
E
E
P
L
L
Y
I
P
P
P
P
C
Q
Site 54
S476
P
L
I
N
T
T
E
S
L
R
L
N
H
E
L
Site 55
T495
H
R
H
E
V
E
R
T
K
S
R
R
M
T
N
Site 56
S497
H
E
V
E
R
T
K
S
R
R
M
T
N
N
Q
Site 57
T501
R
T
K
S
R
R
M
T
N
N
Q
Q
K
T
R
Site 58
T507
M
T
N
N
Q
Q
K
T
R
I
L
Q
G
A
L
Site 59
S518
Q
G
A
L
E
Q
G
S
N
S
Q
L
M
A
V
Site 60
S520
A
L
E
Q
G
S
N
S
Q
L
M
A
V
Q
Y
Site 61
Y527
S
Q
L
M
A
V
Q
Y
T
E
T
T
S
S
I
Site 62
T528
Q
L
M
A
V
Q
Y
T
E
T
T
S
S
I
S
Site 63
S532
V
Q
Y
T
E
T
T
S
S
I
S
R
N
S
G
Site 64
S533
Q
Y
T
E
T
T
S
S
I
S
R
N
S
G
S
Site 65
S535
T
E
T
T
S
S
I
S
R
N
S
G
S
E
L
Site 66
S538
T
S
S
I
S
R
N
S
G
S
E
L
Q
V
Y
Site 67
S540
S
I
S
R
N
S
G
S
E
L
Q
V
Y
Y
A
Site 68
Y545
S
G
S
E
L
Q
V
Y
Y
A
S
P
R
S
Y
Site 69
Y546
G
S
E
L
Q
V
Y
Y
A
S
P
R
S
Y
Q
Site 70
S548
E
L
Q
V
Y
Y
A
S
P
R
S
Y
Q
D
F
Site 71
S551
V
Y
Y
A
S
P
R
S
Y
Q
D
F
F
E
A
Site 72
Y552
Y
Y
A
S
P
R
S
Y
Q
D
F
F
E
A
I
Site 73
T565
A
I
R
R
R
G
D
T
F
Y
V
V
S
F
R
Site 74
Y567
R
R
R
G
D
T
F
Y
V
V
S
F
R
R
D
Site 75
S570
G
D
T
F
Y
V
V
S
F
R
R
D
H
L
L
Site 76
T581
D
H
L
L
L
P
A
T
T
H
N
K
T
T
R
Site 77
T586
P
A
T
T
H
N
K
T
T
R
P
K
M
S
I
Site 78
Y610
N
V
I
N
G
Q
D
Y
E
V
M
M
Q
I
D
Site 79
S630
T
R
I
L
H
I
K
S
S
S
V
P
P
Y
L
Site 80
S631
R
I
L
H
I
K
S
S
S
V
P
P
Y
L
R
Site 81
S632
I
L
H
I
K
S
S
S
V
P
P
Y
L
R
D
Site 82
Y636
K
S
S
S
V
P
P
Y
L
R
D
Q
Q
R
N
Site 83
T645
R
D
Q
Q
R
N
Q
T
N
T
F
F
G
S
P
Site 84
T647
Q
Q
R
N
Q
T
N
T
F
F
G
S
P
P
A
Site 85
S651
Q
T
N
T
F
F
G
S
P
P
A
A
T
E
A
Site 86
S663
T
E
A
T
H
V
V
S
T
I
P
E
S
L
Q
Site 87
T664
E
A
T
H
V
V
S
T
I
P
E
S
L
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation