KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
BPI
Full Name:
Bactericidal permeability-increasing protein
Alias:
CAP 57
Type:
Mass (Da):
53900
Number AA:
487
UniProt ID:
P17213
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y47
I
S
Q
K
G
L
D
Y
A
S
Q
Q
G
T
A
Site 2
S49
Q
K
G
L
D
Y
A
S
Q
Q
G
T
A
A
L
Site 3
Y68
K
R
I
K
I
P
D
Y
S
D
S
F
K
I
K
Site 4
S69
R
I
K
I
P
D
Y
S
D
S
F
K
I
K
H
Site 5
S71
K
I
P
D
Y
S
D
S
F
K
I
K
H
L
G
Site 6
Y82
K
H
L
G
K
G
H
Y
S
F
Y
S
M
D
I
Site 7
Y85
G
K
G
H
Y
S
F
Y
S
M
D
I
R
E
F
Site 8
S96
I
R
E
F
Q
L
P
S
S
Q
I
S
M
V
P
Site 9
S97
R
E
F
Q
L
P
S
S
Q
I
S
M
V
P
N
Site 10
S110
P
N
V
G
L
K
F
S
I
S
N
A
N
I
K
Site 11
S132
Q
K
R
F
L
K
M
S
G
N
F
D
L
S
I
Site 12
S152
S
A
D
L
K
L
G
S
N
P
T
S
G
K
P
Site 13
S156
K
L
G
S
N
P
T
S
G
K
P
T
I
T
C
Site 14
T160
N
P
T
S
G
K
P
T
I
T
C
S
S
C
S
Site 15
T162
T
S
G
K
P
T
I
T
C
S
S
C
S
S
H
Site 16
S164
G
K
P
T
I
T
C
S
S
C
S
S
H
I
N
Site 17
S165
K
P
T
I
T
C
S
S
C
S
S
H
I
N
S
Site 18
S172
S
C
S
S
H
I
N
S
V
H
V
H
I
S
K
Site 19
S178
N
S
V
H
V
H
I
S
K
S
K
V
G
W
L
Site 20
S195
L
F
H
K
K
I
E
S
A
L
R
N
K
M
N
Site 21
S203
A
L
R
N
K
M
N
S
Q
V
C
E
K
V
T
Site 22
T210
S
Q
V
C
E
K
V
T
N
S
V
S
S
E
L
Site 23
S212
V
C
E
K
V
T
N
S
V
S
S
E
L
Q
P
Site 24
S214
E
K
V
T
N
S
V
S
S
E
L
Q
P
Y
F
Site 25
T310
E
A
G
V
L
K
M
T
L
R
D
D
M
I
P
Site 26
T325
K
E
S
K
F
R
L
T
T
K
F
F
G
T
F
Site 27
T326
E
S
K
F
R
L
T
T
K
F
F
G
T
F
L
Site 28
S350
M
K
I
Q
I
H
V
S
A
S
T
P
P
H
L
Site 29
T353
Q
I
H
V
S
A
S
T
P
P
H
L
S
V
Q
Site 30
S358
A
S
T
P
P
H
L
S
V
Q
P
T
G
L
T
Site 31
T362
P
H
L
S
V
Q
P
T
G
L
T
F
Y
P
A
Site 32
S396
I
G
M
H
T
T
G
S
M
E
V
S
A
E
S
Site 33
S400
T
T
G
S
M
E
V
S
A
E
S
N
R
L
V
Site 34
S403
S
M
E
V
S
A
E
S
N
R
L
V
G
E
L
Site 35
T460
Q
K
G
F
P
L
P
T
P
A
R
V
Q
L
Y
Site 36
Y467
T
P
A
R
V
Q
L
Y
N
V
V
L
Q
P
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation