PhosphoNET

           
Protein Info 
   
Short Name:  HOXB2
Full Name:  Homeobox protein Hox-B2
Alias:  Homeobox B2; HOX2; Hox-2.8; HOX2H; HXB2; K8
Type:  Transcription factor
Mass (Da):  37914
Number AA:  356
UniProt ID:  P14652
International Prot ID:  IPI00027261
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0008015  GO:0006355  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S14REIGFINSQPSLAEC
Site 2T34AVLETFQTSSIKEST
Site 3S36LETFQTSSIKESTLI
Site 4S40QTSSIKESTLIPPPP
Site 5T41TSSIKESTLIPPPPP
Site 6T52PPPPFEQTFPSLQPG
Site 7S55PFEQTFPSLQPGAST
Site 8S61PSLQPGASTLQRPRS
Site 9T62SLQPGASTLQRPRSQ
Site 10S68STLQRPRSQKRAEDG
Site 11S103PWMKEKKSAKKPSQS
Site 12S108KKSAKKPSQSATSPS
Site 13S110SAKKPSQSATSPSPA
Site 14T112KKPSQSATSPSPAAS
Site 15S113KPSQSATSPSPAASA
Site 16S115SQSATSPSPAASAVP
Site 17T148GGARRLRTAYTNTQL
Site 18Y150ARRLRTAYTNTQLLE
Site 19T151RRLRTAYTNTQLLEL
Site 20T153LRTAYTNTQLLELEK
Site 21Y167KEFHFNKYLCRPRRV
Site 22T202RMKHKRQTQHREPPD
Site 23S231PAEEPAASPGGPSAS
Site 24S236AASPGGPSASRAAWE
Site 25S238SPGGPSASRAAWEAC
Site 26S296PLPEDVFSGRQDSPF
Site 27S301VFSGRQDSPFLPDLN
Site 28S325LSGGLSPSLQGSLDS
Site 29S329LSPSLQGSLDSPVPF
Site 30S332SLQGSLDSPVPFSEE
Site 31S337LDSPVPFSEEELDFF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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