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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RAG1
Full Name:
V(D)J recombination-activating protein 1
Alias:
RING finger protein 74
Type:
Mass (Da):
119116
Number AA:
1043
UniProt ID:
P15918
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
F
P
P
T
L
G
L
S
S
A
P
D
E
I
Q
Site 2
S13
P
P
T
L
G
L
S
S
A
P
D
E
I
Q
H
Site 3
S37
F
K
L
F
R
V
R
S
F
E
K
T
P
E
E
Site 4
T41
R
V
R
S
F
E
K
T
P
E
E
A
Q
K
E
Site 5
S52
A
Q
K
E
K
K
D
S
F
E
G
K
P
S
L
Site 6
S58
D
S
F
E
G
K
P
S
L
E
Q
S
P
A
V
Site 7
S62
G
K
P
S
L
E
Q
S
P
A
V
L
D
K
A
Site 8
Y127
A
D
E
H
N
R
R
Y
P
V
H
G
P
V
D
Site 9
T137
H
G
P
V
D
G
K
T
L
G
L
L
R
K
K
Site 10
T149
R
K
K
E
K
R
A
T
S
W
P
D
L
I
A
Site 11
S150
K
K
E
K
R
A
T
S
W
P
D
L
I
A
K
Site 12
S169
D
V
K
A
D
V
D
S
I
H
P
T
E
F
C
Site 13
S188
S
I
M
H
R
K
F
S
S
A
P
C
E
V
Y
Site 14
Y195
S
S
A
P
C
E
V
Y
F
P
R
N
V
T
M
Site 15
T216
P
S
C
D
I
C
N
T
A
R
R
G
L
K
R
Site 16
S225
R
R
G
L
K
R
K
S
L
Q
P
N
L
Q
L
Site 17
S233
L
Q
P
N
L
Q
L
S
K
K
L
K
T
V
L
Site 18
T238
Q
L
S
K
K
L
K
T
V
L
D
Q
A
R
Q
Site 19
S258
R
R
A
Q
A
R
I
S
S
K
D
V
M
K
K
Site 20
S259
R
A
Q
A
R
I
S
S
K
D
V
M
K
K
I
Site 21
S270
M
K
K
I
A
N
C
S
K
I
H
L
S
T
K
Site 22
Y333
S
Y
C
P
S
C
R
Y
P
C
F
P
T
D
L
Site 23
T338
C
R
Y
P
C
F
P
T
D
L
E
S
P
V
K
Site 24
S342
C
F
P
T
D
L
E
S
P
V
K
S
F
L
S
Site 25
S346
D
L
E
S
P
V
K
S
F
L
S
V
L
N
S
Site 26
Y372
E
E
V
S
L
E
K
Y
N
H
H
I
S
S
H
Site 27
S377
E
K
Y
N
H
H
I
S
S
H
K
E
S
K
E
Site 28
S378
K
Y
N
H
H
I
S
S
H
K
E
S
K
E
I
Site 29
S401
R
P
R
Q
H
L
L
S
L
T
R
R
A
Q
K
Site 30
T403
R
Q
H
L
L
S
L
T
R
R
A
Q
K
H
R
Site 31
Y484
T
F
L
S
C
S
Q
Y
H
K
M
Y
R
T
V
Site 32
T490
Q
Y
H
K
M
Y
R
T
V
K
A
I
T
G
R
Site 33
Y517
E
K
V
L
L
P
G
Y
H
H
F
E
W
Q
P
Site 34
S530
Q
P
P
L
K
N
V
S
S
S
T
D
V
G
I
Site 35
S532
P
L
K
N
V
S
S
S
T
D
V
G
I
I
D
Site 36
S545
I
D
G
L
S
G
L
S
S
S
V
D
D
Y
P
Site 37
S546
D
G
L
S
G
L
S
S
S
V
D
D
Y
P
V
Site 38
S547
G
L
S
G
L
S
S
S
V
D
D
Y
P
V
D
Site 39
Y551
L
S
S
S
V
D
D
Y
P
V
D
T
I
A
K
Site 40
T555
V
D
D
Y
P
V
D
T
I
A
K
R
F
R
Y
Site 41
Y562
T
I
A
K
R
F
R
Y
D
S
A
L
V
S
A
Site 42
S568
R
Y
D
S
A
L
V
S
A
L
M
D
M
E
E
Site 43
S583
D
I
L
E
G
M
R
S
Q
D
L
D
D
Y
L
Site 44
Y589
R
S
Q
D
L
D
D
Y
L
N
G
P
F
T
V
Site 45
S609
C
D
G
M
G
D
V
S
E
K
H
G
S
G
P
Site 46
S614
D
V
S
E
K
H
G
S
G
P
V
V
P
E
K
Site 47
T633
S
F
T
I
M
K
I
T
I
A
H
S
S
Q
N
Site 48
S638
K
I
T
I
A
H
S
S
Q
N
V
K
V
F
E
Site 49
S651
F
E
E
A
K
P
N
S
E
L
C
C
K
P
L
Site 50
S666
C
L
M
L
A
D
E
S
D
H
E
T
L
T
A
Site 51
T670
A
D
E
S
D
H
E
T
L
T
A
I
L
S
P
Site 52
S687
A
E
R
E
A
M
K
S
S
E
L
M
L
E
L
Site 53
T708
F
K
F
I
F
R
G
T
G
Y
D
E
K
L
V
Site 54
S741
D
A
T
R
L
E
A
S
Q
N
L
V
F
H
S
Site 55
S748
S
Q
N
L
V
F
H
S
I
T
R
S
H
A
E
Site 56
S752
V
F
H
S
I
T
R
S
H
A
E
N
L
E
R
Site 57
Y760
H
A
E
N
L
E
R
Y
E
V
W
R
S
N
P
Site 58
S771
R
S
N
P
Y
H
E
S
V
E
E
L
R
D
R
Site 59
S783
R
D
R
V
K
G
V
S
A
K
P
F
I
E
T
Site 60
Y819
Q
L
E
I
G
E
V
Y
K
N
P
N
A
S
K
Site 61
T865
R
K
L
M
T
K
E
T
V
D
A
V
C
E
L
Site 62
S875
A
V
C
E
L
I
P
S
E
E
R
H
E
A
L
Site 63
Y889
L
R
E
L
M
D
L
Y
L
K
M
K
P
V
W
Site 64
S908
P
A
K
E
C
P
E
S
L
C
Q
Y
S
F
N
Site 65
Y912
C
P
E
S
L
C
Q
Y
S
F
N
S
Q
R
F
Site 66
S913
P
E
S
L
C
Q
Y
S
F
N
S
Q
R
F
A
Site 67
S916
L
C
Q
Y
S
F
N
S
Q
R
F
A
E
L
L
Site 68
S924
Q
R
F
A
E
L
L
S
T
K
F
K
Y
R
Y
Site 69
T925
R
F
A
E
L
L
S
T
K
F
K
Y
R
Y
E
Site 70
Y929
L
L
S
T
K
F
K
Y
R
Y
E
G
K
I
T
Site 71
Y931
S
T
K
F
K
Y
R
Y
E
G
K
I
T
N
Y
Site 72
Y938
Y
E
G
K
I
T
N
Y
F
H
K
T
L
A
H
Site 73
S955
E
I
I
E
R
D
G
S
I
G
A
W
A
S
E
Site 74
S961
G
S
I
G
A
W
A
S
E
G
N
E
S
G
N
Site 75
S966
W
A
S
E
G
N
E
S
G
N
K
L
F
R
R
Site 76
Y985
N
A
R
Q
S
K
C
Y
E
M
E
D
V
L
K
Site 77
Y997
V
L
K
H
H
W
L
Y
T
S
K
Y
L
Q
K
Site 78
S1034
D
P
L
G
I
E
D
S
L
E
S
Q
D
S
M
Site 79
S1037
G
I
E
D
S
L
E
S
Q
D
S
M
E
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation