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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PNLIP
Full Name:
Pancreatic triacylglycerol lipase
Alias:
Type:
Mass (Da):
51157
Number AA:
465
UniProt ID:
P16233
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
Y
E
R
L
G
C
F
S
D
D
S
P
W
S
G
Site 2
S31
L
G
C
F
S
D
D
S
P
W
S
G
I
T
E
Site 3
S34
F
S
D
D
S
P
W
S
G
I
T
E
R
P
L
Site 4
T37
D
S
P
W
S
G
I
T
E
R
P
L
H
I
L
Site 5
S47
P
L
H
I
L
P
W
S
P
K
D
V
N
T
R
Site 6
Y58
V
N
T
R
F
L
L
Y
T
N
E
N
P
N
N
Site 7
T59
N
T
R
F
L
L
Y
T
N
E
N
P
N
N
F
Site 8
S73
F
Q
E
V
A
A
D
S
S
S
I
S
G
S
N
Site 9
S74
Q
E
V
A
A
D
S
S
S
I
S
G
S
N
F
Site 10
S75
E
V
A
A
D
S
S
S
I
S
G
S
N
F
K
Site 11
S77
A
A
D
S
S
S
I
S
G
S
N
F
K
T
N
Site 12
S79
D
S
S
S
I
S
G
S
N
F
K
T
N
R
K
Site 13
T83
I
S
G
S
N
F
K
T
N
R
K
T
R
F
I
Site 14
Y131
K
G
G
S
R
T
G
Y
T
Q
A
S
Q
N
I
Site 15
T132
G
G
S
R
T
G
Y
T
Q
A
S
Q
N
I
R
Site 16
S135
R
T
G
Y
T
Q
A
S
Q
N
I
R
I
V
G
Site 17
S161
S
A
F
G
Y
S
P
S
N
V
H
V
I
G
H
Site 18
T182
A
G
E
A
G
R
R
T
N
G
T
I
G
R
I
Site 19
T185
A
G
R
R
T
N
G
T
I
G
R
I
T
G
L
Site 20
T190
N
G
T
I
G
R
I
T
G
L
D
P
A
E
P
Site 21
T202
A
E
P
C
F
Q
G
T
P
E
L
V
R
L
D
Site 22
S211
E
L
V
R
L
D
P
S
D
A
K
F
V
D
V
Site 23
S260
G
C
K
K
N
I
L
S
Q
I
V
D
I
D
G
Site 24
Y284
A
C
N
H
L
R
S
Y
K
Y
Y
T
D
S
I
Site 25
Y286
N
H
L
R
S
Y
K
Y
Y
T
D
S
I
V
N
Site 26
Y287
H
L
R
S
Y
K
Y
Y
T
D
S
I
V
N
P
Site 27
Y327
G
C
P
Q
M
G
H
Y
A
D
R
Y
P
G
K
Site 28
Y331
M
G
H
Y
A
D
R
Y
P
G
K
T
N
D
V
Site 29
T335
A
D
R
Y
P
G
K
T
N
D
V
G
Q
K
F
Site 30
Y343
N
D
V
G
Q
K
F
Y
L
D
T
G
D
A
S
Site 31
T346
G
Q
K
F
Y
L
D
T
G
D
A
S
N
F
A
Site 32
Y357
S
N
F
A
R
W
R
Y
K
V
S
V
T
L
S
Site 33
S360
A
R
W
R
Y
K
V
S
V
T
L
S
G
K
K
Site 34
S364
Y
K
V
S
V
T
L
S
G
K
K
V
T
G
H
Site 35
S383
L
F
G
N
K
G
N
S
K
Q
Y
E
I
F
K
Site 36
Y386
N
K
G
N
S
K
Q
Y
E
I
F
K
G
T
L
Site 37
T392
Q
Y
E
I
F
K
G
T
L
K
P
D
S
T
H
Site 38
S397
K
G
T
L
K
P
D
S
T
H
S
N
E
F
D
Site 39
T398
G
T
L
K
P
D
S
T
H
S
N
E
F
D
S
Site 40
S400
L
K
P
D
S
T
H
S
N
E
F
D
S
D
V
Site 41
S405
T
H
S
N
E
F
D
S
D
V
D
V
G
D
L
Site 42
Y420
Q
M
V
K
F
I
W
Y
N
N
V
I
N
P
T
Site 43
T427
Y
N
N
V
I
N
P
T
L
P
R
V
G
A
S
Site 44
S450
G
K
Q
F
N
F
C
S
P
E
T
V
R
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation