PhosphoNET

           
Protein Info 
   
Short Name:  HSD3B1
Full Name:  3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
Alias:  3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I;Trophoblast antigen FDO161G;3-beta-hydroxy-5-ene steroid dehydrogenase;Progesterone reductase;Delta-5-3-ketosteroid isomerase
Type: 
Mass (Da):  42252
Number AA:  373
UniProt ID:  P14060
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S48PELREEFSKLQNKTK
Site 2S133IEVAGPNSYKEIIQN
Site 3Y155ENTWPAPYPHSKKLA
Site 4T182KNGGTLYTCALRPMY
Site 5Y189TCALRPMYIYGEGSR
Site 6Y191ALRPMYIYGEGSRFL
Site 7S199GEGSRFLSASINEAL
Site 8S201GSRFLSASINEALNN
Site 9S213LNNNGILSSVGKFST
Site 10S214NNNGILSSVGKFSTV
Site 11S248QDPKKAPSIRGQFYY
Site 12Y255SIRGQFYYISDDTPH
Site 13S257RGQFYYISDDTPHQS
Site 14T260FYYISDDTPHQSYDN
Site 15T271SYDNLNYTLSKEFGL
Site 16S273DNLNYTLSKEFGLRL
Site 17S282EFGLRLDSRWSFPLS
Site 18S285LRLDSRWSFPLSLMY
Site 19Y309SFLLRPIYTYRPPFN
Site 20T310FLLRPIYTYRPPFNR
Site 21Y311LLRPIYTYRPPFNRH
Site 22Y340KAQRDLAYKPLYSWE
Site 23Y344DLAYKPLYSWEEAKQ
Site 24S345LAYKPLYSWEEAKQK
Site 25T353WEEAKQKTVEWVGSL
Site 26S359KTVEWVGSLVDRHKE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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