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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSPA6
Full Name:
Heat shock 70 kDa protein 6
Alias:
Heat shock 70 kDa B'; Heat shock 70kDa 6 (HSP70''; HSP70B'; HSP76
Type:
Uncharacterized protein
Mass (Da):
71028
Number AA:
643
UniProt ID:
P17066
International Prot ID:
IPI00339269
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
PhosphoSite+
KinaseNET
Biological Process:
GO:0006986
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
A
V
G
I
D
L
G
T
T
Y
S
C
V
G
V
Site 2
Y17
G
I
D
L
G
T
T
Y
S
C
V
G
V
F
Q
Site 3
T40
N
D
Q
G
N
R
T
T
P
S
Y
V
A
F
T
Site 4
S42
Q
G
N
R
T
T
P
S
Y
V
A
F
T
D
T
Site 5
Y43
G
N
R
T
T
P
S
Y
V
A
F
T
D
T
E
Site 6
T49
S
Y
V
A
F
T
D
T
E
R
L
V
G
D
A
Site 7
S59
L
V
G
D
A
A
K
S
Q
A
A
L
N
P
H
Site 8
T68
A
A
L
N
P
H
N
T
V
F
D
A
K
R
L
Site 9
T83
I
G
R
K
F
A
D
T
T
V
Q
S
D
M
K
Site 10
T84
G
R
K
F
A
D
T
T
V
Q
S
D
M
K
H
Site 11
S98
H
W
P
F
R
V
V
S
E
G
G
K
P
K
V
Site 12
Y109
K
P
K
V
R
V
C
Y
R
G
E
D
K
T
F
Site 13
T115
C
Y
R
G
E
D
K
T
F
Y
P
E
E
I
S
Site 14
Y117
R
G
E
D
K
T
F
Y
P
E
E
I
S
S
M
Site 15
S122
T
F
Y
P
E
E
I
S
S
M
V
L
S
K
M
Site 16
S123
F
Y
P
E
E
I
S
S
M
V
L
S
K
M
K
Site 17
S127
E
I
S
S
M
V
L
S
K
M
K
E
T
A
E
Site 18
Y151
A
V
I
T
V
P
A
Y
F
N
D
S
Q
R
Q
Site 19
S155
V
P
A
Y
F
N
D
S
Q
R
Q
A
T
K
D
Site 20
T160
N
D
S
Q
R
Q
A
T
K
D
A
G
A
I
A
Site 21
T179
L
R
I
I
N
E
P
T
A
A
A
I
A
Y
G
Site 22
S256
R
K
H
G
K
D
L
S
G
N
K
R
A
L
R
Site 23
T267
R
A
L
R
R
L
R
T
A
C
E
R
A
K
R
Site 24
T275
A
C
E
R
A
K
R
T
L
S
S
S
T
Q
A
Site 25
S277
E
R
A
K
R
T
L
S
S
S
T
Q
A
T
L
Site 26
S278
R
A
K
R
T
L
S
S
S
T
Q
A
T
L
E
Site 27
S279
A
K
R
T
L
S
S
S
T
Q
A
T
L
E
I
Site 28
Y296
L
F
E
G
V
D
F
Y
T
S
I
T
R
A
R
Site 29
S298
E
G
V
D
F
Y
T
S
I
T
R
A
R
F
E
Site 30
T300
V
D
F
Y
T
S
I
T
R
A
R
F
E
E
L
Site 31
S309
A
R
F
E
E
L
C
S
D
L
F
R
S
T
L
Site 32
S314
L
C
S
D
L
F
R
S
T
L
E
P
V
E
K
Site 33
T315
C
S
D
L
F
R
S
T
L
E
P
V
E
K
A
Site 34
S364
N
G
K
E
L
N
K
S
I
N
P
D
E
A
V
Site 35
T421
T
L
I
Q
R
N
A
T
I
P
T
K
Q
T
Q
Site 36
T429
I
P
T
K
Q
T
Q
T
F
T
T
Y
S
D
N
Site 37
Y433
Q
T
Q
T
F
T
T
Y
S
D
N
Q
P
G
V
Site 38
S434
T
Q
T
F
T
T
Y
S
D
N
Q
P
G
V
F
Site 39
Y445
P
G
V
F
I
Q
V
Y
E
G
E
R
A
M
T
Site 40
T452
Y
E
G
E
R
A
M
T
K
D
N
N
L
L
G
Site 41
S464
L
L
G
R
F
E
L
S
G
I
P
P
A
P
R
Site 42
T493
G
I
L
S
V
T
A
T
D
R
S
T
G
K
A
Site 43
T497
V
T
A
T
D
R
S
T
G
K
A
N
K
I
T
Site 44
T504
T
G
K
A
N
K
I
T
I
T
N
D
K
G
R
Site 45
S513
T
N
D
K
G
R
L
S
K
E
E
V
E
R
M
Site 46
Y527
M
V
H
E
A
E
Q
Y
K
A
E
D
E
A
Q
Site 47
S554
H
V
F
H
V
K
G
S
L
Q
E
E
S
L
R
Site 48
S559
K
G
S
L
Q
E
E
S
L
R
D
K
I
P
E
Site 49
Y594
Q
L
A
E
K
E
E
Y
E
H
Q
K
R
E
L
Site 50
S610
Q
I
C
R
P
I
F
S
R
L
Y
G
G
P
G
Site 51
Y613
R
P
I
F
S
R
L
Y
G
G
P
G
V
P
G
Site 52
S622
G
P
G
V
P
G
G
S
S
C
G
T
Q
A
R
Site 53
S623
P
G
V
P
G
G
S
S
C
G
T
Q
A
R
Q
Site 54
T626
P
G
G
S
S
C
G
T
Q
A
R
Q
G
D
P
Site 55
S634
Q
A
R
Q
G
D
P
S
T
G
P
I
I
E
E
Site 56
T635
A
R
Q
G
D
P
S
T
G
P
I
I
E
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation