KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CPB1
Full Name:
Carboxypeptidase B
Alias:
Pancreas-specific protein
Type:
Mass (Da):
47368
Number AA:
417
UniProt ID:
P15086
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T47
I
I
R
E
L
A
S
T
T
Q
I
D
F
W
K
Site 2
T59
F
W
K
P
D
S
V
T
Q
I
K
P
H
S
T
Site 3
S65
V
T
Q
I
K
P
H
S
T
V
D
F
R
V
K
Site 4
T78
V
K
A
E
D
T
V
T
V
E
N
V
L
K
Q
Site 5
T112
F
D
S
R
V
R
A
T
G
H
S
Y
E
K
Y
Site 6
Y119
T
G
H
S
Y
E
K
Y
N
K
W
E
T
I
E
Site 7
T134
A
W
T
Q
Q
V
A
T
E
N
P
A
L
I
S
Site 8
T148
S
R
S
V
I
G
T
T
F
E
G
R
A
I
Y
Site 9
T196
F
V
R
E
A
V
R
T
Y
G
R
E
I
Q
V
Site 10
Y197
V
R
E
A
V
R
T
Y
G
R
E
I
Q
V
T
Site 11
T204
Y
G
R
E
I
Q
V
T
E
L
L
D
K
L
D
Site 12
Y223
P
V
L
N
I
D
G
Y
I
Y
T
W
T
K
S
Site 13
Y225
L
N
I
D
G
Y
I
Y
T
W
T
K
S
R
F
Site 14
T236
K
S
R
F
W
R
K
T
R
S
T
H
T
G
S
Site 15
S238
R
F
W
R
K
T
R
S
T
H
T
G
S
S
C
Site 16
T239
F
W
R
K
T
R
S
T
H
T
G
S
S
C
I
Site 17
S243
T
R
S
T
H
T
G
S
S
C
I
G
T
D
P
Site 18
S244
R
S
T
H
T
G
S
S
C
I
G
T
D
P
N
Site 19
T248
T
G
S
S
C
I
G
T
D
P
N
R
N
F
D
Site 20
T271
S
R
N
P
C
D
E
T
Y
C
G
P
A
A
E
Site 21
Y272
R
N
P
C
D
E
T
Y
C
G
P
A
A
E
S
Site 22
S295
D
F
I
R
N
K
L
S
S
I
K
A
Y
L
T
Site 23
Y300
K
L
S
S
I
K
A
Y
L
T
I
H
S
Y
S
Site 24
T302
S
S
I
K
A
Y
L
T
I
H
S
Y
S
Q
M
Site 25
Y312
S
Y
S
Q
M
M
I
Y
P
Y
S
Y
A
Y
K
Site 26
S340
A
T
V
K
E
L
A
S
L
H
G
T
K
Y
T
Site 27
T344
E
L
A
S
L
H
G
T
K
Y
T
Y
G
P
G
Site 28
Y346
A
S
L
H
G
T
K
Y
T
Y
G
P
G
A
T
Site 29
T347
S
L
H
G
T
K
Y
T
Y
G
P
G
A
T
T
Site 30
T354
T
Y
G
P
G
A
T
T
I
Y
P
A
A
G
G
Site 31
Y356
G
P
G
A
T
T
I
Y
P
A
A
G
G
S
D
Site 32
Y367
G
G
S
D
D
W
A
Y
D
Q
G
I
R
Y
S
Site 33
Y373
A
Y
D
Q
G
I
R
Y
S
F
T
F
E
L
R
Site 34
S374
Y
D
Q
G
I
R
Y
S
F
T
F
E
L
R
D
Site 35
T376
Q
G
I
R
Y
S
F
T
F
E
L
R
D
T
G
Site 36
T382
F
T
F
E
L
R
D
T
G
R
Y
G
F
L
L
Site 37
Y385
E
L
R
D
T
G
R
Y
G
F
L
L
P
E
S
Site 38
S392
Y
G
F
L
L
P
E
S
Q
I
R
A
T
C
E
Site 39
T397
P
E
S
Q
I
R
A
T
C
E
E
T
F
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation