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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TCF9
Full Name:
GC-rich sequence DNA-binding factor
Alias:
C2orf3; Chromosome 2 open reading frame 3; DNABF; GC bindng factor; GCF; TCF-9; Transcription factor 9
Type:
Mass (Da):
89385
Number AA:
781
UniProt ID:
P16383
International Prot ID:
IPI00418340
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
H
R
P
K
R
T
F
R
Q
R
A
A
D
Site 2
S16
F
R
Q
R
A
A
D
S
S
D
S
D
G
A
E
Site 3
S17
R
Q
R
A
A
D
S
S
D
S
D
G
A
E
E
Site 4
S19
R
A
A
D
S
S
D
S
D
G
A
E
E
S
P
Site 5
S25
D
S
D
G
A
E
E
S
P
A
E
P
G
A
P
Site 6
S40
R
E
L
P
V
P
G
S
A
E
E
E
P
P
S
Site 7
S47
S
A
E
E
E
P
P
S
G
G
G
R
A
Q
V
Site 8
S73
G
R
G
R
V
W
A
S
S
R
R
A
T
K
A
Site 9
S74
R
G
R
V
W
A
S
S
R
R
A
T
K
A
A
Site 10
T78
W
A
S
S
R
R
A
T
K
A
A
P
R
A
D
Site 11
S88
A
P
R
A
D
E
G
S
E
S
R
T
L
D
V
Site 12
S90
R
A
D
E
G
S
E
S
R
T
L
D
V
S
T
Site 13
T92
D
E
G
S
E
S
R
T
L
D
V
S
T
D
E
Site 14
S96
E
S
R
T
L
D
V
S
T
D
E
E
D
K
I
Site 15
T97
S
R
T
L
D
V
S
T
D
E
E
D
K
I
H
Site 16
S116
S
K
D
D
Q
G
L
S
S
D
S
S
S
S
L
Site 17
S117
K
D
D
Q
G
L
S
S
D
S
S
S
S
L
G
Site 18
S119
D
Q
G
L
S
S
D
S
S
S
S
L
G
E
K
Site 19
S120
Q
G
L
S
S
D
S
S
S
S
L
G
E
K
E
Site 20
S121
G
L
S
S
D
S
S
S
S
L
G
E
K
E
L
Site 21
S122
L
S
S
D
S
S
S
S
L
G
E
K
E
L
S
Site 22
S129
S
L
G
E
K
E
L
S
S
T
V
K
I
P
D
Site 23
S130
L
G
E
K
E
L
S
S
T
V
K
I
P
D
A
Site 24
T131
G
E
K
E
L
S
S
T
V
K
I
P
D
A
A
Site 25
Y156
L
A
R
A
Q
D
D
Y
I
S
L
D
V
Q
H
Site 26
S158
R
A
Q
D
D
Y
I
S
L
D
V
Q
H
T
S
Site 27
T164
I
S
L
D
V
Q
H
T
S
S
I
S
G
M
K
Site 28
S165
S
L
D
V
Q
H
T
S
S
I
S
G
M
K
R
Site 29
S166
L
D
V
Q
H
T
S
S
I
S
G
M
K
R
E
Site 30
S174
I
S
G
M
K
R
E
S
E
D
D
P
E
S
E
Site 31
S180
E
S
E
D
D
P
E
S
E
P
D
D
H
E
K
Site 32
T192
H
E
K
R
I
P
F
T
L
R
P
Q
T
L
R
Site 33
T197
P
F
T
L
R
P
Q
T
L
R
Q
R
M
A
E
Site 34
S206
R
Q
R
M
A
E
E
S
I
S
R
N
E
E
T
Site 35
S208
R
M
A
E
E
S
I
S
R
N
E
E
T
S
E
Site 36
T213
S
I
S
R
N
E
E
T
S
E
E
S
Q
E
D
Site 37
S214
I
S
R
N
E
E
T
S
E
E
S
Q
E
D
E
Site 38
S217
N
E
E
T
S
E
E
S
Q
E
D
E
K
Q
D
Site 39
T225
Q
E
D
E
K
Q
D
T
W
E
Q
Q
Q
M
R
Site 40
S246
E
E
R
D
I
D
L
S
C
G
N
G
S
S
K
Site 41
S251
D
L
S
C
G
N
G
S
S
K
V
K
K
F
D
Site 42
S252
L
S
C
G
N
G
S
S
K
V
K
K
F
D
T
Site 43
T259
S
K
V
K
K
F
D
T
S
I
S
F
P
P
V
Site 44
S260
K
V
K
K
F
D
T
S
I
S
F
P
P
V
N
Site 45
S262
K
K
F
D
T
S
I
S
F
P
P
V
N
L
E
Site 46
T280
K
Q
L
N
T
R
L
T
L
L
Q
E
T
H
R
Site 47
T285
R
L
T
L
L
Q
E
T
H
R
S
H
L
R
E
Site 48
S288
L
L
Q
E
T
H
R
S
H
L
R
E
Y
E
K
Site 49
Y293
H
R
S
H
L
R
E
Y
E
K
Y
V
Q
D
V
Site 50
Y296
H
L
R
E
Y
E
K
Y
V
Q
D
V
K
S
S
Site 51
S302
K
Y
V
Q
D
V
K
S
S
K
S
T
I
Q
N
Site 52
S305
Q
D
V
K
S
S
K
S
T
I
Q
N
L
E
S
Site 53
T306
D
V
K
S
S
K
S
T
I
Q
N
L
E
S
S
Site 54
Y323
Q
A
L
N
C
K
F
Y
K
S
M
K
I
Y
V
Site 55
S350
N
I
Q
E
I
E
S
S
M
H
A
L
L
L
K
Site 56
T361
L
L
L
K
Q
A
M
T
F
M
K
R
R
Q
D
Site 57
T375
D
E
L
K
H
E
S
T
Y
L
Q
Q
L
S
R
Site 58
Y376
E
L
K
H
E
S
T
Y
L
Q
Q
L
S
R
K
Site 59
S381
S
T
Y
L
Q
Q
L
S
R
K
D
E
T
S
T
Site 60
S387
L
S
R
K
D
E
T
S
T
S
G
N
F
S
V
Site 61
S389
R
K
D
E
T
S
T
S
G
N
F
S
V
D
E
Site 62
S393
T
S
T
S
G
N
F
S
V
D
E
K
T
Q
W
Site 63
T398
N
F
S
V
D
E
K
T
Q
W
I
L
E
E
I
Site 64
S407
W
I
L
E
E
I
E
S
R
R
T
K
R
R
Q
Site 65
T410
E
E
I
E
S
R
R
T
K
R
R
Q
A
R
V
Site 66
S419
R
R
Q
A
R
V
L
S
G
N
C
N
H
Q
E
Site 67
T428
N
C
N
H
Q
E
G
T
S
S
D
D
E
L
P
Site 68
S429
C
N
H
Q
E
G
T
S
S
D
D
E
L
P
S
Site 69
S430
N
H
Q
E
G
T
S
S
D
D
E
L
P
S
A
Site 70
S436
S
S
D
D
E
L
P
S
A
E
M
I
D
F
Q
Site 71
S445
E
M
I
D
F
Q
K
S
Q
G
D
I
L
Q
K
Site 72
Y485
R
E
K
F
P
D
S
Y
Y
E
A
F
I
S
L
Site 73
Y486
E
K
F
P
D
S
Y
Y
E
A
F
I
S
L
C
Site 74
S534
S
V
E
E
F
M
D
S
S
V
E
D
S
K
K
Site 75
S535
V
E
E
F
M
D
S
S
V
E
D
S
K
K
E
Site 76
S539
M
D
S
S
V
E
D
S
K
K
E
S
S
S
D
Site 77
S543
V
E
D
S
K
K
E
S
S
S
D
K
K
V
L
Site 78
S544
E
D
S
K
K
E
S
S
S
D
K
K
V
L
S
Site 79
S545
D
S
K
K
E
S
S
S
D
K
K
V
L
S
A
Site 80
S551
S
S
D
K
K
V
L
S
A
I
I
N
K
T
I
Site 81
S574
E
F
L
W
D
P
L
S
T
S
Q
T
T
S
L
Site 82
S576
L
W
D
P
L
S
T
S
Q
T
T
S
L
I
T
Site 83
T578
D
P
L
S
T
S
Q
T
T
S
L
I
T
H
C
Site 84
S580
L
S
T
S
Q
T
T
S
L
I
T
H
C
R
V
Site 85
S593
R
V
I
L
E
E
H
S
T
C
E
N
E
V
S
Site 86
T594
V
I
L
E
E
H
S
T
C
E
N
E
V
S
K
Site 87
S600
S
T
C
E
N
E
V
S
K
S
R
Q
D
L
L
Site 88
S602
C
E
N
E
V
S
K
S
R
Q
D
L
L
K
S
Site 89
S609
S
R
Q
D
L
L
K
S
I
V
S
R
M
K
K
Site 90
Y627
D
D
V
F
I
P
L
Y
P
K
S
A
V
E
N
Site 91
S630
F
I
P
L
Y
P
K
S
A
V
E
N
K
T
S
Site 92
T636
K
S
A
V
E
N
K
T
S
P
H
S
K
F
Q
Site 93
S637
S
A
V
E
N
K
T
S
P
H
S
K
F
Q
E
Site 94
S640
E
N
K
T
S
P
H
S
K
F
Q
E
R
Q
F
Site 95
T668
N
G
L
L
T
D
D
T
L
Q
E
L
G
L
G
Site 96
Y681
L
G
K
L
L
N
R
Y
L
I
I
A
L
L
N
Site 97
S714
P
E
K
W
F
E
N
S
A
M
R
T
S
I
P
Site 98
T718
F
E
N
S
A
M
R
T
S
I
P
Q
L
E
N
Site 99
S719
E
N
S
A
M
R
T
S
I
P
Q
L
E
N
F
Site 100
S733
F
I
Q
F
L
L
Q
S
A
H
K
L
S
R
S
Site 101
S738
L
Q
S
A
H
K
L
S
R
S
E
F
R
D
E
Site 102
S740
S
A
H
K
L
S
R
S
E
F
R
D
E
V
E
Site 103
S764
K
A
L
N
Q
A
E
S
F
I
G
E
H
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation