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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOXB2
Full Name:
Homeobox protein Hox-B2
Alias:
Homeobox B2; HOX2; Hox-2.8; HOX2H; HXB2; K8
Type:
Transcription factor
Mass (Da):
37914
Number AA:
356
UniProt ID:
P14652
International Prot ID:
IPI00027261
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0008015
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
R
E
I
G
F
I
N
S
Q
P
S
L
A
E
C
Site 2
T34
A
V
L
E
T
F
Q
T
S
S
I
K
E
S
T
Site 3
S36
L
E
T
F
Q
T
S
S
I
K
E
S
T
L
I
Site 4
S40
Q
T
S
S
I
K
E
S
T
L
I
P
P
P
P
Site 5
T41
T
S
S
I
K
E
S
T
L
I
P
P
P
P
P
Site 6
T52
P
P
P
P
F
E
Q
T
F
P
S
L
Q
P
G
Site 7
S55
P
F
E
Q
T
F
P
S
L
Q
P
G
A
S
T
Site 8
S61
P
S
L
Q
P
G
A
S
T
L
Q
R
P
R
S
Site 9
T62
S
L
Q
P
G
A
S
T
L
Q
R
P
R
S
Q
Site 10
S68
S
T
L
Q
R
P
R
S
Q
K
R
A
E
D
G
Site 11
S103
P
W
M
K
E
K
K
S
A
K
K
P
S
Q
S
Site 12
S108
K
K
S
A
K
K
P
S
Q
S
A
T
S
P
S
Site 13
S110
S
A
K
K
P
S
Q
S
A
T
S
P
S
P
A
Site 14
T112
K
K
P
S
Q
S
A
T
S
P
S
P
A
A
S
Site 15
S113
K
P
S
Q
S
A
T
S
P
S
P
A
A
S
A
Site 16
S115
S
Q
S
A
T
S
P
S
P
A
A
S
A
V
P
Site 17
T148
G
G
A
R
R
L
R
T
A
Y
T
N
T
Q
L
Site 18
Y150
A
R
R
L
R
T
A
Y
T
N
T
Q
L
L
E
Site 19
T151
R
R
L
R
T
A
Y
T
N
T
Q
L
L
E
L
Site 20
T153
L
R
T
A
Y
T
N
T
Q
L
L
E
L
E
K
Site 21
Y167
K
E
F
H
F
N
K
Y
L
C
R
P
R
R
V
Site 22
T202
R
M
K
H
K
R
Q
T
Q
H
R
E
P
P
D
Site 23
S231
P
A
E
E
P
A
A
S
P
G
G
P
S
A
S
Site 24
S236
A
A
S
P
G
G
P
S
A
S
R
A
A
W
E
Site 25
S238
S
P
G
G
P
S
A
S
R
A
A
W
E
A
C
Site 26
S296
P
L
P
E
D
V
F
S
G
R
Q
D
S
P
F
Site 27
S301
V
F
S
G
R
Q
D
S
P
F
L
P
D
L
N
Site 28
S325
L
S
G
G
L
S
P
S
L
Q
G
S
L
D
S
Site 29
S329
L
S
P
S
L
Q
G
S
L
D
S
P
V
P
F
Site 30
S332
S
L
Q
G
S
L
D
S
P
V
P
F
S
E
E
Site 31
S337
L
D
S
P
V
P
F
S
E
E
E
L
D
F
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation