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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPA1
Full Name:
Carboxypeptidase A1
Alias:
Type:
Mass (Da):
47140
Number AA:
419
UniProt ID:
P15085
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S61
R
G
P
A
H
P
G
S
P
I
D
V
R
V
P
Site 2
S85
F
L
E
S
H
G
I
S
Y
E
T
M
I
E
D
Site 3
S95
T
M
I
E
D
V
Q
S
L
L
D
E
E
Q
E
Site 4
S109
E
Q
M
F
A
F
R
S
R
A
R
S
T
D
T
Site 5
S113
A
F
R
S
R
A
R
S
T
D
T
F
N
Y
A
Site 6
T114
F
R
S
R
A
R
S
T
D
T
F
N
Y
A
T
Site 7
T116
S
R
A
R
S
T
D
T
F
N
Y
A
T
Y
H
Site 8
Y122
D
T
F
N
Y
A
T
Y
H
T
L
E
E
I
Y
Site 9
T151
S
K
I
Q
I
G
N
T
Y
E
G
R
P
I
Y
Site 10
Y152
K
I
Q
I
G
N
T
Y
E
G
R
P
I
Y
V
Site 11
Y158
T
Y
E
G
R
P
I
Y
V
L
K
F
S
T
G
Site 12
S167
L
K
F
S
T
G
G
S
K
R
P
A
I
W
I
Site 13
Y200
A
K
K
I
T
Q
D
Y
G
Q
D
A
A
F
T
Site 14
T239
T
N
R
M
W
R
K
T
R
S
H
T
A
G
S
Site 15
S241
R
M
W
R
K
T
R
S
H
T
A
G
S
L
C
Site 16
T243
W
R
K
T
R
S
H
T
A
G
S
L
C
I
G
Site 17
S246
T
R
S
H
T
A
G
S
L
C
I
G
V
D
P
Site 18
S264
W
D
A
G
F
G
L
S
G
A
S
S
N
P
C
Site 19
S267
G
F
G
L
S
G
A
S
S
N
P
C
S
E
T
Site 20
S268
F
G
L
S
G
A
S
S
N
P
C
S
E
T
Y
Site 21
S272
G
A
S
S
N
P
C
S
E
T
Y
H
G
K
F
Site 22
T274
S
S
N
P
C
S
E
T
Y
H
G
K
F
A
N
Site 23
Y275
S
N
P
C
S
E
T
Y
H
G
K
F
A
N
S
Site 24
S288
N
S
E
V
E
V
K
S
I
V
D
F
V
K
D
Site 25
Y314
S
Y
S
Q
L
L
M
Y
P
Y
G
Y
K
T
E
Site 26
Y316
S
Q
L
L
M
Y
P
Y
G
Y
K
T
E
P
V
Site 27
T320
M
Y
P
Y
G
Y
K
T
E
P
V
P
D
Q
D
Site 28
S333
Q
D
E
L
D
Q
L
S
K
A
A
V
T
A
L
Site 29
T338
Q
L
S
K
A
A
V
T
A
L
A
S
L
Y
G
Site 30
Y344
V
T
A
L
A
S
L
Y
G
T
K
F
N
Y
G
Site 31
S363
A
I
Y
Q
A
S
G
S
T
I
D
W
T
Y
S
Site 32
T368
S
G
S
T
I
D
W
T
Y
S
Q
G
I
K
Y
Site 33
Y369
G
S
T
I
D
W
T
Y
S
Q
G
I
K
Y
S
Site 34
Y375
T
Y
S
Q
G
I
K
Y
S
F
T
F
E
L
R
Site 35
S376
Y
S
Q
G
I
K
Y
S
F
T
F
E
L
R
D
Site 36
T378
Q
G
I
K
Y
S
F
T
F
E
L
R
D
T
G
Site 37
T384
F
T
F
E
L
R
D
T
G
R
Y
G
F
L
L
Site 38
Y387
E
L
R
D
T
G
R
Y
G
F
L
L
P
A
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation