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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHN1
Full Name:
N-chimaerin
Alias:
A-chimaerin;Alpha-chimerin;N-chimerin;Rho GTPase-activating protein 2
Type:
Mass (Da):
53172
Number AA:
459
UniProt ID:
P15882
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
L
T
L
F
D
T
D
E
Y
R
P
P
V
Site 2
Y11
T
L
F
D
T
D
E
Y
R
P
P
V
W
K
S
Site 3
Y19
R
P
P
V
W
K
S
Y
L
Y
Q
L
Q
Q
E
Site 4
Y21
P
V
W
K
S
Y
L
Y
Q
L
Q
Q
E
A
P
Site 5
T34
A
P
H
P
R
R
I
T
C
T
C
E
V
E
N
Site 6
T36
H
P
R
R
I
T
C
T
C
E
V
E
N
R
P
Site 7
Y45
E
V
E
N
R
P
K
Y
Y
G
R
E
F
H
G
Site 8
Y46
V
E
N
R
P
K
Y
Y
G
R
E
F
H
G
M
Site 9
Y70
L
I
V
A
E
G
S
Y
L
I
R
E
S
Q
R
Site 10
S75
G
S
Y
L
I
R
E
S
Q
R
Q
P
G
T
Y
Site 11
T81
E
S
Q
R
Q
P
G
T
Y
T
L
A
L
R
F
Site 12
Y82
S
Q
R
Q
P
G
T
Y
T
L
A
L
R
F
G
Site 13
T83
Q
R
Q
P
G
T
Y
T
L
A
L
R
F
G
S
Site 14
S90
T
L
A
L
R
F
G
S
Q
T
R
N
F
R
L
Site 15
T92
A
L
R
F
G
S
Q
T
R
N
F
R
L
Y
Y
Site 16
Y98
Q
T
R
N
F
R
L
Y
Y
D
G
K
H
F
V
Site 17
Y99
T
R
N
F
R
L
Y
Y
D
G
K
H
F
V
G
Site 18
S112
V
G
E
K
R
F
E
S
I
H
D
L
V
T
D
Site 19
T138
A
E
Y
I
A
K
M
T
I
N
P
I
Y
E
H
Site 20
Y143
K
M
T
I
N
P
I
Y
E
H
V
G
Y
T
T
Site 21
Y148
P
I
Y
E
H
V
G
Y
T
T
L
N
R
E
P
Site 22
T149
I
Y
E
H
V
G
Y
T
T
L
N
R
E
P
A
Site 23
T150
Y
E
H
V
G
Y
T
T
L
N
R
E
P
A
Y
Site 24
Y157
T
L
N
R
E
P
A
Y
K
K
H
M
P
V
L
Site 25
S173
E
T
H
D
E
R
D
S
T
G
Q
D
G
V
S
Site 26
T174
T
H
D
E
R
D
S
T
G
Q
D
G
V
S
E
Site 27
S180
S
T
G
Q
D
G
V
S
E
K
R
L
T
S
L
Site 28
T185
G
V
S
E
K
R
L
T
S
L
V
R
R
A
T
Site 29
S186
V
S
E
K
R
L
T
S
L
V
R
R
A
T
L
Site 30
T192
T
S
L
V
R
R
A
T
L
K
E
N
E
Q
I
Site 31
Y202
E
N
E
Q
I
P
K
Y
E
K
I
H
N
F
K
Site 32
Y266
L
K
H
V
K
K
V
Y
S
C
D
L
T
T
L
Site 33
T279
T
L
V
K
A
H
T
T
K
R
P
M
V
V
D
Site 34
Y303
G
L
N
S
E
G
L
Y
R
V
S
G
F
S
D
Site 35
S306
S
E
G
L
Y
R
V
S
G
F
S
D
L
I
E
Site 36
S309
L
Y
R
V
S
G
F
S
D
L
I
E
D
V
K
Site 37
S329
D
G
E
K
A
D
I
S
V
N
M
Y
E
D
I
Site 38
T340
Y
E
D
I
N
I
I
T
G
A
L
K
L
Y
F
Site 39
Y357
L
P
I
P
L
I
T
Y
D
A
Y
P
K
F
I
Site 40
Y360
P
L
I
T
Y
D
A
Y
P
K
F
I
E
S
A
Site 41
T378
D
P
D
E
Q
L
E
T
L
H
E
A
L
K
L
Site 42
T393
L
P
P
A
H
C
E
T
L
R
Y
L
M
A
H
Site 43
Y396
A
H
C
E
T
L
R
Y
L
M
A
H
L
K
R
Site 44
T405
M
A
H
L
K
R
V
T
L
H
E
K
E
N
L
Site 45
S429
F
G
P
T
L
M
R
S
P
E
L
D
A
M
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation