PhosphoNET

           
Protein Info 
   
Short Name:  HOXB8
Full Name:  Homeobox protein Hox-B8
Alias:  Homeobox B8; Homeobox Hox-B8; HOX2; Hox-2.4; HOX2D; Hox-2D; HXB8
Type:  Nucleus protein
Mass (Da):  27574
Number AA:  243
UniProt ID:  P17481
International Prot ID:  IPI00014536
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MSSYFVNSLFSKYKT
Site 2Y13VNSLFSKYKTGESLR
Site 3T15SLFSKYKTGESLRPN
Site 4S18SKYKTGESLRPNYYD
Site 5Y23GESLRPNYYDCGFAQ
Site 6Y24ESLRPNYYDCGFAQD
Site 7T37QDLGGRPTVVYGPSS
Site 8Y40GGRPTVVYGPSSGGS
Site 9S43PTVVYGPSSGGSFQH
Site 10S44TVVYGPSSGGSFQHP
Site 11S47YGPSSGGSFQHPSQI
Site 12Y58PSQIQEFYHGPSSLS
Site 13S63EFYHGPSSLSTAPYQ
Site 14S65YHGPSSLSTAPYQQN
Site 15T66HGPSSLSTAPYQQNP
Site 16Y69SSLSTAPYQQNPCAV
Site 17Y86HGDPGNFYGYDPLQR
Site 18S95YDPLQRQSLFGAQDP
Site 19S125LGEEAEGSEQSPSPT
Site 20S128EAEGSEQSPSPTQLF
Site 21S130EGSEQSPSPTQLFPW
Site 22T132SEQSPSPTQLFPWMR
Site 23T152GRRRGRQTYSRYQTL
Site 24Y153RRRGRQTYSRYQTLE
Site 25S154RRGRQTYSRYQTLEL
Site 26Y156GRQTYSRYQTLELEK
Site 27T158QTYSRYQTLELEKEF
Site 28Y170KEFLFNPYLTRKRRI
Site 29S180RKRRIEVSHALGLTE
Site 30T186VSHALGLTERQVKIW
Site 31S213NKDKFPSSKCEQEEL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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