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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLB1
Full Name:
Beta-galactosidase
Alias:
Acid beta-galactosidase; Beta-galactosidase; BGAL; EBP; Elastin receptor 1; ELNR1; Galactosidase, beta 1; Lactase
Type:
Glycan Metabolism - glycosaminoglycan degradation; EC 3.2.1.23; Hydrolase; Carbohydrate Metabolism - galactose; Lipid Metabolism - sphingolipid; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Glycan Metabolism - other glycan degradation
Mass (Da):
76075
Number AA:
677
UniProt ID:
P16278
International Prot ID:
IPI00441344
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005764
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0004565
GO:0043169
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0005975
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
V
L
L
L
L
G
P
T
R
G
L
R
N
A
T
Site 2
T28
T
R
G
L
R
N
A
T
Q
R
M
F
E
I
D
Site 3
Y36
Q
R
M
F
E
I
D
Y
S
R
D
S
F
L
K
Site 4
S37
R
M
F
E
I
D
Y
S
R
D
S
F
L
K
D
Site 5
S40
E
I
D
Y
S
R
D
S
F
L
K
D
G
Q
P
Site 6
Y50
K
D
G
Q
P
F
R
Y
I
S
G
S
I
H
Y
Site 7
S52
G
Q
P
F
R
Y
I
S
G
S
I
H
Y
S
R
Site 8
S54
P
F
R
Y
I
S
G
S
I
H
Y
S
R
V
P
Site 9
Y57
Y
I
S
G
S
I
H
Y
S
R
V
P
R
F
Y
Site 10
Y64
Y
S
R
V
P
R
F
Y
W
K
D
R
L
L
K
Site 11
Y83
G
L
N
A
I
Q
T
Y
V
P
W
N
F
H
E
Site 12
Y96
H
E
P
W
P
G
Q
Y
Q
F
S
E
D
H
D
Site 13
Y106
S
E
D
H
D
V
E
Y
F
L
R
L
A
H
E
Site 14
S144
A
W
L
L
E
K
E
S
I
L
L
R
S
S
D
Site 15
S150
E
S
I
L
L
R
S
S
D
P
D
Y
L
A
A
Site 16
Y154
L
R
S
S
D
P
D
Y
L
A
A
V
D
K
W
Site 17
Y174
P
K
M
K
P
L
L
Y
Q
N
G
G
P
V
I
Site 18
T182
Q
N
G
G
P
V
I
T
V
Q
V
E
N
E
Y
Site 19
Y189
T
V
Q
V
E
N
E
Y
G
S
Y
F
A
C
D
Site 20
Y192
V
E
N
E
Y
G
S
Y
F
A
C
D
F
D
Y
Site 21
Y199
Y
F
A
C
D
F
D
Y
L
R
F
L
Q
K
R
Site 22
T226
T
T
D
G
A
H
K
T
F
L
K
C
G
A
L
Site 23
T239
A
L
Q
G
L
Y
T
T
V
D
F
G
T
G
S
Site 24
T244
Y
T
T
V
D
F
G
T
G
S
N
I
T
D
A
Site 25
T249
F
G
T
G
S
N
I
T
D
A
F
L
S
Q
R
Site 26
S254
N
I
T
D
A
F
L
S
Q
R
K
C
E
P
K
Site 27
S267
P
K
G
P
L
I
N
S
E
F
Y
T
G
W
L
Site 28
T286
Q
P
H
S
T
I
K
T
E
A
V
A
S
S
L
Site 29
Y294
E
A
V
A
S
S
L
Y
D
I
L
A
R
G
A
Site 30
Y316
I
G
G
T
N
F
A
Y
W
N
G
A
N
S
P
Site 31
S322
A
Y
W
N
G
A
N
S
P
Y
A
A
Q
P
T
Site 32
S330
P
Y
A
A
Q
P
T
S
Y
D
Y
D
A
P
L
Site 33
Y333
A
Q
P
T
S
Y
D
Y
D
A
P
L
S
E
A
Site 34
S338
Y
D
Y
D
A
P
L
S
E
A
G
D
L
T
E
Site 35
T344
L
S
E
A
G
D
L
T
E
K
Y
F
A
L
R
Site 36
S368
P
E
G
P
I
P
P
S
T
P
K
F
A
Y
G
Site 37
T369
E
G
P
I
P
P
S
T
P
K
F
A
Y
G
K
Site 38
Y374
P
S
T
P
K
F
A
Y
G
K
V
T
L
E
K
Site 39
T405
I
K
S
L
Y
P
L
T
F
I
Q
V
K
Q
H
Site 40
Y418
Q
H
Y
G
F
V
L
Y
R
T
T
L
P
Q
D
Site 41
T421
G
F
V
L
Y
R
T
T
L
P
Q
D
C
S
N
Site 42
S427
T
T
L
P
Q
D
C
S
N
P
A
P
L
S
S
Site 43
S433
C
S
N
P
A
P
L
S
S
P
L
N
G
V
H
Site 44
S434
S
N
P
A
P
L
S
S
P
L
N
G
V
H
D
Site 45
Y444
N
G
V
H
D
R
A
Y
V
A
V
D
G
I
P
Site 46
T462
L
E
R
N
N
V
I
T
L
N
I
T
G
K
A
Site 47
Y485
E
N
M
G
R
V
N
Y
G
A
Y
I
N
D
F
Site 48
Y488
G
R
V
N
Y
G
A
Y
I
N
D
F
K
G
L
Site 49
T510
S
N
I
L
T
D
W
T
I
F
P
L
D
T
E
Site 50
T516
W
T
I
F
P
L
D
T
E
D
A
V
R
S
H
Site 51
S522
D
T
E
D
A
V
R
S
H
L
G
G
W
G
H
Site 52
Y546
W
A
H
N
S
S
N
Y
T
L
P
A
F
Y
M
Site 53
T547
A
H
N
S
S
N
Y
T
L
P
A
F
Y
M
G
Site 54
S560
M
G
N
F
S
I
P
S
G
I
P
D
L
P
Q
Site 55
Y591
N
G
F
N
L
G
R
Y
W
P
A
R
G
P
Q
Site 56
T600
P
A
R
G
P
Q
L
T
L
F
V
P
Q
H
I
Site 57
S627
E
L
E
W
A
P
C
S
S
D
D
P
E
L
C
Site 58
S628
L
E
W
A
P
C
S
S
D
D
P
E
L
C
A
Site 59
S646
V
D
R
P
V
I
G
S
S
V
T
Y
D
H
P
Site 60
Y650
V
I
G
S
S
V
T
Y
D
H
P
S
K
P
V
Site 61
S654
S
V
T
Y
D
H
P
S
K
P
V
E
K
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation